Arylsulfonamidothiazoles as a New Class of Potential Antidiabetic Drugs. Discovery of Potent and Selective Inhibitors of the 11β-Hydroxysteroid Dehydrogenase Type 1

11β-Hydroxysteroid dehydrogenase type 1 knockout mice show attenuated glucocorticoid-inducible responses and resist hyperglycemia on obesity or stress

1997 • 851 citations

Hypertension in mice lacking 11β-hydroxysteroid dehydrogenase type 2

1999 • 282 citations

Type 1 11β-Hydroxysteroid Dehydrogenase Mediates Glucocorticoid Activation and Insulin Release in Pancreatic Islets

2000 • 117 citations

Selective inhibition of human type 1 11β‐hydroxysteroid dehydrogenase by synthetic steroids and xenobiotics

1998 • 61 citations

The metabolism of 9α-fluorinated steroids in the human kidney

1996 • 13 citations