On mathematical modeling of critical variables in cancer treatment (goals: Better understanding of the past and better planning in the future)

A mathematic model for relating the drug sensitivity of tumors to their spontaneous mutation rate.

1979 • 1,331 citations

Important Advances in Oncology: 1986

1986 • 912 citations

The importance of dose intensity in chemotherapy of metastatic breast cancer.

1984 • 882 citations

EXPERIMENTAL EVALUATION OF POTENTIAL ANTICANCER AGENTS. XIII. ON THE CRITERIA AND KINETICS ASSOCIATED WITH "CURABILITY" OF EXPERIMENTAL LEUKEMIA.

1964 • 763 citations

Rationale for the use of alternating non-cross-resistant chemotherapy.

1982 • 545 citations

Experimental evaluation of potential anticancer agents VIII. Effects of certain nitrosoureas on intracerebral L1210 leukemia.

1963 • 369 citations

Quantitative model for multiple levels of drug resistance in clinical tumors.

1983 • 191 citations

Progress and Perspectives in the Chemotherapy of Acute Leukemia

1965 • 183 citations

Curative cancer chemotherapy.

1985 • 175 citations

Tumor stem cell heterogeneity: implications with respect to classification of cancers by chemotherapeutic effect.

1984 • 64 citations

Concepts for controlling drug-resistant tumor cells.

1980 • 50 citations

The Forty-Year-Old Mutation Theory of Lurla and Delbrück and Its Pertinence to Cancer Chemotherapy

1983 • 41 citations

Advances in cancer research

1984 • 24 citations

The last surviving cancer cell: the chances of killing it.

1966 • 19 citations

Relationship between tumor stem cell heterogeneity and responsiveness to chemotherapy.

1985 • 17 citations

Preoperative (Neoadjuvant) Chemotherapy

1986 • 10 citations

Experimental Adjuvant Chemotherapy: An Overview

1986 • 9 citations

Deveopment of resistance to combinations of six antimetabolites in mice with L1210 leukemia.

1976 • 8 citations

The Last Surviving Cancer Cell: The Chances of Killing It

1970 • 3 citations