The progesterone derivative dydrogesterone abrogates murine stress-triggered abortion by inducing a Th2 biased local immune response

The concepts of stress and stress system disorders. Overview of physical and behavioral homeostasis

1992 • 3,026 citations

Bidirectional cytokine interactions in the maternal-fetal relationship: is successful pregnancy a TH2 phenomenon?

1993 • 2,828 citations

Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities.

1995 • 1,834 citations

Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B.

1990 • 1,510 citations

Physiological Action of Progesterone in Target Tissues*

1997 • 912 citations

Synthesis of T helper 2-type cytokines at the maternal-fetal interface.

1993 • 911 citations

Progesterone favors the development of human T helper cells producing Th2-type cytokines and promotes both IL-4 production and membrane CD30 expression in established Th1 cell clones.

1995 • 731 citations

Interactions between the Hypothalamic-Pituitary-Adrenal Axis and the Female Reproductive System: Clinical Implications

1998 • 692 citations

Reproductive endocrinology, surgery, and technology

1996 • 501 citations

Etiologic factors and subsequent reproductive performance in 195 couples with a prior history of habitual abortion

1984 • 483 citations

Mechanisms of reduced fertility inHoxa-10mutant mice: uterine homeosis and loss of maternalHoxa-10expression

1996 • 480 citations

IL-10 prevents naturally occurring fetal loss in the CBA x DBA/2 mating combination, and local defect in IL-10 production in this abortion-prone combination is corrected by in vivo injection of IFN-τ

2005 • 463 citations

IL-10 prevents naturally occurring fetal loss in the CBA x DBA/2 mating combination, and local defect in IL-10 production in this abortion-prone combination is corrected by in vivo injection of IFN-tau.

1995 • 395 citations

Physiological Action of Progesterone in Target Tissues

1997 • 393 citations

Progesterone-binding Components of Chick Oviduct

1972 • 372 citations

A progesterone-dependent immunomodulatory protein alters the Th1Th2 balance

1996 • 347 citations

T helper 1 response against Leishmania major in pregnant C57BL/6 mice increases implantation failure and fetal resorptions. Correlation with increased IFN-gamma and TNF and reduced IL-10 production by placental cells.

1996 • 345 citations

Antagonist-occupied human progesterone B-receptors activate transcription without binding to progesterone response elements and are dominantly inhibited by A-receptors.

1993 • 330 citations

Pregnancy impairs resistance of C57BL/6 mice to Leishmania major infection and causes decreased antigen-specific IFN-gamma response and increased production of T helper 2 cytokines.

1996 • 311 citations

Abdominal B(AbdB)HoxaGenes: Regulation in Adult Uterus by Estrogen and Progesterone and Repression in Müllerian Duct by the Synthetic Estrogen Diethylstilbestrol (DES)

1998 • 296 citations

Hoxa-10Regulates Uterine Stromal Cell Responsiveness to Progesterone during Implantation and Decidualization in the Mouse

1999 • 295 citations

Cytokine-dependent abortion in CBA x DBA/2 mice is mediated by the procoagulant fgl2 prothrombinase [correction of prothombinase].

1998 • 281 citations

Circadian and sleep-dependent regulation of hormone release in humans.

1999 • 275 citations

A brief review of recent data on some cytokine expressions at the materno-foetal interface which might challenge the classical Th1/Th2 dichotomy

2002 • 270 citations

Differential Uterine Expression of Estrogen and Progesterone Receptors Correlates with Uterine Preparation for Implantation and Decidualization in the Mouse1

1999 • 266 citations

Cutting Edge: Cytokine-Dependent Abortion in CBA × DBA/2 Mice Is Mediated by the Procoagulant fgl2 Prothombinase

1998 • 256 citations

Changes of natural killer cells during acute psychological stress

1993 • 223 citations

Cellular and Molecular Aspects of Implantation

1981 • 216 citations

The A and B forms of the chicken progesterone receptor arise by alternate initiation of translation of a unique mRNA

1987 • 202 citations

Progesterone via Its Receptor Antagonizes the Pro-Inflammatory Activity of Estrogen in the Mouse Uterus1

1999 • 187 citations

Molecular Pathways of Steroid Receptor Action

1992 • 166 citations

The Mechanism of the Inhibitory Effect of Progesterone on Lymphocyte Cytotoxicity: I. Progesterone‐Treated Lymphocytes Release a Substance Inhibiting Cytotoxicity and Prostaglandin Synthesis

1985 • 163 citations

Immunoregulatory effects of a suppressor factor from healthy pregnant women's lymphocytes after progesterone induction

1989 • 142 citations

Evaluation of oestrogen and progesterone receptor expression in uterine mucosal lymphocytes

1996 • 136 citations

Disruption of estrogen signaling does not prevent progesterone action in the estrogen receptor α knockout mouse uterus

1999 • 126 citations

Association of Stressful Life Events with Chromosomally Normal Spontaneous Abortion

1996 • 120 citations

Antagonist-occupied human progesterone B-receptors activate transcription without binding to progesterone response elements and are dominantly inhibited by A-receptors [published erratum appears in Mol Endocrinol 1993 Nov;7(11):1378]

1993 • 118 citations

Psychologic Stress in the Workplace and Spontaneous Abortion

1995 • 117 citations

Suppression of interleukin 8 production by progesterone in rabbit uterine cervix

1994 • 112 citations

Phenotypic and functional studies of leukocytes in human endometrium and endometriosis

1998 • 109 citations

The epidemiology of secondary amenorrhea

1961 • 105 citations

The Antiabortive Effect of Progesterone-Induced Blocking Factor in Mice Is Manifested by Modulating NK Activity

