AP2 inhibits cancer cell growth and activates p21WAF1/CIP1 expression

WAF1, a potential mediator of p53 tumor suppression

1993 • 8,360 citations

Inhibitors of mammalian G1 cyclin-dependent kinases.

1995 • 3,258 citations

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

1992 • 3,092 citations

Transcription factor AP-2 mediates induction by two different signal-transduction pathways: Protein kinase C and cAMP

1987 • 1,391 citations

Correlation of Terminal Cell Cycle Arrest of Skeletal Muscle with Induction of p21 by MyoD

1995 • 1,154 citations

p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage.

1995 • 1,114 citations

Positive and negative regulation of transcription in vitro: Enhancer-binding protein AP-2 is inhibited by SV40 T antigen

1987 • 969 citations

Transcriptional activation of the Cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937.

1996 • 922 citations

Cell Growth Arrest and Induction of Cyclin-Dependent Kinase Inhibitor p21 ^WAF1/CIP1 Mediated by STAT1

1996 • 796 citations

Induction of WAF1/CIP1 by a p53-independent pathway.

1994 • 773 citations

Transcription factor AP-2 essential for cranial closure and craniofacial development

1996 • 611 citations

Neural tube, skeletal and body wall defects in mice lacking transcription factor AP-2

1996 • 595 citations

Topological control of p21WAF1/CIP1 expression in normal and neoplastic tissues.

1995 • 593 citations

Cloning and expression of AP-2, a cell-type-specific transcription factor that activates inducible enhancer elements.

1988 • 578 citations

Analysis of the DNA-binding and activation properties of the human transcription factor AP-2.

1991 • 519 citations

Induction of p21 (WAF-1/CIP1) during differentiation.

1994 • 493 citations

CCAAT/enhancer-binding protein alpha (C/EBP alpha) inhibits cell proliferation through the p21 (WAF-1/CIP-1/SDI-1) protein.

1996 • 393 citations

Allelotype of head and neck squamous cell carcinoma.

1994 • 349 citations

Tumorigenicity in Human Melanoma Cell Lines Controlled by Introduction of Human Chromosome 6

1990 • 333 citations

Regulation of transcription factor AP-2 by the morphogen retinoic acid and by second messengers.

1989 • 260 citations

Regulation of p21WAF1/CIP1 expression by p53-independent pathways.

1996 • 240 citations

The developmentally regulated transcription factor AP-2 is involved in c-erbB-2 overexpression in human mammary carcinoma.

1995 • 228 citations

An AP-2 element acts synergistically with the cyclic AMP- and phorbol ester-inducible enhancer of the human proenkephalin gene.

1989 • 170 citations

Frequent loss of heterozygosity on chromosome 6 in human ovarian carcinoma

1993 • 126 citations

An alternatively spliced mRNA from the AP-2 gene encodes a negative regulator of transcriptional activation by AP-2.

1993 • 124 citations

Activation of Raf-1 and mitogen-activated protein kinases during monocytic differentiation of human myeloid leukemia cells.

1994 • 106 citations

Transcription Factor AP-2 Regulates Human Insulin-like Growth Factor Binding Protein-5 Gene Expression

1995 • 101 citations

N-ras oncogene causes AP-2 transcriptional self-interference, which leads to transformation.

1994 • 93 citations

Repression of a matrix metalloprotease gene by E1A correlates with its ability to bind to cell type-specific transcription factor AP-2.

1996 • 71 citations

Localization of the gene for the DNA-binding protein AP-2 to human chromosome 6p22.3-pter

1991 • 44 citations

Mechanisms of human melanoma cell growth and tumor suppression by chromosome 6.

1996 • 33 citations

Okadaic acid increased annexin I and induced differentiation of human promyelocytic leukemia cells

1995 • 5 citations