Effect of Angiotensin-Converting Enzyme Inhibition and Angiotensin II Receptor Blockers on Cardiac Angiotensin-Converting Enzyme 2

A Novel Angiotensin-Converting Enzyme–Related Carboxypeptidase (ACE2) Converts Angiotensin I to Angiotensin 1-9

2000 • 3,055 citations

A Human Homolog of Angiotensin-converting Enzyme

2000 • 1,970 citations

Angiotensin-converting enzyme 2 is an essential regulator of heart function

2002 • 1,745 citations

Angiotensin-(1–7) is an endogenous ligand for the G protein-coupled receptor Mas

2003 • 1,735 citations

Hydrolysis of Biological Peptides by Human Angiotensin-converting Enzyme-related Carboxypeptidase

2002 • 1,372 citations

ACE2 X-Ray Structures Reveal a Large Hinge-bending Motion Important for Inhibitor Binding and Catalysis

2004 • 700 citations

Evaluation of angiotensin-converting enzyme (ACE), its homologue ACE2 and neprilysin in angiotensin peptide metabolism

2004 • 599 citations

Upregulation of Angiotensin-Converting Enzyme 2 After Myocardial Infarction by Blockade of Angiotensin II Receptors

2004 • 561 citations

Counterregulatory Actions of Angiotensin-(1-7)

1997 • 507 citations

Cardiac Actions of Angiotensin II: Role of an Intracardiac Renin-Angiotensin System

1992 • 505 citations

The Cardiac Renin-Angiotensin System

1999 • 395 citations

Angiotensin-(1–7) Attenuates the Development of Heart Failure After Myocardial Infarction in Rats

2002 • 323 citations

Increased Angiotensin-(1-7)–Forming Activity in Failing Human Heart Ventricles

2003 • 311 citations

Metabolism of Angiotensin-(1–7) by Angiotensin-Converting Enzyme

1998 • 290 citations

Angiotensin-(1-7): Cardioprotective Effect in Myocardial Ischemia/Reperfusion

2001 • 240 citations

Effects of captopril related to increased levels of prostacyclin and angiotensin-(1-7) in essential hypertension

1996 • 229 citations

Vasodepressor Actions of Angiotensin-(1–7) Unmasked During Combined Treatment With Lisinopril and Losartan

1998 • 228 citations

Angiotensin-(1–7) Contributes to the Antihypertensive Effects of Blockade of the Renin-Angiotensin System

1998 • 224 citations

A model of the ACE2 structure and function as a SARS-CoV receptor

2003 • 209 citations

Cardiac Angiotensin II Formation in the Clinical Course of Heart Failure and Its Relationship With Left Ventricular Function

2001 • 204 citations

Angiotensin-Converting Enzyme-2 (ACE2): Comparative Modeling of the Active Site, Specificity Requirements, and Chloride Dependence

2003 • 182 citations

Substrate-Based Design of the First Class of Angiotensin-Converting Enzyme-Related Carboxypeptidase (ACE2) Inhibitors

2002 • 178 citations

ACEH/ACE2 is a novel mammalian metallocarboxypeptidase and a homologue of angiotensin-converting enzyme insensitive to ACE inhibitors

2002 • 176 citations

Cardiac Angiotensin-(1-7) in Ischemic Cardiomyopathy

2003 • 132 citations

Enhanced Renal Immunocytochemical Expression of ANG-(1-7) and ACE2 During Pregnancy

2003 • 127 citations

Pathways for angiotensin-(1—7) metabolism in pulmonary and renal tissues

2000 • 123 citations

Angiotensin-(1-7) Formation in the Intact Human Heart

2003 • 116 citations

Evidence against a major role for angiotensin converting enzyme-related carboxypeptidase (ACE2) in angiotensin peptide metabolism in the human coronary circulation

2004 • 92 citations

Effects of Angiotensin-Converting Enzyme Inhibition on Angiotensin and Bradykinin Peptides in Rats with Myocardial Infarction

1996 • 44 citations

Release of Preformed Ang II from Myocytes Mediates Angiotensinogen and ET-1 Gene Overexpression In Vivo via AT1 Receptor

2002 • 25 citations