Insulin Binding to the Blood‐Brain Barrier in the Streptozotocin Diabetic Rat

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

BMDP Statistical Software 1981.

1984 • 5,347 citations

Insulin receptors are widely distributed in the central nervous system of the rat

1978 • 1,092 citations

Insulin-Dependent Regulation of Insulin Receptor Concentrations: A Direct Demonstration in Cell Culture

1974 • 1,037 citations

Diabetogenic action of streptozotocin: relationship of dose to metabolic response

1969 • 950 citations

Mathematical theory of complex ligand-binding systems at equilibrium: Some methods for parameter fitting

1972 • 615 citations

Monoiodoinsulin: Demonstration of its biological activity and binding to fat cells and liver membranes

1971 • 521 citations

Receptor-Mediated Transport of Insulin Across Endothelial Cells

1985 • 462 citations

Human Blood—Brain Barrier Insulin Receptor

1985 • 386 citations

Concentrations of Insulin and of Insulin Receptors in the Brain are Independent of Peripheral Insulin Levels

1979 • 324 citations

Differential responsiveness to insulin of endothelial and support cells from micro- and macrovessels.

1983 • 234 citations

Relationship between plasma and cerebrospinal fluid insulin levels of dogs.

1977 • 216 citations

Regional Concentrations of Insulin in the Rat Brain*

1983 • 216 citations

Insulin and insulin receptors in rodent brain

1981 • 197 citations

Neuropeptides and the Blood-Brain Barrier

1983 • 192 citations

Metabolic fuel and amino acid transport into the brain in experimental diabetes mellitus.

1982 • 185 citations

Insulin binds to brain blood vessels in vivo

1979 • 177 citations

A Direct In Vitro Demonstration of Insulin Binding to Isolated Brain Microvessels

1981 • 161 citations

Insulin is ubiquitous in extrapancreatic tissues of rats and humans.

1980 • 140 citations

Cerebral microvessels and derived cells in tissue culture: Isolation and preliminary characterization

1979 • 133 citations

Increased insulin binding by hepatic plasma membranes from diabetic rats: normalization by insulin therapy.

1977 • 115 citations

Neuroendocrine Perspectives

1984 • 104 citations

Characterization and Regulation of Insulin Receptors in Rat Brain

1984 • 101 citations

Processing of Insulin by Bovine Endothelial Cells in Culture: Internalization Without Degradation

1984 • 90 citations

The Failure of Rat Hypothalamic Tissues to Take up Labeled Insulin in Vivo or to Respond to Insulin in Vitro

1977 • 83 citations

Enhanced Insulin Binding to Blood-Brain Barrier In Vivo and to Brain Microvessels In Vitro in Newborn Rabbits

1985 • 83 citations

Evidence against extrapancreatic insulin synthesis.

1981 • 65 citations

The Insulin Receptor: Properties and Regulation

1977 • 54 citations

Enhanced insulin binding to blood-brain barrier in vivo and to brain microvessels in vitro in newborn rabbits

1985 • 46 citations

Impairments in availability of insulin to liver in vivo and in binding of insulin to purified hepatic plasma membrane during aging

1973 • 46 citations

RAPID TRANSPORT OF BIOLOGICALLY INTACT INSULIN THROUGH CULTURED ENDOTHELIAL CELLS

1984 • 43 citations

Insulin in the Central Nervous System

1983 • 38 citations

Uptake of Glucose Analogues into Cultured Cerebral Microvessel Endothelium

1985 • 34 citations

Insulin Binding to Brain Microvessels

1983 • 31 citations

Advances in Metabolic disorders

1983 • 30 citations

Induction of γ-Glutamyl Transpeptidase in Isolated Cerebral Endothelial Cells

1980 • 30 citations

Advances in Metabolic Disorders, Vol. 1

1964 • 26 citations

Downregulation Occurs Normally in Cultured Epstein-Barr Virus-transformed Lymphocytes from Patients with Extreme Insulin Resistance: Discrepancy Between Downregulation In Vivo and In Vitro

1984 • 7 citations

Downregulation occurs normally in cultured Epstein-Barr virus-transformed lymphocytes from patients with extreme insulin resistance. Discrepancy between downregulation in vivo and in vitro

1984 • 6 citations