(±)- Trans -2-(3-methoxy-5-methylsulfonyl-4-propoxyphenyl)-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran (L-659,989), a novel, potent PAF receptor antagonist

Platelet-activating factor. Evidence for 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine as the active component (a new class of lipid chemical mediators).

1979 • 1,203 citations

Antihypertensive activity of an alkyl ether analog of phosphatidylcholine

1979 • 562 citations

Platelet-activating factor induces a platelet-dependent bronchoconstriction unrelated to the formation of prostaglandin derivatives

1980 • 422 citations

CV-3988 - A specific antagonist of platelet activating factor (PAF)

1983 • 341 citations

Pharmacological actions of WEB 2086, a new specific antagonist of platelet activating factor.

1987 • 263 citations

Pathobiology of the intravenous infusion of acetyl glyceryl ether phosphorylcholine (AGEPC), a synthetic platelet-activating factor (PAF), in the rabbit.

1980 • 259 citations

Potent ulcerogenic actions of platelet-activating factor on the stomach

1986 • 250 citations

Specific binding of phospholipid platelet-activating factor by human platelets.

1982 • 233 citations

Specific receptor sites for 1-0-alkyl-2-0-acetyl-sn-glycero-3-phosphocholine (platelet activating factor) on rabbit platelet and guinea pig smooth muscle membranes

1983 • 230 citations

BN 52021 and related compounds: A new series of highly specific PAF-acether receptor antagonists isolated from Ginkgo biloba L.

1985 • 207 citations

Specific binding by human polymorphonuclear leucocytes of the immunological mediator 1-O-hexadecyl/octadecyl-2-acetyl-sn-glycero-3-phosphorylcholine.

1983 • 140 citations

Vascular actions of synthetic PAF-acether (a synthetic platelet-activating factor) in the rat: Evidence for a platelet independent mechanism

1982 • 138 citations

trans-2,5-Bis-(3,4,5-trimethoxyphenyl)tetrahydrofuran. An orally active specific and competitive receptor antagonist of platelet activating factor.

1985 • 120 citations

Specific binding sites for platelet activating factor in human lung tissues

1985 • 117 citations

PAF-acether specific binding sites: 2. Design of specific antagonists

1986 • 115 citations

Platelet-activating factor today

1983 • 102 citations

Platelet-Activating Factor in Late Asthmatic Response

1987 • 60 citations

Conformation and activity of tetrahydrofuran lignans and analogs as specific platelet-activating-factor antagonists

1986 • 56 citations

PAF-acether specific binding sites: 1. quantitative SAR study of PAF-acether isosteres

1986 • 47 citations

Platelet activating factor intravenous infusion in rats stimulates vascular lysosomal hydrolase secretion independent of blood neutrophils

1984 • 43 citations

Chapter 20. Platelet-Activating Factor: Multifaceted Biochemical and Physiological Mediator

1985 • 41 citations

Structure-activity relationships of kadsurenone analogues

1987 • 35 citations

Schild regressions as indicators of non-equilibrium steady-states and heterogeneous receptor populations

1985 • 31 citations

Platelet activating factor and asthma

1986 • 24 citations

Inhibition of the platelet activating factor (PAF)-induced in vivo responses in rats by trans-2,5-(3,4,5-trimethoxyphenyl) tetrahydrofuran (L-652,731), a PAF receptor antagonist.

1986 • 24 citations

Pharmacology of the Late Response to Allergen and Its Relevance to Asthma Prophylaxis

1985 • 22 citations

Structure of ginkgolide B (BN 52021) monohydrate, a highly specific PAF/acether receptor antagonist isolated from Ginko biboba L.

1986 • 18 citations

Evidence favouring PAF rather than leukotrienes in the pathogenesis of asthma

1986 • 17 citations

Deleted Work

1955 • 0 citations