Non‐involvement ofrasmutations in flat colorectal adenomas and carcinomas

A genetic model for colorectal tumorigenesis

1990 • 11,800 citations

Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia

1985 • 9,128 citations

Genetic Alterations during Colorectal-Tumor Development

1988 • 6,691 citations

Identification of FAP Locus Genes from Chromosome 5q21

1991 • 2,358 citations

The evolution of cancer of the colon and rectum

1975 • 2,120 citations

Chromosome 17 Deletions and p53 Gene Mutations in Colorectal Carcinomas

1989 • 2,081 citations

Mutations of Chromosome 5q21 Genes in FAP and Colorectal Cancer Patients

1991 • 1,890 citations

Prevalence of ras gene mutations in human colorectal cancers

1987 • 1,866 citations

Identification of a Chromosome 18q Gene that Is Altered in Colorectal Cancers

1990 • 1,747 citations

Detection of high incidence of K-ras oncogenes during human colon tumorigenesis

1987 • 1,074 citations

Purification of DNA from formaldehyde fixed and paraffin embedded human tissue

1985 • 821 citations

Identification of a Gene Located at Chromosome 5q21 that Is Mutated in Colorectal Cancers

1991 • 758 citations

Altered Growth of Human Colon Cancer Cell Lines Disrupted at Activated Ki- ras

1993 • 627 citations

Activation of Ki-ras2 gene in human colon and lung carcinomas by two different point mutations

1983 • 553 citations

Early colorectal carcinoma with special reference to its development de novo

1989 • 388 citations

A dot-blot screening procedure for mutated ras oncogenes using synthetic oligodeoxynucleotides

1986 • 351 citations

Gastrointestinal Pathology

1980 • 236 citations

The evolution of cancer of the colon and rectum

2010 • 234 citations

Adenoma-carcinoma sequence or “de novo” Carcinogenesis?. A study of adenomatous remnants in a population-based series of large bowel cancers

1992 • 179 citations

Flat early cancers of the large intestine

1989 • 169 citations

Small Primary Adenocarcinomas of the Colon and Rectum

1962 • 159 citations

C-Ki-ras mutations in chronic ulcerative colitis and sporadic colon carcinoma

1990 • 150 citations

Clinicopathologic features of the flat adenoma

1991 • 118 citations

Activation of c-Ki-ras in human gastrointestinal dysplasias determined by direct sequencing of polymerase chain reaction products.

1990 • 100 citations

Infrequent point mutations of ras oncogenes in gastric cancers

1990 • 68 citations

Chromoscopy of the colon using indigo carmine dye with electrolyte lavage solution

1992 • 60 citations

K-ras activation in gastric epithelial tumors in Japanese

1991 • 48 citations

A PATHOLOGICAL STUDY ON COLORECTAL CANCER

1987 • 39 citations