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Transforming growth factor-β is a potent inhibitor of IL-1 induced protease activity and cartilage proteoglycan degradation

Data up to Jan 2025

Published1988
Citations134
References24

Total Citations Per Year

Abstract

References (24)

Biology of interleukin 1

1988 • 1,547 citations

Some recent advances in the chemistry and biology of transforming growth factor-beta.

1987 • 1,308 citations

There is more than one interleukin 1

1986 • 1,226 citations

The TGF-β family of growth and differentiation factors

1987 • 675 citations

Biochemical changes in the cartilage of the knee in experimental and natural osteoarthritis in the dog

1976 • 408 citations

Aggregation of Cartilage Proteoglycans

1974 • 393 citations

Transforming growth factor-beta is a potent immunosuppressive agent that inhibits IL-1-dependent lymphocyte proliferation.

1988 • 392 citations

The role of link-protein in the structure of cartilage proteoglycan aggregates

1979 • 374 citations

The Effect of Synovial Tissue on the Breakdown of Articular Cartilage in Organ Culture

1977 • 312 citations

A cartilage catabolic factor from synovium

1979 • 246 citations

Transforming growth factor‐beta modulates the expression of osteoblast and chondroblast phenotypes in vitro

1988 • 216 citations

SEQUENCES OF INTEREST: Complementary Deoxyribonucleic Acid Cloning of a Novel Transforming Growth Factor-β Messenger Ribonucleic Acid from Chick Embryo Chondrocytes

1988 • 191 citations

Neutral proteases capable of proteoglycan digesting activity in osteoarthritic and normal human articular cartilage

1984 • 166 citations

Transforming growth factors and control of neoplastic cell growth

1987 • 141 citations

Synthesis of collagenase and neutral proteases by articular chondrocytes: Stimulation by a macrophage-derived factor

1978 • 132 citations

The isolation and characterization of the link proteins from proteoglycan aggregates of bovine nasal cartilage

1979 • 130 citations

Expression of IL-1 genes in human and bovine chondrocytes: A mechanism for autocrine control of cartilage matrix degradation

1986 • 113 citations

The heterogeneity of link proteins isolated from human articular cartilage proteoglycan aggregates.

1982 • 84 citations

Correlation between articular cartilage collagenase activity and osteoarthritis

1978 • 67 citations

Aggregation of cartilage proteoglycans. Ii. Evidence for the presence of a hyaluronate‐binding region on proteoglycans from osteoarthritic cartilage

1976 • 65 citations

Suppression of immune cell function in vitro by recombinant human transforming growth factor-β

1988 • 48 citations

Characterization of stage-specific antigens of infective larvae of the filarial parasite Brugia malayi.

1988 • 24 citations

Interleukin-1-induced alterations in proteoglycan metabolism and matrix assembly

1988 • 23 citations

Pig Interleukin-1 (catabolin) Induces Resorption of Cartilage Proteoglycan and Prevents Synthesis of Proteoglycan and Collagen

1985 • 22 citations

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Transforming growth factor-β is a potent inhibitor of IL-1 induced protease activity and… (1988) – Biochemical and Biophysical Research Communications | Metascience Observatory Explorer