DNA-targeted 2-nitroimidazoles: in vitro and in vivo studies

The Histological Structure of Some Human Lung Cancers and the Possible Implications for Radiotherapy

1955 • 2,174 citations

Ethidium fluorescence assays. Part 1. Physicochemical studies

1979 • 348 citations

Oxygen diffusion and the distribution of cellular radiosensitivity in tumours

1972 • 267 citations

Partition Coefficient as a Guide to the Development of Radiosensitizers Which Are Less Toxic Than Misonidazole

1980 • 214 citations

The importance of the pre-irradiation breathing times of oxygen and carbogen (5% CO2: 95% O2) on the in vivo radiation response of a murine sarcoma

1977 • 128 citations

Clinical trials of radiosensitizers: What should we expect?

1984 • 124 citations

Heterocyclic Pseudobases

1980 • 56 citations

Modification of the Radiation Sensitivity of Human Tumour Cells by a Bis-benzimidazole Derivative

1984 • 50 citations

Structure-activity Relationships in the Development of Hypoxic Cell Radiosensitizers

1980 • 36 citations

Radiosensitization of Mammalian Cells in Vitro by Nitroacridines

1990 • 30 citations

NLA-1 : A 2-nitroimidazole radiosensitizer targeted to DNA by intercalation

1992 • 28 citations

NLP-1: A DNA intercalating hypoxic cell radiosensitizer and cytotoxin

1989 • 25 citations

The development of some nitroimidazoles as hypoxic cell sensitizers.

1980 • 22 citations

Targeting Radiosensitizers to DNA by Attachment of an Intercalating Group: Nitroimidazole-Linked Phenanthridines

1991 • 22 citations

Growth delay in a murine squamous cell tumor after local radiation and concurrent infusional 5-Fluorouracil treatment

1986 • 20 citations

Mechanistic studies of enhanced in vitro radiosensitization and hypoxic cell cytotoxicity by targeting radiosensitizers to DNA via intercalation

1992 • 9 citations