Differential changes of adrenoceptor‐ and muscarinic receptor‐linked prostacyclin synthesis by the aorta and urinary bladder of the diabetic rat

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

1987 • 10,774 citations

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Inositol trisphosphate and diacylglycerol as second messengers

1984 • 3,535 citations

How is the level of free arachidonic acid controlled in mammalian cells?

1982 • 1,193 citations

A23187: A Divalent Cation Ionophore

1972 • 1,182 citations

Comparative pharmacology of endothelium‐derived relaxing factor, nitric oxide and prostacyclin in platelets

1987 • 824 citations

Sustained diacylglycerol formation from inositol phospholipids in angiotensin II-stimulated vascular smooth muscle cells.

1986 • 491 citations

Activation of protein kinase C by elevation of glucose concentration: proposal for a mechanism in the development of diabetic vascular complications.

1989 • 374 citations

Functional consequences of streptozotocin-induced diabetes mellitus, with particular reference to the cardiovascular system.

1992 • 323 citations

Role of Ca2+-ATPases in regulation of cellular Ca2+ signalling, as studied with the selective microsomal Ca2+-ATPase inhibitor, thapsigargin

1990 • 276 citations

TPA-induced contraction of isolated rabbit vascular smooth muscle

1984 • 266 citations

Phorbol ester-induced contraction of arterial smooth muscle and inhibition of α-adrenergic response

1984 • 216 citations

Decreased vascular prostacyclin in experimental diabetes

1978 • 203 citations

Thrombin-stimulated elevation of human endothelial-cell cytoplasmic free calcium concentration causes prostacyclin production

1988 • 190 citations

Arachidonic acid deficiency in streptozotocin-induced diabetes.

1983 • 189 citations

Prostacyclin modulates cholesteryl ester hydrolytic activity by its effect on cyclic adenosine monophosphate in rabbit aortic smooth muscle cells.

1982 • 170 citations

Fatty Acids and Their Prostaglandin Derivatives: Inhibitors of Proliferation in Aortic Smooth Muscle Cells

1977 • 157 citations

Eicosanoid Synthesis by Human Urinary Bladder Mucosa: Pathological Implications

1987 • 94 citations

Urinary Bladder Prostanoids—Their Synthesis, Function and possible Role in the Pathogenesis and Treatment of Disease

1987 • 80 citations

9 Diabetes Mellitus, Vascular Disease and Thrombosis

1986 • 78 citations

Eicosanoid effects on cell proliferation in vitro: Relevance to atherosclerosis

1984 • 74 citations

New Methods of Endocrine Management of Prostatic Cancer

1987 • 71 citations

The Smooth Muscle of Rat Bladder in the Early Stages of Streptozotocin‐induced Diabetes

1984 • 68 citations

Experimental diabetes mellitus inhibits prostacyclin synthesis by the rat penis: pathological implications

1985 • 68 citations

A phorbol ester inhibits the release of endothelium-derived relaxing factor

1987 • 63 citations

Adrenergic modulation of vascular prostacyclin (PGI2) secretion

1985 • 63 citations

Vasoconstrictor-evoked prostaglandin synthesis in cultured vascular smooth muscle

1983 • 48 citations

Production of 6-Oxo-Prostaglandin F1α by Rat Aorta: Influence of Diabetes, Insulin Treatment, and Caloric Deprivation

1981 • 46 citations

Altered fatty acid composition in the plasma, platelets, and aorta of the streptozotocin-induced diabetic rat

1988 • 46 citations

Release of endothelium‐derived relaxing factor from pig cultured aortic endothelial cells, as assessed by changes in endothelial cell cyclic GMP content, is inhibited by a phorbol ester

1990 • 45 citations

Unidirectional flux rate of cholesterol and fatty acids into the intestine of rats with drug-induced diabetes mellitus: effect of variations in the effective resistance of the unstirred water layer and the bile acid micelle.

1980 • 39 citations

N‐myc suppression and cell cycle arrest at G₁ phase by prostaglandins

1990 • 35 citations

Increased release of prostaglandins from the mesenteric vascular bed of diabetic animals: The effects of glucose and insulin

1986 • 32 citations

Excitatory receptor-prostanoid synthesis coupling in smooth muscle: mediation by calcium, protein kinase C and G proteins.

1988 • 32 citations

Prostanoid synthesis by the rat urinary bladder: evidence for stimulation through muscarine receptor-linked calcium channels

1986 • 32 citations

Effect of endothelium removal on stimulatory and inhibitory modulation of rat aortic prostacyclin synthesis

1989 • 29 citations

The role of the diacylglycerol-protein kinase C system in mediating adrenoceptor-prostacyclin synthesis coupling in the rat aorta

1987 • 29 citations

Gastrin and growth of the alimentary tract in the streptozotocin-diabetic rat

1982 • 22 citations

The Effect of Streptozotocin-Induced Diabetes on PGI ₂ Synthesis by the Rat Bladder

1986 • 17 citations

Prostacyclin in the circulation of patients with vascular disorders undergoing surgery

1986 • 16 citations

Vascular and Platelet Eicosanoids, Smoking and Atherosclerosis

1990 • 16 citations

Fasting and diabetes mellitus elicit opposite effects on agonist-stimulated prostacyclin synthesis by the rat aorta

1987 • 13 citations

Effect of Insulin and Dietary Myoinositol on Muscarinic Receptor Alterations in Diabetic Rat Bladder

1992 • 13 citations

Release of prostacyclin from the human aorta

1988 • 13 citations

Changes in eicosanoid synthesis in the cerebrum, cerebellum and brain stem of the diabetic rat.

1987 • 8 citations

The protein kinase C family for the regulation of cellular functions

1992 • 7 citations

Amplification fo prostaglandin I2 production by thapsigargin

1991 • 2 citations