Binding of boronic acids to chymotrypsin

Catalysis in chemistry and enzymology

1969 • 3,236 citations

Mechanism of Action of Proteolytic Enzymes

1965 • 473 citations

The Spectrophotometric Determination of the Operational Normality of an α-Chymotrypsin Solution

1961 • 407 citations

Subtilisin. Stereochemical mechanism involving transition-state stabilization

1972 • 376 citations

The Reversible Hydration of Carbonyl Compounds

1966 • 285 citations

Carbon nuclear magnetic resonance studies of the histidine residue in α-lytic protease. Implications for the catalytic mechanism of serine proteases

1973 • 239 citations

Aldehydes as Inhibitors of Papain

1972 • 169 citations

2-Phenylethaneboronic acid, a possible transition-state analog for chymotrypsin

1971 • 144 citations

Organoboron Compounds, and the Study of Reaction Mechanisms. Primary Aliphatic Boronic Acids¹

1938 • 143 citations

Spectrophotometric Investigations of the Mechanism of α-Chymotrypsin-catalyzed Hydrolyses. Detection of the Acyl-enzyme Intermediate^1-3

1962 • 104 citations

7 Chymotrypsin-Chemical Properties and Catalysis

1971 • 100 citations

6 The Structure of Chymotrypsin

1971 • 84 citations

THE STRUCTURE OF CHYMOSTATIN, A CHYMOTRYPSIN INHIBITOR

1973 • 65 citations

The preparation of organolithium compounds by the transmetalation reaction part VIII. β-styryllithium

1964 • 57 citations

The Dissociation Constants of the Chlorophenyl and Phenetyl Boric Acids¹

1934 • 50 citations

The Free Energies of Hydrlysis of Some Esters and Thiol Esters of Acetic Acid

1964 • 46 citations

The Formation of an Acyl-enzyme Intermediate in the α-Chymotrypsin-catalyzed Hydrolyses of Non-labile trans-Cinnamic Acid Esters^1-3

1962 • 37 citations

The Stereochemistry of Mercuri-deboronation of 1-Phenylethaneboronic Acid¹

1965 • 37 citations

Spectroscopic changes accompanying some reactions of trypsin and α-chymotrypsin

1966 • 35 citations

Peptide aldehydes inhibiting chymotrypsin

1972 • 34 citations

Investigations of the Chymotrypsin-catalyzed Hydrolysis of Specific Substrates

1967 • 34 citations

Formation of Grignard Reagents from cis- and trans-β-Bromostyrenes

1964 • 33 citations

Preferential binding of competitive inhibitors to the monomeric form of α-chymotrypsin

1972 • 32 citations

Transfer reactions involving boron—XVIII

1969 • 24 citations

15 Subtilisin: X-Ray Structure

1971 • 23 citations

Binding‐catalysis relationship in α‐chymotrypsin action as revealed from reversible inhibition study of phenylalkylboronic acids

1972 • 20 citations

Interpretation of the ultraviolet spectrum of trans-cinnamoyl-α-chymotrypsin

1963 • 10 citations

Search for the addition of monodentate nucleophiles to boric and benzeneboronic acids in water

1972 • 7 citations