1997 • 103 citations

Stress‐Triggered Abortion: Inhibition of Protective Suppression and Promotion of Tumor Necrosis Factor‐α (TNF‐α) Release as a Mechanism Triggering Resorptions in Mice

1995 • 100 citations

The effect of restraint stress in early pregnancy in mice

1986 • 96 citations

The Expression of a Progesterone‐Induced Immunomodulatory Protein in Pregnancy Lymphocytes

1995 • 94 citations

Soluble Receptors Neutralizing TNF‐α and IL‐1 Block Stress‐Triggered Murine Abortion

1997 • 92 citations

Stress‐Triggered Abortion in Mice Prevented by Alloimmunization

1993 • 92 citations

Localization of pro-inflammatory (IL-12, IL-15) and anti-inflammatory (IL-11, IL-13) cytokines at the foetomaternal interface during murine pregnancy

2001 • 89 citations

Lymphocytic progesterone receptors in normal and pathological human pregnancy

1989 • 83 citations

Murine T Cell Determination of Pregnancy Outcome: I. Effects of Strain, αβ T Cell Receptor, γδ T Cell Receptor, and γδ T Cell Subsets

1997 • 83 citations

Uterine Decidual Response Occurs in Estrogen Receptor-α-Deficient Mice*

1999 • 82 citations

Hoxa-10 Regulates Uterine Stromal Cell Responsiveness to Progesterone during Implantation and Decidualization in the Mouse

1999 • 80 citations

Endometrial leucocytes: expression of steroid hormone receptors.

1998 • 78 citations

Differential Uterine Expression of Estrogen and Progesterone Receptors Correlates with Uterine Preparation for Implantation and Decidualization in the Mouse

1999 • 73 citations

The suppressive effect of progesterone on lymphocyte cytotoxicity: unique progesterone sensitivity of pregnancy lymphocytes

1985 • 73 citations

Expression of Pro‐inflammatory Cytokines in Mouse Blastocysts During Implantation: Modulation by Steroid Hormones

2002 • 71 citations

Work pace control and pregnancy health in a population-based sample of employed women in Norway

1998 • 69 citations

Murine Stress‐triggered Abortion is Mediated by Increase of CD8⁺ TNF‐α⁺ Decidual Cells via Substance P

2001 • 69 citations

Interplay in Vitro Between ACTH, β-Endorphin, and Glucocorticoids in the Modulation of Spontaneous and Lymphokine-Inducible Human Natural Killer (NK) Cell Activity

1993 • 67 citations

Distribution of Progesterone Receptor in Female Mouse Tissues

1999 • 64 citations

Endometrial and myometrial effects of progesterone antagonists in pregnant guinea pigs

1987 • 63 citations

TERMINATION OF EARLY PREGNANCY IN RATS AFTER OVARIECTOMY IS DUE TO IMMEDIATE COLLAPSE OF THE PROGESTERONEDEPENDENT DECIDUA

1973 • 63 citations

Heme Oxygenase is Downregulated in Stress‐Triggered and Interleukin‐12‐Mediated Murine Abortion

2002 • 57 citations

Life Events and Miscarriage

1995 • 55 citations

Early Recognition of Pregnancy by the Maternal Immune System

1998 • 54 citations

A New Class of Hormonally Active Steroids

1960 • 53 citations

Enhancement of the Expression of Progesterone Receptor on Progesterone‐Treated Lymphocytes After Immunotherapy in Unexplained Recurrent Spontaneous Abortion

1996 • 49 citations

Self-Reported Stress and Reproductive Health of Female Lawyers

1997 • 46 citations

Phenotypic characterization of normal human placental mononuclear cells

1993 • 44 citations

An analysis of the uterine lymphocyte-derived hybridoma cell line GWM 1–2 for expression of receptors for estrogen, progesterone and interleukin 2

1996 • 39 citations

Substance P, the Immune System and Inflammation

1989 • 38 citations

Changes in Cytosolic and Nuclear Progesterone Receptors During Pregnancy in Rat Placenta1

1989 • 29 citations

Regulation of the Progesterone Receptor and Estrogen Receptor in Decidua Basalis by Progesterone and Estradiol during Pregnancy1

1998 • 28 citations

STRESS-INDUCED DECREASES IN THE SERUM CONCENTRATION OF PROGESTERONE IN THE PREGNANT BABOON

1978 • 27 citations

Murine Trophoblast Failure and Spontaneous Abortion

1993 • 25 citations

Modulation of the Immune Response by Progesterone‐Induced Lymphocyte Factors

1999 • 22 citations

Progesterone and oestrogen receptors in the decidualized mouse uterus and effects of different types of anti-progesterone treatment

1995 • 20 citations

Flow cytometric analysis of intestinal intraepithelial lymphocytes in a model of immunodeficiency in Wistar rats

2000 • 17 citations

Progesterone and Luteinizing Hormone Secretion Following Stress-Induced Interruption of Constant Estrus in Aged Rats

1985 • 16 citations

Uterine Decidual Response Occurs in Estrogen Receptor- -Deficient Mice

1999 • 14 citations

Inhibition of Dipeptidyl Peptidase IV (DP IV, CD26) Activity Abrogates Stress‐Induced, Cytokine‐Mediated Murine Abortions

2001 • 13 citations

Maintenance of Pregnancy in Ovariectomized Rats With Steriod Analogs and the Reproductive Ability of the Progeny1

1982 • 11 citations

Decidual Cell Function Role of Steroid Hormones and Their Receptors

1981 • 3 citations

Deleted Work

1955 • 0 citations