Maintenance chemotherapy for childhood acute lymphoblastic leukemia: relation of bone-marrow and hepatotoxicity to the concentration of methotrexate in erythrocytes

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2014 • 12,091 citations

Dose: A critical factor in cancer chemotherapy

1980 • 851 citations

Variable Bioavailability of Oral Mercaptopurine

1983 • 268 citations

Drug dosage and remission duration in childhood lymphocytic leukemia

1971 • 238 citations

Childhood leukaemia: a relationship between intracellular 6‐mercaptopurine metabolites and neutropenia

2004 • 161 citations

Childhood leukaemia: a relationship between intracellular 6‐ mercaptopurine metabolites and neutropenia.

1983 • 155 citations

METHOTREXATE SYSTEMIC CLEARANCE INFLUENCES PROBABILITY OF RELAPSE IN CHILDREN WITH STANDARD-RISK ACUTE LYMPHOCYTIC LEUKAEMIA

1984 • 117 citations

A Population‐Based Study of Childhood Acute Lymphoblastic Leukemia Diagnosed from July 1981 through June 1985 in the Five Nordic Countries

1987 • 100 citations

Large Interindividual Variations in the Pharmacokinetics of Oral 6‐Mercaptopurine in Maintenance Therapy of Children with Acute Leukaemia and Non‐Hodgkin Lymphoma

1986 • 55 citations

Methotrexate absorption in children with acute lymphoblastic leukemia.

1981 • 48 citations

Unpredictable serum levels after oral methotrexate in children with acute lymphoblastic leukaemia

1979 • 45 citations

Methotrexate and its polyglutamate derivatives in erythrocytes during and after weekly low-dose oral methotrexate therapy of children with acute lymphoblastic leukemia

1988 • 43 citations

Pharmacokinetics of erythrocyte methotrexate in children with acute lymphoblastic leukemia during maintenance treatment

1986 • 35 citations

Pharmacokinetics of low-dose methotrexate in children receiving maintenance therapy for acute lymphoblastic leukaemia

1982 • 32 citations

White Cell Count During Maintenance Chemotherapy for Standard-Risk Childhood Acute Lymphoblastic Leukemia: Relation to Relapse Rate

1988 • 25 citations

Folic Acid Supplements in Vitamin Tablets: A Determinant of Hematological Drug Tolerance in Maintenance Therapy of Childhood Acute Lymphoblastic Leukemia

1986 • 24 citations

Enzymatic Assay for Methotrexate in Erythrocytes

1985 • 21 citations

Methotrexate pharmacokinetics in age-fractionated erythrocytes

1986 • 20 citations

Pharmacokinetics of erythrocyte methotrexate after high-dose methotrexate

1982 • 18 citations

Sickle Lepore hemoglobin identified in a black American infant.

1983 • 5 citations