Effects of GTP on Ca2+ movements across endoplasmic reticulum membranes

Purification and reconstitution of the calcium release channel from skeletal muscle

1988 • 928 citations

The yeast GTP-binding YPT1 protein and a mammalian counterpart are associated with the secretion machinery

1988 • 699 citations

myo-Inositol 1,4,5-trisphosphate. A second messenger for the hormonal mobilization of intracellular Ca2+ in liver.

1984 • 567 citations

Do GTPases direct membrane traffic in secretion?

1988 • 540 citations

Involvement of GTP-binding “G” proteins in transport through the Golgi stack

1987 • 495 citations

Competitive, reversible, and potent antagonism of inositol 1,4,5-trisphosphate-activated calcium release by heparin.

1988 • 427 citations

Spatial and temporal aspects of cell signalling

1988 • 278 citations

Study of a temperature-sensitive mutant of the ras-related YPT1 gene product in yeast suggests a role in the regulation of intracellular calcium

1988 • 243 citations

Two G-proteins act in series to control stimulus-secretion coupling in mast cells: use of neomycin to distinguish between G-proteins controlling polyphosphoinositide phosphodiesterase and exocytosis.

1987 • 197 citations

Inositol(1,4,5)trisphosphate-promoted Ca2+ release from microsomal fractions of rat liver

1984 • 193 citations

Characterization of inositol 1,4,5-trisphosphate receptors and calcium mobilization in a hepatic plasma membrane fraction.

1988 • 178 citations

Ca2+ release from endoplasmic reticulum is mediated by a guanine nucleotide regulatory mechanism

1986 • 175 citations

Detection of 23-27 kDa GTP-binding proteins in platelets and other cells

1987 • 166 citations

Inositol(1,3,4,5)tetrakisphosphate-induced activation of sea urchin eggs requires the presence of inositol trisphosphate

1987 • 163 citations

Inositol trisphosphate modification of ion transport in rough endoplasmic reticulum.

1985 • 154 citations

GTP enhances inositol trisphosphate‐stimulated Ca²⁺ release from rat liver microsomes

1985 • 148 citations

Influence of inositol 1,4,5-trisphosphate and guanine nucleotides on intracellular calcium release within the N1E-115 neuronal cell line.

1986 • 146 citations

Inositol 1,4,5-trisphosphate and guanine nucleotides activate calcium release from endoplasmic reticulum via distinct mechanisms.

1986 • 140 citations

Calcium modulation of inositol 1,4,5-trisphosphate-induced calcium release from neuroblastoma x glioma hybrid (NG108-15) microsomes.

1986 • 121 citations

Guanosine 5'‐triphosphate releases calcium from rat liver and guinea pig parotid gland endoplasmic reticulum independently of inositol 1,4,5‐trisphosphate

1986 • 113 citations

A fluorescence enhancement assay of cell fusion

1977 • 103 citations

Intracellular calcium uptake activated by GTP. Evidence for a possible guanine nucleotide-induced transmembrane conveyance of intracellular calcium.

1987 • 99 citations

GTP- and inositol 1,4,5-trisphosphate-activated intracellular calcium movements in neuronal and smooth muscle cell lines.

1987 • 94 citations

Calcium entry into the inositol 1,4,5-trisphosphate-releasable calcium pool is mediated by a GTP-regulatory mechanism.

1988 • 78 citations

Presence of guanine nucleotide-binding proteins in a plant hypocytyl microsomal fraction

1988 • 78 citations

Inositol 1,4,5-trisphosphate binds to a specific receptor and releases microsomal calcium in the anterior pituitary gland.

1987 • 75 citations

MgATP-dependent glucose 6-phosphate-stimulated Ca2+ accumulation in liver microsomal fractions. Effects of inositol 1,4,5-trisphosphate and GTP.

1988 • 75 citations

The effect of GTP on inositol 1,4,5-trisphosphate-stimulated Ca2+ efflux from a rat liver microsomal fraction. Is a GTP-dependent protein phosphorylation involved?

1986 • 74 citations

Heparin inhibits the inositol 1,4,5‐trisphosphate‐induced Ca²⁺ release from rat liver microsomes

1988 • 74 citations

Inositol 1,4,5‐trisphosphate and 5′‐GTP induce calcium release from different intracellular pools

1987 • 69 citations

The mechanism of action of GTP on Ca2+ efflux from rat liver microsomal vesicles

1987 • 66 citations

Enhancement of the inositol 1,4,5-trisphosphate-releasable Ca2+ pool by GTP in permeabilized hepatocytes.

1988 • 56 citations

Subcellular compartmentation of guanine nucleotides and functional relationships between the adenine and guanine nucleotide systems in isolated hepatocytes

1979 • 55 citations

GTP- and inositol 1,4,5-trisphosphate-induced release of 45Ca2+ from a membrane store co-localized with pancreatic-islet-cell plasma membrane

1988 • 37 citations

The mechanism of action of GTP on Ca2+ efflux from rat liver microsomal vesicles. Measurement of vesicle fusion by fluorescence energy transfer

1988 • 37 citations

GTP mobilization of Ca2+ from the endoplasmic reticulum of islets. Comparison with myo-inositol 1,4,5-trisphosphate

1987 • 37 citations

GTP requirement for inositol-1,4,5-trisphosphate-induced Ca2+ release from sarcoplasmic reticulum in smooth muscle

1987 • 36 citations

Physiological concentrations of GTP stimulate fusion of the endoplasmic reticulum and the nuclear envelope

1984 • 32 citations

Effect of guanosine triphosphate on the release and uptake of Ca2+ in saponin-permeabilized macrophages and the skeletal-muscle sarcoplasmic reticulum

1987 • 25 citations

GTP-mediated Ca2+ release in rough endoplasmic reticulum. Correlation with a GTP-sensitive increase in membrane permeability

1987 • 25 citations

Polyethylene glycol‐stimulated microsomal GTP hydrolysis

1986 • 21 citations

Properties of a GTP sensitive microdomain in rough microsomes

1987 • 19 citations

Effect of inositol 1,4,5‐trisphosphate and GTP on calcium release from pituitary microsomes

1987 • 18 citations

GTP causes calcium release from a plant microsomal fraction

1989 • 17 citations

The effect of inositol 1,4,5-trisphosphate and GTP on calcium release from rat liver microsomes

1987 • 11 citations

Guanine nucleotide‐induced Ca²⁺ release in permeabilized murine thymocytes

1988 • 7 citations

Possible physiological role of guanosine triphosphate and inositol 1,4,5-trisphosphate in Ca2+ release in macrophages stimulated with chemotactic peptide

1988 • 6 citations

The membrane of the rough endoplasmic reticulum contains cytoplasmically exposed high affinity GTP-binding sites

1987 • 5 citations

Effect of guanosine triphosphate on the release of Ca2+ from intracellular store sites of saponin-treated human peripheral lymphocytes

1987 • 4 citations