Oligodendrocytes and the control of myelination in vivo: new insights from the rat anterior medullary velum

Cell death and control of cell survival in the oligodendrocyte lineage

1992 • 1,331 citations

Multiple extracellular signals are required for long-term oligodendrocyte survival

1993 • 707 citations

Proliferation of oligodendrocyte precursor cells depends on electrical activity in axons

1993 • 622 citations

Co-localization of NG2 proteoglycan and PDGF ?-receptor on O2A progenitor cells in the developing rat brain

1996 • 620 citations

FGF modulates the PDGF-driven pathway of oligodendrocyte development

1990 • 586 citations

Cooperation between two growth factors promotes extended self-renewal and inhibits differentiation of oligodendrocyte-type-2 astrocyte (O-2A) progenitor cells.

1990 • 573 citations

Oligodendrocyte Population Dynamics and the Role of PDGF In Vivo

1998 • 484 citations

PDGF receptors in the rat CNS: during late neurogenesis, PDGF alpha-receptor expression appears to be restricted to glial cells of the oligodendrocyte lineage

1992 • 435 citations

Increased expression of the NG2 chondroitin-sulfate proteoglycan after brain injury

1994 • 395 citations

Isolation and Characterization of Myelin

1977 • 389 citations

PDGF A-chain gene is expressed by mammalian neurons during development and in maturity

1991 • 360 citations

Molecular dissection of the myelinated axon

1993 • 352 citations

Myelinated nerve fibres in the CNS

1993 • 351 citations

Response of the oligodendrocyte progenitor cell population (defined by NG2 labelling) to demyelination of the adult spinal cord

1998 • 342 citations

Myelin-associated glycoprotein, a member of the L2/HNK-1 family of neural cell adhesion molecules, is involved in neuron-oligodendrocyte and oligodendrocyte-oligodendrocyte interaction.

1987 • 335 citations

Induction of sodium channel clustering by oligodendrocytes

1997 • 328 citations

Central remyelination restores secure conduction

1979 • 316 citations

Dependence of Nodal Sodium Channel Clustering on Paranodal Axoglial Contact in the Developing CNS

1999 • 315 citations

Rat optic nerve: Electrophysiological, pharmacological and anatomical studies during development

1982 • 281 citations

The brain fibroblast growth factor (FGF) is localized in neurons

1986 • 276 citations

Development and differentiation of glial precursor cells in the rat cerebellum

1993 • 276 citations

Peripheral nerve explants grafted into the vitreous body of the eye promote the regeneration of retinal ganglion cell axons severed in the optic nerve

1996 • 263 citations

Development of macroglial cells in rat cerebellum II. An in situ immunohistochemical study of oligodendroglial lineage from precursor to mature myelinating cell

1988 • 255 citations

Oligodendroglial progenitors labeled with the O4 antibody persist in the adult rat cerebral cortex in vivo

1997 • 255 citations

In situ demonstration of mature oligodendrocytes and their processes: An immunocytochemical study with a new monoclonal antibody, Rip

1989 • 252 citations

A quantitative study of morphological changes accompanying the initiation and progress of myelin production in the dorsal funiculus of the rat spinal cord

1971 • 237 citations

Interaction between NG2 proteoglycan and PDGF ?-receptor on O2A progenitor cells is required for optimal response to PDGF

1996 • 236 citations

Fibroblast growth factor is a mitogen for oligodendrocytes in vitro

1985 • 227 citations

Oligodendrocyte progenitors isolated directly from developing telencephalon at a specific phenotypic stage: myelinogenic potential in a defined environment

1989 • 225 citations

PDGF receptors on cells of the oligodendrocyte-type-2 astrocyte (O-2A) cell lineage

1989 • 224 citations

Isolation and Characterization of Myelin

1984 • 223 citations

Astrocytic neuroglial cells, oligodendrocytes and microgliacytes in the spinal cord of the toad

1968 • 222 citations

Cells expressing the NG2 antigen contact nodes of Ranvier in adult CNS white matter

1999 • 211 citations

Light and electron microscopic localization of a cell surface antigen (NG2) in the rat cerebellum: association with smooth protoplasmic astrocytes

1987 • 188 citations

Plasticity of developing cerebellar cells in vitro studied with antibodies against the NG2 antigen

