Definition of the single integration site of the pathogenicity locus in Clostridium difficile

Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold.

1982 • 5,284 citations

Antibiotic-Associated Pseudomembranous Colitis Due to Toxin-Producing Clostridia

1978 • 1,392 citations

A major superfamily of transmembrane facilitators that catalyse uniport, symport and antiport

1993 • 939 citations

The detection and classification of membrane-spanning proteins

1985 • 854 citations

Toxigenic clostridia

1990 • 626 citations

ABC transporters: bacterial exporters

1993 • 607 citations

Clostridium difficile: its disease and toxins

1988 • 574 citations

Nucleotide sequence of an Escherichia coli chromosomal hemolysin

1985 • 572 citations

Bacterial Pathogenesis : A Molecular Approach

1994 • 570 citations

Bacterial pathogenesis: A molecular approach

1995 • 456 citations

Secretion of cyclolysin, the calmodulin-sensitive adenylate cyclase-haemolysin bifunctional protein of Bordetella pertussis.

1988 • 436 citations

Molecular genetics and pathogenesis of Clostridium perfringens

1991 • 403 citations

Multidrug resistance pumps in bacteria: variations on a theme

1994 • 314 citations

Deletions of chromosomal regions coding for fimbriae and hemolysins occur in vitro and in vivo in various extra intestinal Escherichia coli isolates

1990 • 302 citations

Genetic basis of virulence in Shigella species

1991 • 293 citations

Molecular characterization of the Clostridium difficile toxin A gene

1990 • 279 citations

Transfer RNA genes frequently serve as integration sites for prokaryotic genetic elements

1989 • 276 citations

Computer-aided analyses of transport protein sequences: gleaning evidence concerning function, structure, biogenesis, and evolution

1994 • 263 citations

Cloning, nucleotide sequence, and characterization of genes encoding the secretion function of the Pasteurella haemolytica leukotoxin determinant

1989 • 239 citations

Tn552, a novel transposable element from Staphylococcus aureus

1990 • 232 citations

Conservation of secretion pathways for pathogenicity determinants of plant and animal bacteria

1993 • 226 citations

The E. coli gene encoding heat stable toxin is a bacterial transposon flanked by inverted repeats of IS1

1979 • 178 citations

Nucleotide sequence ofClostridium difficiletoxin B gene

1990 • 177 citations

Comparative sequence analysis of theClostridium difficile toxins A and B

1992 • 160 citations

Nucleotide sequence of the type A streptococcal exotoxin (erythrogenic toxin) gene from Streptococcus pyogenes bacteriophage T12

1986 • 157 citations

Rapid field inversion gel electrophoresis in combination with an rRNA gene probe in the epidemiological evaluation of staphylococci

1990 • 154 citations

Bacillus licheniformis bacitracin‐resistance ABC transporter: relationship to mammalian multidrug resistance

1995 • 111 citations

Clostridium difficile toxin A carries a C-terminal repetitive structure homologous to the carbohydrate binding region of streptococcal glycosyltransferases

1990 • 110 citations

Cloning and disruption of a putative NaH-antiporter gene of Enterococcus hirae.

1992 • 102 citations

Evidence of a novel staphylococcal mec-encoded element (mecR) controlling expression of penicillin-binding protein 2'

1990 • 90 citations

Nucleotide sequence of streptococcal pyrogenic exotoxin type C

1988 • 85 citations

Genetics and Molecular Biology of Anaerobic Bacteria

1993 • 82 citations

Clostridium difficile toxin B induces reorganization of actin, vinculin, and talin in cultured cells

1988 • 73 citations

Genetics and molecular biology of anaerobic bacteria

1993 • 68 citations

How to become a pathogen

1994 • 59 citations

Nucleotide sequence of the penicillinase repressor gene penI of Bacillus licheniformis and regulation of penP and penI by the repressor

1986 • 58 citations

Serotyping of Clostridium difficile

1988 • 52 citations

Nucleotide sequence of Clostridium difficile toxin A

1990 • 50 citations

Cloning of Clostridium difficile toxin B gene and demonstration of high N-terminal homology between toxin A and B

1990 • 48 citations

Isolation of a novel transposon which carries the Escherichia coli enterotoxin STII gene

1985 • 45 citations

Sequencing and analysis of the gene encoding the α-toxin of Clostridium novyi proves its homology to toxins A and B of Clostridium difficile

1995 • 40 citations

Cloning and Characterization of Overlapping DNA Fragments of the Toxin A Gene of Clostridium difficile

1989 • 33 citations

Bacterial protein toxins

1995 • 32 citations

Functional domains of the penicillinase repressor of Bacillus licheniformis

1993 • 23 citations

The Role of Bacteriophages and Plasmids in the Production of Toxins and Other Biologically Active Substances by Clostridium botulinum and Clostridium novyi

1993 • 10 citations

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