Coiled Bodies and Gems: Janus or Gemini?

Identification and characterization of a spinal muscular atrophy-determining gene

1995 • 3,722 citations

Correlation between severity and SMN protein level in spinal muscular atrophy

1997 • 1,052 citations

Structure and Function in the Nucleus

1998 • 925 citations

A novel nuclear structure containing the survival of motor neurons protein.

1996 • 759 citations

The survival motor neuron protein in spinal muscular atrophy

1997 • 697 citations

Inactivation of the survival motor neuron gene, a candidate gene for human spinal muscular atrophy, leads to massive cell death in early mouse embryos

1997 • 655 citations

The SMN–SIP1 Complex Has an Essential Role in Spliceosomal snRNP Biogenesis

1997 • 650 citations

The Spinal Muscular Atrophy Disease Gene Product, SMN, and Its Associated Protein SIP1 Are in a Complex with Spliceosomal snRNP Proteins

1997 • 636 citations

Fine structural organization of the interphase nucleus in some mammalian cells

1969 • 632 citations

Formation in Vitro of Sperm Pronuclei and Mitotic Chromosomes Induced by Amphibian Ooplasmic Components

1983 • 630 citations

The Neurobiology of Childhood Spinal Muscular Atrophy

1996 • 509 citations

SMN oligomerization defect correlates with spinal muscular atrophy severity

1998 • 493 citations

Transcription-dependent colocalization of the U1, U2, U4/U6, and U5 snRNPs in coiled bodies

1992 • 402 citations

Human autoantibody to a novel protein of the nuclear coiled body: immunological characterization and cDNA cloning of p80-coilin.

1991 • 369 citations

Immunological and ultrastructural studies of the nuclear coiled body with autoimmune antibodies

1991 • 327 citations

Genomic Variation and Gene Conversion in Spinal Muscular Atrophy: Implications for Disease Process and Clinical Phenotype

1997 • 316 citations

When Is a Deletion Not a Deletion? When It Is Converted

1997 • 270 citations

Coiled bodies contain U7 small nuclear RNA and associate with specific DNA sequences in interphase human cells.

1995 • 244 citations

Localisation of rapidly and slowly labelled nuclear RNA as visualized by high resolution autoradiography

1971 • 233 citations

Nuclear distribution of transcription factors in relation to sites of transcription and RNA polymerase II

1997 • 217 citations

Immunocytochemical analysis of the coiled body in the cell cycle and during cell proliferation.

1993 • 201 citations

Nucleoplasmic organization of small nuclear ribonucleoproteins in cultured human cells.

1993 • 162 citations

Is the sphere organelle/coiled body a universal nuclear component?

1995 • 150 citations

Differential interaction of splicing snRNPs with coiled bodies and interchromatin granules during mitosis and assembly of daughter cell nuclei.

1994 • 135 citations

Targeting of U2AF65 to Sites of Active Splicing in the Nucleus

1997 • 124 citations

Cloning, Characterization, and Copy Number of the Murine Survival Motor Neuron Gene: Homolog of the Spinal Muscular Atrophy-Determining Gene

1997 • 116 citations

Inhibition of Protein Dephosphorylation Results in the Accumulation of Splicing snRNPs and Coiled Bodies within the Nucleolus

1997 • 115 citations

The organization of spliceosomal components in the nuclei of higher plants

1995 • 115 citations

Identification and characterization of a sphere organelle protein

1993 • 108 citations

Dynamic Interactions Between Splicing snRNPs, Coiled Bodies and Nucleoli Revealed Using snRNP Protein Fusions to the Green Fluorescent Protein

1998 • 107 citations

U2 and U1 snRNA gene loci associate with coiled bodies

1995 • 105 citations

Human genes encoding U3 snRNA associate with coiled bodies in interphase cells and are clustered on chromosome 17p11.2 in a complex inverted repeat structure

1997 • 89 citations

Spinal muscular atrophy

1997 • 87 citations

Coiled Bodies and U2 snRNA Genes Adjacent to Coiled Bodies Are Enriched in Factors Required for snRNA Transcription

1998 • 86 citations

Of coiled bodies, gems, and salmon

1998 • 74 citations

The cdk7-cyclin H-MAT1 complex associated with TFIIH is localized in coiled bodies.

1997 • 64 citations

Heterogeneity of subcellular localization and electrophoretic mobility of survival motor neuron (SMN) protein in mammalian neural cells and tissues

1998 • 64 citations

Coiled bodies without coilin.

1997 • 56 citations

Transcriptional pulse-chase analysis reveals a role for a novel snRNP-associated protein in the manufacture of spliceosomal snRNPs.

1996 • 56 citations

Catching RNA Polymerase I in Flagranti: Ribosomal Genes Are Transcribed in the Dense Fibrillar Component of the Nucleolus

1995 • 46 citations

Neuronal Differentiation in the Rat Hippocampus Involves a Stage‐specific Reorganization of Subnuclear Structure both In Vivo and In Vitro

1996 • 39 citations

Nucleocytoplasmic transport and snRNP assembly

1993 • 38 citations

Association of RNA with the B and C snurposomes of Xenopus oocyte nuclei

1991 • 28 citations