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Current and Emerging Treatment Strategies for Cutaneous T-cell Lymphoma

Data up to Jan 2025

Published2010
Citations98
References85

Total Citations Per Year

Abstract

References (85)

WHO-EORTC classification for cutaneous lymphomas

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Treatment of Cutaneous T-Cell Lymphoma by Extracorporeal Photochemotherapy

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Phase 2 trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) for refractory cutaneous T-cell lymphoma (CTCL)

2006 • 1,094 citations

Phase IIB Multicenter Trial of Vorinostat in Patients With Persistent, Progressive, or Treatment Refractory Cutaneous T-Cell Lymphoma

2007 • 990 citations

Revisions to the staging and classification of mycosis fungoides and Sézary syndrome: a proposal of the International Society for Cutaneous Lymphomas (ISCL) and the cutaneous lymphoma task force of the European Organization of Research and Treatment of Cancer (EORTC)

2008 • 965 citations

Gastrosplenic Fistula From Hodgkin's Lymphoma

2009 • 735 citations

Bexarotene Is Effective and Safe for Treatment of Refractory Advanced-Stage Cutaneous T-Cell Lymphoma: Multinational Phase II-III Trial Results

2001 • 685 citations

Pivotal Phase III Trial of Two Dose Levels of Denileukin Diftitox for the Treatment of Cutaneous T-Cell Lymphoma

2001 • 612 citations

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Kidney Cancer

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Inhibitor of histone deacetylation, depsipeptide (FR901228), in the treatment of peripheral and cutaneous T-cell lymphoma: a case report

2001 • 451 citations

Histone Deacetylase Inhibitors

2004 • 412 citations

EORTC consensus recommendations for the treatment of mycosis fungoides/Sézary syndrome

2006 • 404 citations

Phase 2 study of alemtuzumab (anti-CD52 monoclonal antibody) in patients with advanced mycosis fungoides/Sézary syndrome

2003 • 390 citations

Phase II Trial of Proteasome Inhibitor Bortezomib in Patients With Relapsed or Refractory Cutaneous T-Cell Lymphoma

2007 • 277 citations

Recombinant Leukocyte A Interferon: An Active Agent in Advanced Cutaneous T-Cell Lymphomas

1984 • 273 citations

Histopathologic Staging at Initial Diagnosis of Mycosis Fungoides and the Sézary Syndrome

1988 • 270 citations

Long-term efficacy, curative potential, and carcinogenicity of topical mechlorethamine chemotherapy in cutaneous T cell lymphoma

1989 • 261 citations

Topical Corticosteroids for Mycosis Fungoides

1998 • 234 citations

Interferon alfa-2a in the treatment of cutaneous T cell lymphoma

1989 • 226 citations

Gemcitabine Treatment in Pretreated Cutaneous T-Cell Lymphoma: Experience in 44 Patients

2000 • 225 citations

Multicenter study of pegylated liposomal doxorubicin in patients with cutaneous T‐cell lymphoma

2003 • 215 citations

Clinical efficacy of zanolimumab (HuMax-CD4): two phase 2 studies in refractory cutaneous T-cell lymphoma

2007 • 207 citations

Phase 1 and 2 Trial of Bexarotene Gel for Skin-Directed Treatment of Patients With Cutaneous T-Cell Lymphoma

2002 • 203 citations

Cutaneous T Cell Lymphoma

2001 • 184 citations

Photochemotherapy for cutaneous T cell lymphoma

1984 • 182 citations

Narrowband UVB phototherapy for early-stage mycosis fungoides

2002 • 176 citations

U.K. consensus statement on the use of extracorporeal photopheresis for treatment of cutaneous T-cell lymphoma and chronic graft-versus-host disease

2008 • 169 citations

Gemcitabine as frontline treatment for cutaneous T‐cell lymphoma

2005 • 155 citations

Ultraviolet-B Phototherapy for Early-Stage Cutaneous T-cell Lymphoma

1992 • 151 citations

Phase II Evaluation of Gemcitabine Monotherapy for Cutaneous T-Cell Lymphoma

2006 • 149 citations

Narrowband (311-nm) UV-B Therapy for Small Plaque Parapsoriasis and Early-Stage Mycosis Fungoides

1999 • 149 citations

Treatment of patients with advanced mycosis fungoides and Sézary syndrome with alemtuzumab

2003 • 143 citations

Narrowband TL-01 Phototherapy for Patch-Stage Mycosis Fungoides

2000 • 136 citations

The growth of cutaneous T-cell lymphoma is stimulated by immature dendritic cells

2002 • 132 citations

Mycosis fungoides: management with topical nitrogen mustard.

1987 • 127 citations

Experience with total skin electron beam therapy in combination with extracorporeal photopheresis in the management of patients with erythrodermic (T4) mycosis fungoides

2000 • 125 citations

Interferon in the treatment of cutaneous T-cell lymphoma

2003 • 119 citations

A phase-1 trial of bexarotene and denileukin diftitox in patients with relapsed or refractory cutaneous T-cell lymphoma

2005 • 110 citations

Adenovirus-mediated intralesional interferon-γ gene transfer induces tumor regressions in cutaneous lymphomas

2004 • 107 citations

Pentostatin Therapy of T-Cell Lymphomas With Cutaneous Manifestations

1999 • 103 citations

Total skin electron beam therapy followed by adjuvant psoralen/ultraviolet-A light in the management of patients with T1 and T2 cutaneous T-cell lymphoma (mycosis fungoides)

1997 • 102 citations

2-Chlorodeoxyadenosine: an active agent in the treatment of cutaneous T- cell lymphoma

1992 • 102 citations

Combined modality therapy for cutaneous T-cell lymphoma

1996 • 99 citations

Extracorporeal photopheresis for the treatment of cutaneous T-cell lymphoma

1992 • 96 citations

Chemotherapy with etoposide, vincristine, doxorubicin, bolus cyclophosphamide, and oral prednisone in patients with refractory cutaneous T-cell lymphoma

1999 • 96 citations

Activity of Fludarabine Monophosphate in Patients With Advanced Mycosis Fungoides: A Southwest Oncology Group Study

1990 • 95 citations

Phase II study of pentostatin and intermittent high-dose recombinant interferon alfa-2a in advanced mycosis fungoides/Sézary syndrome.

