The Thyroid Axis and Depression

Enhancement of Imipramine Antidepressant Activity by Thyroid Hormone

1969 • 392 citations

Hypercortisolemia and hippocampal changes in depression

1993 • 284 citations

Pharmacology of Antidepressants—Characteristics of the Ideal Drug

1994 • 252 citations

Myxoedematous Madness

1949 • 248 citations

Rapid Cycling Bipolar Affective Disorder

1990 • 247 citations

Kinetic evidence suggesting two mechanisms for iodothyronine 5'-deiodination in rat cerebral cortex.

1982 • 235 citations

Carrier-Mediated Transport of Thyroid Hormones through the Rat Blood-Brain Barrier: Primary Role of Albumin-Bound Hormone*

1979 • 151 citations

Antithyroid antibodies in depressed patients

1985 • 148 citations

The Role of Thyroid Hormone Deiodination in the Regulation of Hypothalamo-Pituitary Function

1984 • 125 citations

A Controlled Comparison of Adjuvant Lithium Carbonate or Thyroid Hormone in Clomipramine-Treated Patients with Obsessive-Compulsive Disorder

1991 • 116 citations

Changes in adrenal status affect hypothalamic thyrotropin-releasing hormone gene expression in parallel with corticotropin-releasing hormone.

1995 • 112 citations

Failure of T3 to potentiate tricyclic antidepressant response

1987 • 111 citations

Hormonal Potentiation of Imipramine and ECT in Primary Depression

1972 • 103 citations

Splicing of juvenile and adult tau mRNA variants is regulated by thyroid hormone.

1991 • 84 citations

Thyroid hormone and the TRH stimulation test in refractory depression.

1984 • 81 citations

Nocturnal Serum Thyrotropin (TSH) Surge and the TSH Response to TSH-Releasing Hormone: Dissociated Behavior in Untreated Depressives*

1990 • 79 citations

The role of glucocorticoids in the regulation of thyrotropin

1989 • 76 citations

Treatment of imipramine-resistant recurrent depression: I. An open clinical trial of adjunctive L-triiodothyronine.

1989 • 65 citations

Serum thyrotropin in hospitalized psychiatric patients: Evidence for hyperthyrotropinemia as measured by an ultrasensitive thyrotropin assay

1990 • 63 citations

Review: Thyroid function in psychiatric illness

1990 • 60 citations

CSF transthyretin in patients with depression

1993 • 58 citations

The influence of desipramine on thyroid hormone metabolism in rat brain.

1994 • 58 citations

Thyroid failure in the elderly. Microsomal antibodies as discriminant for therapy

1987 • 51 citations

TREATMENT OF PSYCHIATRIC DISORDERS WITH TRIIODOTHYRONINE

1958 • 47 citations

Glucocorticoids stimulate thyrotropin-releasing hormone gene expression in cultured hypothalamic neurons.

1995 • 43 citations

Thyroid Hormone Treatment of Depression

1995 • 42 citations

CSF triiodothyronine (rT3) levels in patients with affective disorders.

1983 • 36 citations

THE APPLICATION OF TRIIODOTHYRONINE IN THE TREATMENT OF MENTAL DISORDERS

1958 • 35 citations

Feedback Effectiveness of Periodic Versus Constant Triiodothyronine Replacement*

1980 • 35 citations

Triiodothyronine Potentiation of Fluoxetine in Depressed Patients^*

1992 • 34 citations

T3 augmentation of antidepressant treatment in T4-replaced thyroid patients.

1992 • 33 citations

Does Thyroid Hormone Have a Role as Adjunctive Therapy in Depression?1

1996 • 31 citations

The Interface Between Thyroid Hormones and Psychiatry

1996 • 31 citations

A Perspective on the Thyroid and Depression^*

1990 • 31 citations

Augmentation regimens for depression.

1991 • 28 citations

Thyroid Hormone Supplementation of Fluoxetine in the Treatment of Major Depression

1991 • 27 citations

Inhibition of thyroxine 5′-deiodination type II in cultured human placental cells by cortisol, insulin, 3′,5′-cyclic adenosine monophosphate, and butyrate

1988 • 26 citations

Thyrotropin (TSH) and thyroid hormone concentrations during partial sleep deprivation in patients with major depressive disorder

1990 • 24 citations

Activation of thyrotropin-releasing hormone gene expression in cultured fetal diencephalic neurons by differentiating agents.

1996 • 18 citations

Hippocampal Input to the Hypothalamus Inhibits Thyrotrophin and Thyrotrophin-Releasing Hormone Gene Expression

1993 • 18 citations

Subclinical hypothyroidism

1987 • 16 citations

Comparison of Thyroid Function between Responders and Nonresponders to Thyroid Hormone Supplementation in Depression

1992 • 10 citations

Activation of thyrotropin-releasing hormone gene expression in cultured fetal diencephalic neurons by differentiating agents

1996 • 9 citations

Thyrotropin-releasing hormone and corticotropin-releasing hormone-- what's the message?

1995 • 5 citations