Solvent effects on the stability of A7U7p

Electric Moments of Molecules in Liquids

1936 • 5,172 citations

Some Factors in the Interpretation of Protein Denaturation

1959 • 4,817 citations

Optimal computer folding of large RNA sequences using thermodynamics and auxiliary information

1981 • 3,596 citations

The molecular theory of polyelectrolyte solutions with applications to the electrostatic properties of polynucleotides

1978 • 2,873 citations

Improved Estimation of Secondary Structure in Ribonucleic Acids

1973 • 2,302 citations

Thermodynamic analysis of ion effects on the binding and conformational equilibria of proteins and nucleic acids: the roles of ion association or release, screening, and ion effects on water activity

1978 • 1,651 citations

Kinetics of renaturation of DNA

1968 • 1,446 citations

Mechanism of protein stabilization by glycerol: preferential hydration in glycerol-water mixtures

1981 • 1,170 citations

The stabilization of proteins by sucrose.

1981 • 1,084 citations

DNA fragments differing by single base-pair substitutions are separated in denaturing gradient gels: correspondence with melting theory.

1983 • 895 citations

Signal recognition particle contains a 7S RNA essential for protein translocation across the endoplasmic reticulum

1982 • 766 citations

Stability of ribonucleic acid double-stranded helices

1974 • 760 citations

Increased thermal stability of proteins in the presence of sugars and polyols

1979 • 746 citations

Rates of formation and thermal stabilities of RNA:DNA and DNA:DNA duplexes at high concentrations of formamide

1977 • 713 citations

Estimation of Secondary Structure in Ribonucleic Acids

1971 • 692 citations

Free energy of imperfect nucleic acid helices

1973 • 507 citations

Base-stacking and base-pairing contributions to helix stability: thermodynamics of double-helix formation with CCGG, CCGGp, CCGGAp, ACCGGp, CCGGUp, and ACCGGUp

1983 • 489 citations

Thermodynamic and kinetic examination of protein stabilization by glycerol

1981 • 473 citations

Thermodynamics of protein denaturation. III. Denaturation of ribonuclease in water and in aqueous urea and aqueous ethanol mixtures

1967 • 422 citations

Globin mRNA Sequences: Analysis of Base Pairing and Evolutionary Implications

1978 • 403 citations

Statistical mechanical deconvolution of thermal transitions in macromolecules. I. Theory and application to homogeneous systems

1978 • 349 citations

Ribonuclease P: an enzyme with an essential RNA component.

1978 • 299 citations

Disassembly and reconstitution of signal recognition particle

1983 • 242 citations

Calorimetric study of thermally induced conformational transitions of ribonuclease A and certain of its derivatives

1970 • 242 citations

Polyelectrolyte Theories and their Applications to DNA

1982 • 234 citations

Heats of the helix–coil transitions of the poly A–poly U complexes

1968 • 230 citations

Sequence-Determined DNA Separations

1984 • 210 citations

Thermodynamics of the denaturation of lysozyme in alcohol-water mixtures

1979 • 204 citations

Thermodynamics and kinetics of the helix‐coil transition of oligomers containing GC base pairs

1973 • 187 citations

The Relationship of Structure to the Effectiveness of Denaturing Agents for Deoxyribonucleic Acid

1963 • 182 citations

Snurps and scyrps

1981 • 181 citations

Interactions of proteins with solvent components in 8 m urea

1981 • 162 citations

Self-complementary oligoribonucleotides: Adenylic acid-uridylic acid block copolymers

1971 • 160 citations

Hydrophobic hydration around a pair of apolar species in water

1979 • 159 citations

Simplification of the empirical relationship between melting temperature of DNA, its GC content and concentration of sodium ions in solution

1971 • 158 citations

Thermodynamics of (dG-dC)3 double-helix formation in water and deuterium oxide

1981 • 146 citations

Dielectric constants of amide-water systems

1973 • 139 citations

Calorimetric and spectroscopic investigation of the helix-to-coil transition of a ribo-oligonucleotide: rA7U7

1975 • 137 citations

Expression of the mitochondrial genome in Hela cells

1971 • 127 citations

HYDROPHOBIC STACKING OF BASES AND THE SOLVENT DENATURATION OF DNA*

1964 • 126 citations

Effects of solute–solvent attractive forces on hydrophobic correlations

1980 • 125 citations

Method for predicting RNA secondary structure.