1992 • 95 citations

Systemic chemotherapy and extracorporeal photochemotherapy for T3 and T4 cutaneous T-cell lymphoma patients who have achieved a complete response to total skin electron beam therapy

1995 • 90 citations

Phase II trial of 2-chlorodeoxyadenosine for the treatment of cutaneous T-cell lymphoma [see comments]

1996 • 87 citations

Total skin electron radiation for patients with erythrodermic cutaneous T-cell lymphoma (mycosis fungoides and the S�zary syndrome)

1999 • 84 citations

2-Chlorodeoxyadenosine: an active agent in the treatment of cutaneous T- cell lymphoma

1992 • 82 citations

T‐cell depletion and autologous stem cell transplantation in the management of tumour stage mycosis fungoides with peripheral blood involvement

2001 • 80 citations

Additional courses of total skin electron beam therapy in the treatment of patients with recurrent cutaneous T-cell lymphoma

1996 • 71 citations

PUVA Treatment of Erythrodermic and Plaque-Type Mycosis Fungoides

1987 • 67 citations

A phase II open-label study of recombinant human interleukin-12 in patients with stage IA, IB, or IIA mycosis fungoides

2006 • 67 citations

Graft-versus-lymphoma effect in refractory cutaneous T-cell lymphoma after reduced-intensity HLA-matched sibling allogeneic stem cell transplantation

2004 • 66 citations

2-Chlorodeoxyadenosine therapy in patients with T-cell lymphoproliferative disorders

1994 • 65 citations

The North American Experience with Photopheresis

1999 • 55 citations

Prognosis, clinical outcomes and quality of life issues in cutaneous T-cell lymphoma

2003 • 54 citations

Combined treatment with oral etretinate and electron beam therapy in patients with cutaneous T-cell lymphoma (mycosis fungoides and Sézary syndrome)

1992 • 51 citations

Extracorporeal photopheresis for the treatment of Sézary syndrome using a novel treatment protocol

2008 • 46 citations

Total skin electron beam therapy in the management of mycosis fungoides.

1991 • 41 citations

Review of extracorporeal photopheresis in early‐stage (IA, IB, and IIA) cutaneous T‐cell lymphoma

2007 • 38 citations

Interferon resistance of cutaneous T-cell lymphoma–derived clonal T-helper 2 cells allows selective viral replication

2001 • 32 citations

Phototherapy and photopharmacology.

1985 • 31 citations

Phase II Trial of Oral Panobinostat (LBH589) in Patients with Refractory Cutaneous T-Cell Lymphoma (CTCL).

2008 • 28 citations

Retinoids in Cutaneous T Cell Lymphomas

1987 • 25 citations

Total skin electron beam and total nodal irradiation of cutaneous T-cell lymphoma

1991 • 24 citations

Topical mechlorethamine. Cutaneous changes in patients with mycosis fungoides after its administration

1977 • 24 citations

Photopheresis ? Extracorporeal irradiation of 8-MOP containing blood ? A new therapeutic modality

1987 • 22 citations

PROPEL: A Multi-Center Phase 2 Open-Label Study of Pralatrexate (PDX) with Vitamin B12 and Folic Acid Supplementation in Patients with Replapsed or Refractory Peripheral T-Cell Lymphoma

2008 • 20 citations

Optimal combination with PUVA: rationale and clinical trial update.

2007 • 20 citations

Efficacy and safety of denileukin diftitox (Dd) in a phase III, double-blind, placebo-controlled study of CD25+ patients with cutaneous T-cell lymphoma (CTCL)

2007 • 19 citations

Long-term treatment of CTCL with the oral PNP inhibitor, forodesine

2009 • 19 citations

Final Clinical Results of a Phase 2 NCI Multicenter Study of Romidepsin in Recurrent Cutaneous T-Cell Lymphoma (Molecular Analyses Included).

2008 • 18 citations

Topical Mechlorethamine

1977 • 17 citations

Efficacy and safety of denileukin diftitox (Dd) in cutaneous T-cell lymphoma (CTCL) patients: Integrated analysis of three large phase III trials

2008 • 14 citations

Pralatrexate (PDX) IS Active in Cutaneous T-Cell Lymphoma: Preliminary Results of a Multi-Center Dose-Finding Trial.

2008 • 13 citations

Drug evaluation: TG-1042, an adenovirus-mediated IFNgamma gene delivery for the intratumoral therapy of primary cutaneous lymphomas.

2007 • 9 citations

[Significance of PUVA therapy for adult T-cell leukemia/lymphoma--PUVA therapy can induce apoptosis in leukemic cells].

1995 • 4 citations

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Current and Emerging Treatment Strategies for Cutaneous T-cell Lymphoma (2010) – Drugs | Metascience Observatory Explorer