ras and p53 in the prediction of survival in Dukes' stage B colorectal carcinoma

Genetic Alterations during Colorectal-Tumor Development

1988 • 6,691 citations

Chromosome 17 Deletions and p53 Gene Mutations in Colorectal Carcinomas

1989 • 2,081 citations

Prevalence of ras gene mutations in human colorectal cancers

1987 • 1,866 citations

Detection of high incidence of K-ras oncogenes during human colon tumorigenesis

1987 • 1,074 citations

p53 mutations in colorectal cancer.

1990 • 1,030 citations

Cooperation between gene encoding p53 tumour antigen and ras in cellular transformation

1984 • 761 citations

A multivariate analysis of clinical and pathological variables in prognosis after resection of large bowel cancer

1985 • 467 citations

Identification of occult micrometastases in pericolic lymph nodes of Dukes' B colorectal cancer patients using monoclonal antibodies against cytokeratin and CC49. Correlation with long-term survival

1994 • 413 citations

Mutant p53 DNA clones from human colon carcinomas cooperate with ras in transforming primary rat cells: a comparison of the "hot spot" mutant phenotypes.

1990 • 409 citations

Association of p53 mutations with short survival in colorectal cancer

1994 • 357 citations

Clinical and pathological associations with allelic loss in colorectal carcinoma [corrected]

1989 • 273 citations

Prognostic significance of cytoplasmic p53 oncoprotein in colorectal adenocarcinoma

1992 • 233 citations

Genotypic classification of colorectal adenocarcinoma. Biologic behavior correlates with K-ras-2 mutation type

1993 • 208 citations

Vascular and neural invasion in colorectal carcinoma.Incidence and prognostic significance

1988 • 206 citations

Detection of minority point mutations by modified PCR technique: a new approach for a sensitive diagnosis of tumor-progression markers

1989 • 184 citations

Loss of heterozygosity of p53 gene and p53 protein expression in human colorectal carcinomas.

1991 • 159 citations

Increased p53 protein content of colorectal tumours correlates with poor survival

1992 • 147 citations

K-ras mutation in colorectal cancer: relations to patient age, sex and tumour location

1994 • 137 citations

Urokinase-type plasminogen activator and outcome in Dukes' B colorectal cancer

1994 • 134 citations

Overexpression of p53 and long-term survival in colon carcinoma

1994 • 79 citations

The Mspl polymorphism in intron 6 ofp53(TP53) detected by digestion of PCR products

1991 • 73 citations

Analysis of c-Ki-ras mutations in human colon carcinoma by cell sorting, polymerase chain reaction, and DNA sequencing.

1989 • 51 citations

Survival of Patients With Stage B2 Colon Carcinoma

1989 • 48 citations

High frequency of allelic deletion on chromosome 17p in advanced colorectal cancer

1994 • 46 citations

Histopathologic parameters and DNA analysis in colorectal adenocarcinomas.

1989 • 33 citations