The contribution of polymorphism in the alcohol dehydrogenase β subunit to alcohol sensitivity in a Japanese population

Alcohol and aldehyde dehydrogenase genotypes and alcoholism in Chinese men.

1991 • 613 citations

Distribution of ADH2 and ALDH2 genotypes in different populations

1992 • 547 citations

Developmental changes and polymorphism in human alcohol dehydrogenase

1971 • 375 citations

Ethnic Differences in Alcohol Sensitivity

1972 • 373 citations

Racial differences in alcohol sensitivity: A new hypothesis

1979 • 259 citations

Liver alcohol dehydrogenase and aldehyde dehydrogenase in the Japanese: isozyme variation and its possible role in alcohol intoxication.

1980 • 236 citations

Genotyping of human alcohol dehydrogenases at the ADH2 and ADH3 loci following DNA sequence amplification

1988 • 233 citations

AN ATYPICAL HUMAN ALCOHOL DEHYDROGENASE

1965 • 191 citations

Liver alcohol dehydrogenase in Japanese: high population frequency of atypical form and its possible role in alcohol sensitivity.

1975 • 173 citations

Alcohol dehydrogenase isozymes in adult human stomach and liver: evidence for activity of the ADH₃ locus

1972 • 166 citations

Polymorphism of alcohol and aldehyde dehydrogenase genes and alcoholic cirrhosis in Chinese patients.

1994 • 165 citations

Characterization of the three genotypes of low Km aldehyde dehydrogenase in a Japanese population

1994 • 164 citations

Vasomotor sensitivity to alcohol in diverse Mongoloid populations.

1973 • 157 citations

Polymorphism of alcohol and aldehyde dehydrogenase genes and alcoholic cirrhosis in chinese patients

1994 • 145 citations

Human liver alcohol dehydrogenase: purification and kinetic characterization of the .beta.2.beta.2, .beta.2.beta.1, .alpha..beta.2, and .beta.2.gamma.1 "Oriental" isoenzymes

1984 • 143 citations

Molecular analysis of the human class I alcohol dehydrogenase gene family and nucleotide sequence of the gene encoding the beta subunit.

1986 • 139 citations

Genotypes of alcohol-metabolizing enzymes in Japanese with alcohol liver diseases: a strong association of the usual Caucasian-type aldehyde dehydrogenase gene (ALDH1(2)) with the disease.

1988 • 124 citations

ATYPICAL HUMAN LIVER ALCOHOL DEHYDROGENASE

1968 • 116 citations

Human liver alcohol dehydrogenase: amino acid substitution in the beta 2 beta 2 Oriental isozyme explains functional properties, establishes an active site structure, and parallels mutational exchanges in the yeast enzyme.

1984 • 99 citations

Three human alcohol dehydrogenase subunits: cDNA structure and molecular and evolutionary divergence.

1986 • 83 citations

Genetic polymorphism of alcohol and aldehyde dehydrogenase and the effects on alcohol metabolism.

1993 • 79 citations

Alcohol Metabolism, Alcohol Intolerance, and Alcoholism

1990 • 74 citations

ATYPICAL HUMAN LIVER ALCOHOL DEHYDROGENASE

1968 • 73 citations

Alcohol metabolizing enzymes: Studies of isozymes in human biopsies and cultured fibroblasts

1979 • 72 citations

Enzymatic and structural differences between usual and atypical human liver alcohol dehydrogenases.

1981 • 70 citations

Biology of disease. Alcoholism and aldehydism: new biomedical concepts.

1984 • 66 citations

Molecular cloning of a full-length cDNA for human alcohol dehydrogenase.

1985 • 59 citations

Extrahepatic, Differential Expression of Four Classes of Human Alcohol Dehydrogenase

1993 • 48 citations

Cutaneous Vascular Sensitivity to Lower Aliphatic Alcohols and Aldehydes in Orientals

1985 • 45 citations

Pharmacogenetics of alcohol dehydrogenase (ADH)

1990 • 41 citations

Liver alcohol dehydrogenase in a Japanese population.

1972 • 38 citations

Direct determination of usual (Caucasian-type) and atypical (Oriental-type) alleles of the class I human alcohol dehydrogenase-2 locus

1988 • 25 citations

[Association between alcoholics and the genotypes of ALDH2, ADH2, ADH3 as well as P-4502E1].

1995 • 14 citations

Gene frequencies of alcohol dehydrogenase2 (ADH2) and aldehyde dehydrogenase2 (ALDH2) in five Chinese minorities

1994 • 9 citations