Effects of albumin on lipid synthesis, apo B-100 secretion, and LDL catabolism in HepG2 cells

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

THE DISTRIBUTION AND CHEMICAL COMPOSITION OF ULTRACENTRIFUGALLY SEPARATED LIPOPROTEINS IN HUMAN SERUM

1955 • 8,846 citations

The metabolism of very low density lipoprotein proteins I. Preliminary in vitro and in vivo observations

1972 • 1,831 citations

[19] Receptor-mediated endocytosis of low-density lipoprotein in cultured cells

1983 • 1,639 citations

Association of coronary atherosclerosis with hyperapobetalipoproteinemia [increased protein but normal cholesterol levels in human plasma low density (beta) lipoproteins].

1980 • 639 citations

The metabolism of low density lipoprotein in familial type II hyperlipoproteinemia

1972 • 629 citations

ARE APOLIPOPROTEINS BETTER DISCRIMINATORS THAN LIPIDS FOR ATHEROSCLEROSIS?

1979 • 547 citations

Oleate stimulates secretion of apolipoprotein B-containing lipoproteins from Hep G2 cells by inhibiting early intracellular degradation of apolipoprotein B.

1991 • 421 citations

The apolipoprotein B gene is constitutively expressed in HepG2 cells: regulation of secretion by oleic acid, albumin, and insulin, and measurement of the mRNA half-life.

1989 • 414 citations

Regulation of hepatic secretion of apolipoprotein B-containing lipoproteins: information obtained from cultured liver cells.

1993 • 371 citations

Assembly and secretion of hepatic very-low-density lipoprotein

1990 • 292 citations

Regulation of apoB secretion from HepG2 cells: evidence for a critical role for cholesteryl ester synthesis in the response to a fatty acid challenge.

1990 • 273 citations

Metabolic basis of hyperapobetalipoproteinemia. Turnover of apolipoprotein B in low density lipoprotein and its precursors and subfractions compared with normal and familial hypercholesterolemia.

1986 • 258 citations

Insulin modulation of hepatic synthesis and secretion of apolipoprotein B by rat hepatocytes.

1990 • 251 citations

The Hyperlipidemia of the Nephrotic Syndrome

1985 • 218 citations

Familial Combined Hyperlipidemia Workshop

1989 • 215 citations

Experimental reconstruction of metabolic pattern of lipid nephrosis: key role of hepatic protein synthesis in hyperlipemia.

1960 • 210 citations

Substrate delivery as a determinant of hepatic apoB secretion.

1993 • 202 citations

Stable isotopes show a direct relation between VLDL apoB overproduction and serum triglyceride levels and indicate a metabolically and biochemically coherent basis for familial combined hyperlipidemia.

1993 • 178 citations

Oleate-mediated stimulation of apolipoprotein B secretion from rat hepatoma cells. A function of the ability of apolipoprotein B to direct lipoprotein assembly and escape presecretory degradation.

1992 • 144 citations

The effect of low density lipoproteins, cholesterol, and 25-hydroxycholesterol on apolipoprotein B gene expression in HepG2 cells.

1992 • 136 citations

Lipoprotein apolipoprotein synthesis by human hepatoma cells in culture

1981 • 130 citations

Familial hypoalphalipoproteinemia in premature coronary artery disease.

1993 • 120 citations

Regulation of apolipoprotein B production and secretion in response to the change of intracellular cholesteryl ester contents in rabbit hepatocytes

1993 • 104 citations

Two new monoclonal antibody-based enzyme-linked assays of apolipoprotein B.

1986 • 92 citations

Hyperapobetalipoproteinemia. Plasma lipoprotein responses to oral fat load.

1986 • 84 citations

The unstirred water layer as a site of control of apolipoprotein B secretion.

1990 • 83 citations

Very low density lipoprotein secretion by cultured rat hepatocytes. Inhibition by albumin and other macromolecules.

1980 • 71 citations

Lipoprotein lipase modulates net secretory output of apolipoprotein B in vitro. A possible pathophysiologic explanation for familial combined hyperlipidemia.

1991 • 71 citations

Viscosity of culture medium as a regulator of synthesis and secretion of very low density lipoproteins by cultured hepatocytes.

1982 • 70 citations

Oleate-mediated Stimulation of Apolipoprotein B Secretion from Rat Hepatoma Cells

1992 • 56 citations

Pathogenesis of carbohydrate-induced hypertriglyceridemia using HepG2 cells as a model system.

1992 • 55 citations

Hepatic Synthesis of Lipoproteins and Apolipoproteins

1992 • 52 citations

Albumin Metabolism in the Nephrotic Syndrome: The Effect of Dietary Protein Intake

1988 • 50 citations

Oncotic pressure regulates gene transcriptions of albumin and apolipoprotein B in cultured rat hepatoma cells

1992 • 43 citations

Lipolysis is a prerequisite for lipid accumulation in HepG2 cells induced by large hypertriglyceridemic very low density lipoproteins.

1992 • 41 citations

The molecular mechanism for the assembly and secretion of ApoB-100-containing lipoproteins

1991 • 33 citations

The role of amino acids in ApoB100 synthesis and catabolism in human HepG2 cells.

1993 • 29 citations

Lipoprotein secretion by the human hepatoma cell line Hep G2: differential rates of accumulation of apolipoprotein B and lipoprotein lipids in tissue culture media in response to albumin, glucose and oleate

1991 • 22 citations

Interaction of apolipoprotein B-containing lipoprotein secreted by Hep G2 cells with receptors for low-density lipoprotein

1991 • 3 citations