Combined Use of the Adenosine A2A Antagonist KW-6002 with l-DOPA or with Selective D1 or D2 Dopamine Agonists Increases Antiparkinsonian Activity but Not Dyskinesia in MPTP-Treated Monkeys
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References (37)
Nomenclature and classification of purinoceptors.
1994 • 1,569 citations
Biochemical pathophysiology of Parkinson's disease.
1987 • 844 citations
Characterization of the A2 adenosine receptor labeled by [3H]NECA in rat striatal membranes.
1986 • 821 citations
Striatal Restricted Adenosine A2 Receptor (RDC8) Is Expressed by Enkephalin but Not by Substance P Neurons: An In Situ Hybridization Histochemistry Study
1991 • 527 citations
Amantadine as treatment for dyskinesias and motor fluctuations in Parkinson's disease
1998 • 504 citations
Subclasses of adenosine receptors in the central nervous system: Interaction with caffeine and related methylxanthines
1983 • 437 citations
Adenosine A2A Antagonist: A novel antiparkinsonian agent that does not provoke dyskinesia in Parkinsonian monkeys
1998 • 359 citations
Direct autoradiographic localization of adenosine A2 receptors in the rat brain using the A2-selective agonist, [3H]CGS 21680
1989 • 344 citations
Entacapone improves motor fluctuations in levodopa‐ treated Parkinson's disease patients
1997 • 295 citations
Overview of morphological changes in Parkinson's disease.
1987 • 275 citations
Adenosine A2A receptor antagonists as new agents for the treatment of Parkinson's disease
1997 • 264 citations
Chronic <scp>L</scp>‐DOPA administration induces dyskinesias in the 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine‐treated common marmoset (Callithrix jacchus)
1995 • 215 citations
Adenosine A2 receptors: Selective localization in the human basal ganglia and alterations with disease
1991 • 198 citations
Distribution of adenosine A2 receptor mRNA in the human brain
1991 • 173 citations
Action of caffeine and theophyllamine on supersensitive dopamine receptors: considerable enhancement of receptor response to treatment with DOPA and dopamine receptor agonists.
1974 • 166 citations
Pathogenesis of dyskinesias in parkinson's disease
1989 • 151 citations
The Role of Adenosine A2a Receptors in Regulating Gabaergic Synaptic Transmission in Striatal Medium Spiny Neurons
1996 • 143 citations
KF17837: A novel selective adenosine A2A receptor antagonist with anticataleptic activity
1994 • 142 citations
(E)-1,3-Dialkyl-7-methyl-8-(3,4,5-trimethoxystyryl)xanthines: potent and selective adenosine A2 antagonists
1992 • 138 citations
The role of adenosine A2a receptors in regulating GABAergic synaptic transmission in striatal medium spiny neurons
1996 • 137 citations
Adenosine A2A receptor antagonists as new agents for the treatment of Parkinson's disease
1997 • 129 citations
Stimulation of adenosine A2 receptors induces catalepsy
1991 • 111 citations
Inhibition by KF17837 of adenosine A2A receptor‐mediated modulation of striatal GABA and ACh release
1994 • 107 citations
Adenosine A2A receptors modify motor function in MPTP-treated common marmosets
1998 • 104 citations
Adenosine A2A antagonists with potent anti-cataleptic activity
1997 • 101 citations
Adenosine A2a Receptor‐Mediated Modulation of Striatal Acetylcholine Release In Vivo
1996 • 92 citations
KF17837 ((E)-8-(3,4-dimethoxystyryl)-1,3-dipropyl-7-methylxanthine) a potent and selective adenosine A2 receptor antagonist
1994 • 83 citations
Motor activity following the administration of selective D-1 and D-2 dopaminergic drugs to normal common marmosets
1991 • 73 citations
COMT inhibition
1998 • 65 citations
Adenosine A2 receptor regulation of apomorphine-induced turning in rats with unilateral striatal dopamine denervation
1993 • 59 citations
Striatal A2 receptor regulates apomorphine-induced turning in rats with unilateral dopamine denervation
1991 • 59 citations
Differential anti-parkinsonian effects of benzazepine D1 dopamine agonists with varying efficacies in the MPTP-treated common marmoset
1995 • 53 citations
Behavioral effects of intrastriatal caffeine mediated by adenosinergic modulation of dopamine
1991 • 50 citations
Motor activity following the administration of selective D-1 and D-2 dopaminergic drugs to MPTP-treated common marmosets
1992 • 47 citations
The effect of tolcapone on levodopa pharmacokinetics is independent of levodopa/carbidopa formulation
1998 • 34 citations
Influence of COMT inhibition on levodopa pharmacology and therapy
1998 • 24 citations
Practical Therapy of Parkinson's Disease
1987 • 11 citations