The interaction between MK-801 and receptors for : Functional consequences

Elevation of the Extracellular Concentrations of Glutamate and Aspartate in Rat Hippocampus During Transient Cerebral Ischemia Monitored by Intracerebral Microdialysis

1984 • 2,884 citations

Excitatory Amino Acid Transmitters

1981 • 2,488 citations

The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist.

1986 • 1,814 citations

Blockade of N -Methyl-D-Aspartate Receptors May Protect Against Ischemic Damage in the Brain

1984 • 1,689 citations

Distribution of N-methyl-D-aspartate-sensitive L-[3H]glutamate-binding sites in rat brain

1985 • 1,294 citations

Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid

1986 • 1,283 citations

Hypoglycemia-Induced Neuronal Damage Prevented by an N -Methyl-D-Aspartate Antagonist

1985 • 673 citations

Possible Therapeutic Applications of Antagonists of Excitatory Amino acid Neurotransmitters

1985 • 558 citations

Anticonvulsant activity of (+)‐5‐methyl‐10, 11‐dihydro‐5H‐dibenzo[a, d]cyclohepten‐5, 10‐imine (MK‐801), a substance with potent anticonvulsant, central sympathomimetic, and apparent anxiolytic properties

1982 • 496 citations

Quantitative studies on some antagonists of N‐methyl D‐aspartate in slices of rat cerebral cortex

1985 • 487 citations

The chemical excitation of spinal neurones by certain acidic amino acids

1960 • 484 citations

Chemical Excitation of Spinal Neurones

1959 • 266 citations

Intracellular calcium accumulation in rat hippocampus during seizures induced by bicuculline orl-allylglycine

1983 • 168 citations

Excitatory amino acids and central synaptic transmission

1984 • 139 citations

Restoration of shock‐suppressed behavior by treatment with (+)‐5‐methyl‐10,11‐dihydro‐5H‐dibenzo[a, d]cyclohepten‐5, 10‐imine (MK‐801), a substance with potent anticonvulsant, central sympathomimetic, and apparent anxiolytic properties

1982 • 137 citations

Cell damage in epilepsy and the role of calcium in cytotoxicity.

1986 • 81 citations

Actions of excitatory amino acids and their antagonism

1974 • 30 citations

NEURONAL ALTERATIONS IN HIPPOCAMPUS FOLLOWING SEVERE HYPOGLYCAEMIA: A LIGHT MICROSCOPIC AND ULTRASTRUCTURAL STUDY IN THE RAT

1986 • 24 citations