1987 • 183 citations

THE RESTORATION OF CONDUCTION BY CENTRAL REMYELINATION

1981 • 174 citations

Glial Cell Mitogens bFGF and PDGF Differentially Regulate Development of O4+GalC- Oligodendrocyte Progenitors

1993 • 170 citations

Myelin‐Associated Glycoprotein Location and Potential Functions^a

1990 • 167 citations

Regulation of FGF Receptors in the Oligodendrocyte Lineage

1996 • 160 citations

The timely expression of myelin basic protein gene in cultured rat brain oligodendrocytes is independent of continuous neuronal influences

1985 • 158 citations

Development and maturation of central nervous system myelin: Comparison of immunohistochemical localization of proteolipid protein and basic protein in myelin and oligodendrocytes

1982 • 149 citations

The perinodal astrocyte

1988 • 148 citations

Development of macroglial cells in rat cerebellum. I. Use of antibodies to follow earlyin vivo development and migration of oligodendrocytes

1988 • 147 citations

PDGF and intracellular signaling in the timing of oligodendrocyte differentiation.

1989 • 146 citations

Localization of insulin-like growth factor-1 mRNA in murine central nervous system during postnatal development

1991 • 144 citations

Proliferation and differentiation of O4⁺ oligodendrocytes in postnatal rat cerebellum: Analysis in unfixed tissue slices using anti‐glycolipid antibodies

1992 • 139 citations

Morphology of astrocytes and oligodendrocytes during development in the intact rat optic nerve

1993 • 139 citations

Relation between myelin sheath thickness and axon size in spinal cord white matter of some vertebrate species

1978 • 135 citations

Current concepts of PLP and its role in the nervous system

1998 • 134 citations

Biochemical subtypes of oligodendrocyte in the anterior medullary velum of the rat as revealed by the monoclonal antibody rip

1995 • 133 citations

FGF-2 converts mature oligodendrocytes to a novel phenotype

1997 • 128 citations

Relation between axons and oligodendroglial cells during initial myelination I. The glial unit

1990 • 124 citations

Morphological characteristics of central demyelination and remyelination: A single‐fiber study

1977 • 106 citations

Specificity in central myelination: evidence for local regulation of myelin thickness

1984 • 103 citations

Astrocytic neuroglial cells, oligodendrocytes and microgliacytes in the spinal cord of the toad

1967 • 102 citations

Rat optic nerve: Freeze-fracture studies during development of myelinated axons

1982 • 102 citations

Morphological heterogeneity of rat oligodendrocytes: Oligodendrocytes: Electron microscopic studies on serial sections

1994 • 98 citations

In vivo actions of fibroblast growth factor-2 and insulin-like growth factor-I on oligodendrocyte development and myelination in the central nervous system

1999 • 95 citations

Localization of basic fibroblast growth factor-like immunoreactivity in the rat brain

1992 • 90 citations

Astrocyte associations with nodes of Ranvier: ultrastructural analysis of HRP-filled astrocytes in the mouse optic nerve

1994 • 89 citations

Recent Advances in Neuropathology

1983 • 88 citations

Dying-back oligodendrogliopathy: A late sequel of myelin-associated glycoprotein deficiency

1997 • 84 citations

Immuno-ultrastructural localization of sodium channels at nodes of Ranvier and perinodal astrocytes in rat optic nerve

1989 • 79 citations

Distribution of sodium channels in chronically demyelinated spinal cord axons: immuno-ultrastructural localization and electrophysiological observations

1991 • 74 citations

Oligodendrocyte survival in Wallerian degeneration

1990 • 72 citations

Rat oligodendrocytes and astrocytes preferentially express fibroblast growth factor receptor-2 and -3 mRNAs

1996 • 71 citations

Cellular reaction to an acute demyelinating/remyelinating lesion of the rat brain stem: Localisation of GD3 ganglioside immunoreactivity

1993 • 66 citations

Noncoordinate regulation of myelinogenic parameters in primary cultures of dissociated fetal rat brain

1981 • 66 citations

Basic fibroblast growth factor down‐regulates myelin basic protein gene expression and alters myelin compaction of mature oligodendrocytes in vitro

1995 • 64 citations

Conduction properties of central demyelinated and remyelinated axons, and their relation to symptom production in demyelinating disorders

1994 • 62 citations

Relationship between myelin sheath diameter and internodal length in axons of the anterior medullary velum of the adult rat

1995 • 61 citations

The relationship between developing oligodendrocyte units and maturing axons during myelinogenesis in the anterior medullary velum of neonatal rats.

