Binding Properties and Inhibition of Platelet Aggregation by a Monoclonal Antibody to CD31 (PECAM-1)

Platelet endothelial cell adhesion molecule-1 (PECAM-1 / CD31): alternatively spliced, functionally distinct isoforms expressed during mammalian cardiovascular development

1994 • 301 citations

Human platelet size, shape, and related functions in health and disease.

1982 • 265 citations

Migration of monocytes across endothelium and passage through extracellular matrix involve separate molecular domains of PECAM-1.

1995 • 240 citations

Role of platelet membrane glycoprotein IIb-IIIa in agonist-induced tyrosine phosphorylation of platelet proteins.

1990 • 237 citations

On the role of the platelet membrane skeleton in mediating signal transduction. Association of GP IIb-IIIa, pp60c-src, pp62c-yes, and the p21ras GTPase-activating protein with the membrane skeleton.

1993 • 235 citations

The Protein-tyrosine Phosphatase SHP-2 Binds Platelet/Endothelial Cell Adhesion Molecule-1 (PECAM-1) and Forms a Distinct Signaling Complex during Platelet Aggregation

1997 • 215 citations

Leucocyte typing V. White cell differentiation antigens

1995 • 213 citations

Platelet/endothelial cell adhesion molecule-1 (CD31)-mediated cellular aggregation involves cell surface glycosaminoglycans

1993 • 180 citations

Signals from platelet/endothelial cell adhesion molecule enhance the adhesive activity of the very late antigen-4 integrin of human CD34+ hemopoietic progenitor cells.

1994 • 166 citations

The heparin binding PECAM-1 adhesion molecule is expressed by CD34+ hematopoietic precursor cells with early myeloid and B-lymphoid cell phenotypes

1993 • 164 citations

A heterophilic adhesion mechanism for platelet/endothelial cell adhesion molecule 1 (CD31).

1992 • 160 citations

Effects of collagen, ionophore A23187 and prostaglandin E1 on the phosphorylation of specific proteins in blood platelets

1979 • 150 citations

Activation-dependent changes in human platelet PECAM-1: phosphorylation, cytoskeletal association, and surface membrane redistribution.

1992 • 137 citations

Blockade of platelet endothelial cell adhesion molecule-1 protects against myocardial ischemia and reperfusion injury in cats.

1996 • 110 citations

Platelet Endothelial Cell Adhesion Molecule (CD31)

1993 • 90 citations

Role of Platelet-Endothelial Cell Adhesion Molecule (PECAM) in Platelet Adhesion/Aggregation Over Injured but Not Denuded Endothelium In Vivo and Ex Vivo

1996 • 75 citations

Platelet alpha-granule and plasma membrane share two new components: CD9 and PECAM-1

1994 • 66 citations

Biochemical Characterization of PECAM-1 (CD31 Antigen) on Human Platelets

1991 • 65 citations

Anti-CD31 delays platelet adhesion/aggregation at sites of endothelial injury in mouse cerebral arterioles.

1994 • 48 citations

A Monoclonal Antibody, VM64, Reacts with a 130 kDa Glycoprotein Common to Platelets and Endothelial Cells: Heterogeneity in Antibody Binding to Human Aortic Endothelial Cells

1991 • 44 citations

Aggregation-dependent signaling in human platelets is sensitive to protein serine/threonine phosphatase inhibitors

1995 • 20 citations

Mechanism of platelet aggregation induced by a monoclonal antibody requiring Fc portion

1993 • 4 citations

A Monoclonal Antibody That Recognizes a 110-kDa Protein Primarily Located on the Platelet α-Granule, Which Is Translocated to and Upgraded on the Surface Membrane of Platelets upon Activation

1996 • 1 citations

Cited By (0)

Loading...