Short-term hyperglycemia and hyperinsulinemia improve insulin action but do not alter glucose action in normal humans

Effects of Growth Hormone on Insulin Action in Man: Mechanisms of Insulin Resistance, Impaired Suppression of Glucose Production, and Impaired Stimulation of Glucose Utilization

1982 • 434 citations

Effect of chronic hyperglycemia on in vivo insulin secretion in partially pancreatectomized rats.

1987 • 335 citations

Chronic hyperglycemia is associated with impaired glucose influence on insulin secretion. A study in normal rats using chronic in vivo glucose infusions.

1986 • 287 citations

Increased β-Cell Secretory Capacity as Mechanism for Islet Adaptation to Nicotinic Acid-Induced Insulin Resistance

1989 • 181 citations

Minimal chronic hyperglycemia is a critical determinant of impaired insulin secretion after an incomplete pancreatectomy.

1988 • 172 citations

Severe Diabetes Induced in Subtotally Depancreatized Dogs by Sustained Hyperglycemia

1988 • 113 citations

Treatment with a Somatostatin Analog Decreases Pancreatic B-Cell and Whole Body Sensitivity to Glucose*

1990 • 95 citations

6 Insulin sensitivity in the intact organism

1987 • 45 citations

Differential Effects of Prolonged Hyperglycemia onin Vivoandin VitroInsulin Secretion in Rats

1991 • 34 citations