1997 • 58 citations

Regulation of Oligodendrocyte Development by Insulin‐Like Growth Factors and Cyclic Nucleotides^a

1990 • 54 citations

Effect of optic nerve transection upon myelin protein gene expression by oligodendrocytes: evidence for axonal influences on gene expression

1990 • 52 citations

Localisation of motoneurons supplying the extra-ocular muscles of the rat using horseradish peroxidase and fluorescent double labelling.

1983 • 52 citations

Use of a rat Y chromosome probe to determine the long-term survival of glial cells transplanted into areas of CNS demyelination.

1997 • 51 citations

Quantitative examination of internodal length of remyelinated nerve fibres in the central nervous system

1981 • 51 citations

Axon-glial relationships in the anterior medullary velum of the adult rat

1995 • 50 citations

Glial cells in transected optic nerves of immature rats. II. An immunohistochemical study

1996 • 48 citations

Role of glial cells in the differentiation and function of myelinated axons

1988 • 47 citations

PDGF-α Receptor and Myelin Basic Protein mRNAs Are Not Coexpressed by Oligodendrocytesin Vivo:A Doublein SituHybridization Study in the Anterior Medullary Velum of the Neonatal Rat

1997 • 44 citations

Node-like axonal specialisations along demyelinated central nerve fibres: Ultrastructural observations

1983 • 42 citations

Differential expression of the L- and S-isoforms of myelin associated glycoprotein (MAG) in oligodendrocyte unit phenotypes in the adult rat anterior medullary velum.

1998 • 41 citations

Morphologic analysis of axo-glial membrane specializations in the demyelinated central nervous system

1980 • 39 citations

Platelet-derived growth factor delays oligodendrocyte differentiation and axonal myelination in vivo in the anterior medullary velum of the developing rat

1997 • 39 citations

Endocytic depletion of L-MAG from CNS myelin in quaking mice.

1995 • 39 citations

Topographic variations in rat brain oligodendrocyte morphology elucidated by injection of Lucifer Yellow in fixed tissue slices

1996 • 37 citations

Axon-myelin sheath relations of oligodendrocyte unit phenotypes in the adult rat anterior medullary velum.

1998 • 37 citations

Dependence of axolemmal differentiation on contact with glial cells in chronically demyelinated lesions of cat spinal cord

1985 • 29 citations

The central-peripheral transitional regions of cranial nerves. Trochlear and abducent nerves.

1988 • 28 citations

The injury response of nerve fibers in the anterior medullary velum of the adult rat

1984 • 25 citations

Myelin sheath thickness in the CNS is regulated near the axon

1983 • 24 citations

Canine oligodendrocytes undergo morphological changes in response to basic fibroblast growth factor (bFGF) in vitro

1995 • 20 citations

Cellular Responses to Penetrating CNS Injury

1998 • 19 citations

Differential regulation of cerebroside sulfotransferase and 2′,3′‐cyclic nucleotide 3′‐phosphodiesterase by basic fibroblast growth factor in relation to proliferation in rat oligodendrocyte cultures

1992 • 18 citations

Clonazepam and branchial myoclonus

1977 • 18 citations

Axon-glial relations during regeneration of axons in the adult rat anterior medullary velum.

1998 • 18 citations

Induction of myelin-associated glycoprotein expression through neuron–oligodendrocyte contact

1997 • 16 citations

Regeneration of axons into the trochlear rootlet after anterior medullary lesions in the rat is specific for ipsilateral IVth nerve motoneurones

1994 • 12 citations

The anterior medullary velum and its involvement during autoimmune demyelination

1986 • 6 citations

Regeneration of nerve fibres in the anterior medullary velum of neonatal and weanling rats

1990 • 6 citations

Techniques for the study of the blood-brain barrier in non-mammalian species

1988 • 3 citations

Axon-oligodendrocyte relations in the anterior medullary velum of the rat brain.

1997 • 1 citations