Defence against allergic sensitization in the healthy lung: the role of inhalation tolerance

Mite faeces are a major source of house dust allergens

1981 • 547 citations

Dendritic cells with antigen-presenting capability reside in airway epithelium, lung parenchyma, and visceral pleura.

1986 • 370 citations

Characterization of nonlymphoid cells derived from rat peripheral lymph

1983 • 343 citations

Development of allergy in children

1979 • 308 citations

Regulation of IgE Synthesis

1984 • 301 citations

MHC class II antigen-bearing dendritic cells in pulmonary tissues of the rat. Regulation of antigen presentation activity by endogenous macrophage populations.

1988 • 285 citations

Inhibition of specific IgE responses in mice by pre-exposure to inhaled antigen.

1981 • 229 citations

ATOPIC DISEASE IN SEVEN‐YEAR‐OLD CHILDREN Incidence in Relation to Family History

1977 • 221 citations

Immune Responses to Fed Protein Antigens in Mice. 3. Systemic Tolerance or Priming Is Related to Age at Which Antigen Is First Encountered

1984 • 221 citations

Acute experimental autoimmune encephalomyelitis in mice

1982 • 207 citations

Neonatal birch‐pollen contact and subsequent allergy to birch pollen

1980 • 203 citations

Down-regulation of immune responses in the lower respiratory tract: the role of alveolar macrophages.

1986 • 187 citations

Localization of T cells, macrophages and dendritic cells in rat respiratory tract tissue: implications for immune function studies.

1987 • 173 citations

ORAL TOLERANCE

1980 • 167 citations

Predisposing factors and the development of reaginic allergy in infancy

1976 • 162 citations

Clinical symptoms and IgE responses to common food proteins and inhalants in the first 7 years of life

1987 • 144 citations

Immunological responses to fed protein antigens in mice. I. Reversal of oral tolerance to ovalbumin by cyclophosphamide.

1982 • 136 citations

Expression of immune mechanisms in the lung.

1976 • 123 citations

Recent studies on the regulation of IgE antibody synthesis in experimental animals and man.

1980 • 120 citations

T cell activation by antigen-presenting cells from lung tissue digests: suppression by endogenous macrophages.

1985 • 110 citations

Induction of IgE-secreting cells and IgE isotype-specific suppressor T cells in the respiratory lymph nodes of rats in response to antigen inhalation

1985 • 109 citations

Suppression of IgE responses by antigen inhalation: studies on the role of genetic and environmental factors.

1987 • 86 citations

Inhibitory Activity of Unstimulated Alveolar Macrophages on T-Lymphocyte Blastogenic Response¹

1978 • 83 citations

Suppression of IgE responses in inbred rats by repeated respiratory tract exposure to antigen: Responder phenotype influences isotype specificity of induced tolerance

1984 • 79 citations

Immunoglobulin E antibodies to pollens augmented in dogs by virus vaccines.

1983 • 73 citations

Month of birth and grass pollen or mite sensitization in children with respiratory allergy: a significant relationship

1988 • 71 citations

Induction of IgE-isotype specific tolerance by passive antigenic stimulation of the respiratory mucosa.

1983 • 69 citations

Total and specific IgE (RAST) in atopic twins

1981 • 67 citations

House dust mite sensitivity in childhood asthma.

1978 • 66 citations

Functional characteristics of the veiled cells in afferent lymph from the rat intestine.

1986 • 65 citations

Down-regulation of immune responses to inhaled antigen: studies on the mechanism of induced suppression.

1985 • 58 citations

Interactions of viruses with the immune system.

1986 • 48 citations

Tolerance Induction via Antigen Inhalation: Isotype Specificity, Stability, and Involvement of Suppressor T Cells

1982 • 47 citations

RELATIONSHIP BETWEEN THE TIME OF BIRTH AND THE DEVELOPMENT OF IMMEDIATE HYPERSENSITIVITY TO GRASS‐POLLEN ANTIGENS

1979 • 42 citations

Effect of Influenza Virus Infection on Allergic Sensitization to Inhaled Antigen in Mice

1988 • 41 citations

IgE antibody suppression following aerosol exposure to antigens.

1981 • 40 citations

Crystallization of pertussigen from Bordetella pertussis

1981 • 38 citations

Immunogenicity and Tolerogenicity of a Major House Dust Mite Allergen, <i>Der p</i> l from <i>Dermatophagoides pteronyssinus</i>, in Mice and Rats

1987 • 36 citations

The effect of nitrogen dioxide on tracheal uptake and transport of horseradish peroxidase in the guinea pig.

1980 • 35 citations

Formation of IgE-binding factors by rat T lymphocytes. II. Mechanisms of selective formation of IgE-potentiating factors by treatment with Bordetella pertussis vaccine.

1981 • 33 citations

Suppression of IgE responses by antigen inhalation: failure of tolerance mechanism(s) in newborn rats.

1988 • 32 citations

Suppression of IgE responses by passive antigen inhalation: Dissociation of local (mucosal) and systemic immunity

1987 • 28 citations

Atopic Allergy and Serum IgE Concentrations in Randomly Selected Children Followed Up from 8 to 12 Years of Age

1984 • 24 citations

Delay in the Development of the Allergic Response to Metals Following Intratracheal Instillation

1978 • 18 citations

Induction of memory and effector suppressor T cells by perinatal exposure to antigen

1984 • 17 citations

Early allergen contacts

1986 • 13 citations