1975 • 122 citations

E. coli RNAase P has a required RNA component in vivo

1980 • 121 citations

Freezing points of aqueous alcohols. Free energy of interaction of the CHOH, CH2, CONH and CC functional groups in dilute aqueous solutions

1978 • 121 citations

Helix formation by d(TA) oligomers

1970 • 108 citations

The Heat of the Reaction between Polyriboadenylic Acid and Polyribouridylic Acid

1963 • 105 citations

The Effect of Aqueous Alcohol Solutions on the Thermal Transition of Ribonuclease^1a,b

1965 • 104 citations

Laser temperature-jump study of stacking in adenylic acid polymers

1979 • 100 citations

Vapor pressure studies of hydrophobic interactions. formation of benzene-benzene and cyclohexane-cyclohexanol dimers in dilute aqueous solution

1981 • 99 citations

Interaction of alcohols with proteins

1978 • 99 citations

A semiempirical extension of polyelectrolyte theory to the treatment of oligoelectrolytes: Application to oligonucleotide helix‐coil transitions

1978 • 96 citations

Equimolar addition of oligoribonucleotides with T4 RNA ligase

1977 • 89 citations

Solvent effects on the dynamics of (dG‐dC)₃

1983 • 89 citations

Solution studies of the nucleic acid bases and related model compounds. Solubility in aqueous alcohol and glycol solutions

1972 • 84 citations

Polarization and Dielectric Constant of Liquids

1936 • 83 citations

Hydrophobic solvation of nonspherical solutes

1980 • 81 citations

Solvent effects on the kinetics and thermodynamics of stacking in poly(cytidylic acid)

1981 • 75 citations

Thermodynamics of base interaction in (A)n and (A·U)n

1978 • 71 citations

Solvent effects on dinucleotide conformation

1972 • 68 citations

Calculation of the rate of uncoiling of the DNA molecule

1960 • 66 citations

Thermodynamic investigation of the helix-coil transitions of a polyribonucleotide system

1969 • 65 citations

Heat of the reaction forming the three‐stranded poly (A + 2U) complex

1965 • 63 citations

Sequential folding of a messenger RNA molecule

1981 • 55 citations

Thermodynamic Studies of RNA Stability

1984 • 53 citations

Computer-aided prediction of RNA secondary structures

1982 • 53 citations

The solvophobic theory for the prediction of molecular conformations and biopolymer bindings in solutions with recent direct experimental tests

1980 • 51 citations

Calorimetric determination of the heat capacity changes associated with the conformational transitions of polyriboadenylic acid and polyribouridylic acid

1977 • 50 citations

Solvent effects on the thermodynamics of double-helix formation in (dG-dC)3

1981 • 49 citations

Solution studies of the nucleic acid bases and related model compounds. Solubility in aqueous urea and amide solutions

1974 • 45 citations

Calculation of the dielectric constant of polyatomic fluids with the interaction site formalism

1982 • 43 citations

Hydrophobic interactions and osmotic second virial coefficients for methanol in water

1980 • 41 citations

Calorimetric measurements of the transition enthalpy of DNA in aqueous urea solutions

1977 • 41 citations

THE EFFECTS OF COMBINING TWO DIFFERENT ALCOHOLS ON THE HEAT‐INDUCED REVERSIBLE DENATURATION OF RIBONUCLEASE

1974 • 40 citations

Effect of sodium ion on the high‐resolution melting of lambda DNA

1979 • 39 citations

Theory of oligonucleotide stabilization. I. The effect of single-strand stacking

1973 • 36 citations

Laser temperature jump study of solvent effects on poly(adenylic acid) stacking

1980 • 33 citations

Statistical mechanical deconvolution of thermal transitions in macromolecules. III. Application to double‐stranded to single‐stranded transitions of nucleic acids

1978 • 32 citations

Theory of nonprimitive electrolyte solutions: generalized electrostatic model for the equilibrium properties of ionic–polar mixtures

1979 • 30 citations

Small changes in free energy assignments for unpaid bases do not affect predicted secondary structures in single stranded RNA

1982 • 28 citations

Purine–water interactions in base stacking

1980 • 26 citations

The role of solvent in the stabilization of helical structure: The low pH RIBO A8 and A10 double helices in mixed solvents

1978 • 16 citations

THE EFFECTS FROM COMBINING UREA AND AN ALCOHOL ON THE HEAT‐INDUCED REVERSIBLE DENATURATION OF RIBONUCLEASE

1976 • 14 citations

Some Physical Properties of Dimethyl Sulfoxide-Water Binary System

1962 • 11 citations

Molecular pair effects and the breakdown of Onsager’s dielectric theory

1980 • 7 citations