Stimulation and Expansion of a Human T-Cell Subpopulation by a Monoclonal Antibody to T-Cell Receptor Molecule

High resolution two-dimensional electrophoresis of proteins.

1975 • 19,515 citations

Continuous cultures of fused cells secreting antibody of predefined specificity

1975 • 17,037 citations

A human T cell-specific cDNA clone encodes a protein having extensive homology to immunoglobulin chains

1984 • 1,262 citations

Isolation of cDNA clones encoding T cell-specific membrane-associated proteins

1984 • 1,239 citations

The major histocompatibility complex-restricted antigen receptor on T cells. I. Isolation with a monoclonal antibody.

1983 • 861 citations

Clonotypic structures involved in antigen-specific human T cell function. Relationship to the T3 molecular complex.

1983 • 833 citations

Sequence relationships between putative T-cell receptor polypeptides and immunoglobulins

1984 • 719 citations

OKT3: A monoclonal anti-human T lymphocyte antibody with potent mitogenic properties

1980 • 718 citations

Both a monoclonal antibody and antisera specific for determinants unique to individual cloned helper T cell lines can substitute for antigen and antigen-presenting cells in the activation of T cells.

1983 • 654 citations

Complete primary structure of a heterodimeric T-cell receptor deduced from cDNA sequences

1984 • 652 citations

A third rearranged and expressed gene in a clone of cytotoxic T lymphocytes

1984 • 528 citations

Tumor-specific antigen of murine T-lymphoma defined with monoclonal antibody.

1982 • 526 citations

A third type of murine T-cell receptor gene

1984 • 491 citations

Somatic recombination in a murine T-cell receptor gene

1984 • 468 citations

Enzymic iodination. A probe for accessible surface proteins of normal and neoplastic lymphocytes

1971 • 464 citations

Mouse T cell antigen receptor: Structure and organization of constant and joining gene segments encoding the β polypeptide

1984 • 407 citations

Sequence and expression of transcripts of the human T-cell receptor β- chain genes

1984 • 380 citations

Genomic organization and sequence of T-cell receptor β-chain constant- and joining-region genes

1984 • 377 citations

Does OKT3 monoclonal antibody react with an antigen-recognition structure on human T cells?

1981 • 306 citations

The human t cell antigen receptor is encoded by variable, diversity, and joining gene segments that rearrange to generate a complete V gene

1984 • 306 citations

Amino acid sequence of homogeneous antibodies to dextran and DNA rearrangments in heavy chain V-region gene segments

1980 • 272 citations

Primary structure of human T-cell receptor α-chain

1984 • 245 citations

The mouse T cell receptor: Structural heterogeneity of molecules of normal T cells defined by Xenoantiserum

1983 • 217 citations

Complexity of human T-cell antigen receptor β-chain constant- and variable-region genes

1984 • 213 citations

The major histocompatibility complex-restricted antigen receptor on T cells in mouse and man: Identification of constant and variable peptides

1983 • 209 citations

Complexity of the human T lymphocyte-specific cell surface antigen T3.

1982 • 170 citations

Comparison of T3-associated 49- and 43-kilodalton cell surface molecules on individual human T-cell clones: evidence for peptide variability in T-cell receptor structures.

1983 • 133 citations

Idiotype-like molecules on cells of a human T cell leukemia.

1983 • 126 citations

Antibody directed at a surface structure inhibits cytolytic but not suppressor function of human T lymphocytes

1981 • 115 citations

Inhibition of specific cell-mediated cytotoxicity by monoclonal antibodies to human T cell antigens

1981 • 105 citations

Peptide variability exists within alpha and beta subunits of the T cell receptor for antigen.

1983 • 101 citations

Purification and NH2-terminal amino acid sequencing of the beta subunit of a human T-cell antigen receptor.

1984 • 99 citations

Complete amino acid sequence of variable domains from two monoclonal human anti-gamma globulins of the Wa cross-idiotypic group: suggestion that the J segments are involved in the structural correlate of the idiotype.

1981 • 86 citations

Noncovalently bonded subunits of 22 and 28 kd are rapidly internalized by T cells reacted with anti-Leu-4 antibody.

1983 • 86 citations

Immunoglobulin-like nature of the α-chain of a human T-cell antigen/MHC receptor

1984 • 83 citations

Identical Vβ T-cell receptor genes used in alloreactive cytotoxic and antigen plus I–A specific helper T cells

1985 • 79 citations

Molecular analysis of T cell receptor (Ti) variable region (V) gene expression. Evidence that a single Ti beta V gene family can be used in formation of V domains on phenotypically and functionally diverse T cell populations.

1985 • 59 citations

Partial Primary Structure of the Alpha and Beta Chains of Human Tumor T-Cell Receptors

1985 • 57 citations

Modulation induction of the T3 antigen by OKT3 antibody is monocyte dependent.

1984 • 45 citations

Stimulation of a subset of normal resting T lymphocytes by a monoclonal antibody to a crossreactive determinant of the human T cell antigen receptor.

1985 • 38 citations

Genetic markers of the antigen-specific T cell receptor locus.

1985 • 35 citations

A human T cell tumor which expresses the putative T cell antigen receptor

1984 • 29 citations

T cell antiidiotypic antibodies reveal differences between two human leukemias.

1984 • 29 citations

Identification of shared antigenic determinants of the putative human T lymphocyte antigen receptor.

1984 • 27 citations

Biochemical characterization of the human t6 antigen: A comparison between T6 and murine TL

1984 • 12 citations

Human B-cell-stimulatory-factor production by both T4+ and T8+ lymphocytes

1984 • 3 citations