Can antioxidant supplementation slow the aging process?

Cellular defenses against damage from reactive oxygen species

1994 • 2,393 citations

Vitamin E Consumption and the Risk of Coronary Heart Disease in Men

1993 • 2,363 citations

Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS)

1996 • 2,163 citations

Antioxidant and redox regulation of gene transcription

1996 • 1,999 citations

Vitamin E supplementation enhances cell-mediated immunity in healthy elderly subjects

1990 • 581 citations

Antioxidant supplementation decreases oxidative DNA damage in human lymphocytes.

1996 • 560 citations

Interaction among vitamin C, vitamin E, and beta-carotene

1995 • 460 citations

Aging and oxidative stress: Modulation by dietary restriction

1996 • 450 citations

The integrated antioxidant system

1995 • 434 citations

Effect of dietary antioxidant combinations in humans. Protection of LDL by vitamin E but not by beta-carotene.

1993 • 408 citations

The Antioxidant Vitamins and Cardiovascular Disease: A Critical Review of Epidemiologic and Clinical Trial Data

1995 • 407 citations

The Effect of α-Tocopherol Supplementation on LDL Oxidation

1995 • 378 citations

Antioxidants and immune response in aged persons: overview of present evidence

1995 • 296 citations

Epidemiologic evidence for beta-carotene and cancer prevention

1995 • 290 citations

d-alpha-tocopherol inhibition of vascular smooth muscle cell proliferation occurs at physiological concentrations, correlates with protein kinase C inhibition, and is independent of its antioxidant properties.

1995 • 290 citations

Protective effect of vitamin E on exercise-induced oxidative damage in young and older adults

1993 • 249 citations

Effects of d-alpha-tocopherol supplementation on experimentally induced primate atherosclerosis.

1992 • 240 citations

Antioxidants and Aging

2012 • 235 citations

Supplementation With Low Doses of Vitamin E Protects LDL From Lipid Peroxidation in Men and Women

1995 • 223 citations

Natural antioxidants in human health and disease

1995 • 218 citations

Effect of combined supplementation with alpha-tocopherol, ascorbate, and beta carotene on low-density lipoprotein oxidation.

1993 • 199 citations

Effects of d-α-Tocopherol Supplementation on Experimentally Induced Primate Atherosclerosis

1992 • 188 citations

Vitamin E prevents exercise-induced DNA damage

1995 • 180 citations

Effect of selenium and vitamin E on the development of experimental atherosclerosis in rabbits

1991 • 178 citations

The Dual Roles of Nutrients as Antioxidants and Prooxidants: Their Effects on Tumor Cell Growth

1996 • 155 citations

Vitamin E: a sensor and an information transducer of the cell oxidation state

1995 • 142 citations

The antioxidant supplement myth

1994 • 125 citations

Effect of dietary 2-mercaptoethanol on the life span, immune system, tumor incidence and lipid peroxidation damage in spleen lymphocytes of aging BC3F1 mice

1984 • 101 citations

Pharmacological doses of vitamin E and insulin action in elderly subjects

1994 • 94 citations

The effect of modest vitamin E supplementation on lipid peroxidation products and other cardiovascular risk factors in diabetic patients

1996 • 70 citations

Hormonal modulation of antioxidant enzyme activities in young and old rats

1995 • 68 citations

Supplementation with Selenium Restores Age-Related Decline in Immune Cell Function

1995 • 52 citations

Effect of dietary vitamin E on lipofuscin accumulation with age in the rat brain

1994 • 36 citations

Effects of cellular aging on the induction of c-fos by antioxidant treatments

1996 • 29 citations

Dietary antioxidants, cancer, and atherosclerotic heart disease.

1994 • 28 citations

Effects of Aging and Antioxidants on Glucose Transport in Rat Adipocytes

1995 • 21 citations

Role of Antioxidants in the Maintenance of Immune Functions

1994 • 13 citations

Deleted Work

1955 • 0 citations