Reorganization of Neuronal Connections Following CNS Trauma: Principles and Experimental Paradigms

The Nerve Growth Factor 35 Years Later

1987 • 3,107 citations

Degeneration and Regeneration of the Nervous System.

1929 • 2,924 citations

Axonal Elongation into Peripheral Nervous System "Bridges" After Central Nervous System Injury in Adult Rats

1981 • 1,679 citations

Nerve growth factor promotes survival of septal cholinergic neurons after fimbrial transections

1986 • 1,458 citations

The Axon Reaction: A Review of the Principal Features of Perikaryal Responses to Axon Injury

1971 • 1,112 citations

Continuous infusion of nerve growth factor prevents basal forebrain neuronal death after fimbria fornix transection.

1986 • 1,063 citations

Axons from CNS neurones regenerate into PNS grafts

1980 • 928 citations

Reconstruction of the nigrostriatal dopamine pathway by intracerebral nigral transplants

1979 • 830 citations

Neuronal plasticity in the septal nuclei of the adult rat

1969 • 818 citations

Dopamine Receptor Binding Enhancement Accompanies Lesion-Induced Behavioral Supersensitivity

1977 • 716 citations

Intraspinal Sprouting of Dorsal Root Axons

1958 • 609 citations

Axonal regeneration and synapse formation in the superior colliculus by retinal ganglion cells in the adult rat

1987 • 587 citations

Early Lesions of Superior Colliculus: Factors Affecting the Formation of Abnormal Retinal Projections; pp. 73–90

1973 • 548 citations

Synapse replacement in the nervous system of adult vertebrates.

1981 • 545 citations

Grafting Genetically Modified Cells to the Damaged Brain: Restorative Effects of NGF Expression

1988 • 508 citations

A quantitative investigation of the development of collateral reinnervation after partial deafferentation of the septal nuclei

1973 • 496 citations

Brain Injury Causes a Time-Dependent Increase in Neuronotrophic Activity at the Lesion Site

1982 • 477 citations

Plasticity of Hippocampal Circuitry in Alzheimer's Disease

1985 • 457 citations

An electron microscopic study of lesion-induced synaptogenesis in the dentate gyrus of the adult rat. I. Magnitude and time course of degeneration

1976 • 453 citations

Induced acetylcholinesterase-rich layer in rat dentate gyrus following entorhinal lesions

1972 • 451 citations

Extensive elongation of axons from rat brain into peripheral nerve grafts

1982 • 436 citations

Nerve growth factor (NGF) in the rat CNS: Absence of specific retrograde axonal transport and tyrosine hydroxylase induction in locus coeruleus and substantia nigra

1979 • 422 citations

Septal transplants restore maze learning in rats with fornix-fimbria lesions

1982 • 414 citations

The development of the acoustico‐vestibular centres in the chick embryo in the absence of the afferent root fibers and of descending fiber tracts

1949 • 403 citations

An electron microscopic study of lesion-induced synaptogenesis in the dentate gyrus of the adult rat. II. Reappearance of morphologically normal synaptic contacts

1976 • 385 citations

Selective reinnervation of hippocampal area CA1 and the fascia dentata after destruction of CA3-CA4 afferents with kainic acid

1980 • 380 citations

Restitution of function and collateral sprouting in the cat spinal cord: The partially hemisected animal

1974 • 376 citations

Regeneration of monoaminergic and cholinergic neurons in the mammalian central nervous system

1979 • 374 citations

Functional and structural changes in mammalian sympathetic neurones following interruption of their axons.

1975 • 348 citations

The formation and transformation of the perceptual world

1964 • 322 citations

Collateral Nerve Regeneration

1953 • 319 citations

SPROUTING AS A CAUSE OF SPASTICITY

1958 • 302 citations

Axonal regeneration in the rat sciatic nerve: Effect of a conditioning lesion and of dbcAMP

1977 • 289 citations

Restitution of function and collateral sprouting in the cat spinal cord: The deafferented animal

1974 • 286 citations

Mechanisms of Functional Recovery Following Lesions of Visual Cortex or Superior Colliculus in Neonate and Adult Hamsters

1970 • 275 citations

New Neuronal Growth Factors

1984 • 269 citations

Reformation of the severed septohippocampal cholinergic pathway in the adult rat by transplanted septal neurons

1977 • 264 citations

Intraspinal transplantation of embyronic spinal cord tissue in neonatal and adult rats

1986 • 262 citations

Functional reinnervation of the neostriatum in the adult rat by use of intraparenchymal grafting of dissociated cell suspensions from the substantia nigra

1980 • 259 citations

Synaptic Adjustment after Deafferentation of the Superior Colliculus of the Rat

1971 • 259 citations

The process of reinnervation in the dentate gyrus of the adult rat: A quantitative electron microscopic analysis of terminal proliferation and reactive synaptogenesis

1983 • 252 citations

Modulatory Actions of Neurotransmitters

1979 • 252 citations

Regeneration of the septohippocampal pathways in adult rats is promoted by utilizing embryonic hippocampal implants as bridges

1981 • 249 citations

Lesion-Induced Neuronal Plasticity in Sensorimotor Systems

1981 • 247 citations

Transneuronal cell degeneration in the auditory relay nuclei of the cat.

1962 • 242 citations

EXPERIMENTAL DEGENERATION IN THE CEREBRAL CORTEX.

1964 • 237 citations

Behavioral correlates of denervation and reinnervation of the hippocampal formation of the rat: Recovery of alternation performance following unilateral entorhinal cortex lesions

1977 • 232 citations

Neurotrophic Factors

1985 • 230 citations

Afferent influences on brain stem auditory nuclei of the chicken: Neuron number and size following cochlea removal

1985 • 229 citations

Neural tissue transplants rescue axotomized rubrospinal cells from retrograde death

1986 • 227 citations

Mirror movements after childhood hemiparesis

1978 • 217 citations

Sprouting of optic tract projections in the brain stem of the rat

1966 • 216 citations

Peripheral nerve autografts to the rat spinal cord: Studies with axonal tracing methods

1982 • 214 citations

Developmental differences in post-lesion axonal growth in the hippocampus

1973 • 209 citations

Growth of a new fiber projection in the brain of adult rats: Re-innervation of the dentate gyrus by the contralateral entorhinal cortex following ipsilateral entorhinal lesions

1974 • 206 citations

Grafting genetically modified cells to the brain: Possibilities for the future

1987 • 206 citations

Recovery from Brain Damage

1978 • 203 citations

A light and electron microscopic study of regrowing pyramidal tract fibers

1982 • 200 citations

Transneuronal cell degeneration in the lateral geniculate nucleus of the macaque monkey.

1960 • 199 citations

Spine Loss and Regrowth in Hippocampus following Deafferentation

1974 • 196 citations

Functional Development of Grafted Vasopressin Neurons

1980 • 193 citations

Cross-species neural grafting in a rat model of Parkinson's disease

1982 • 192 citations

Decline in reactive fiber growth in the dentate gyrus of aged rats compared to young adult rats following entorhinal cortex removal

1980 • 187 citations

Functional reactivation of the deafferented neostriatum by nigral transplants

1981 • 187 citations

Regrowth of Severed Axons in the Neonatal Central Nervous System: Establishment of Normal Connections

1979 • 182 citations

Quantitative electron microscopy on the injured hypoglossal nucleus in the rat

1973 • 179 citations

Dendritic reorganization in the denervated dentate gyrus of the rat following entorhinal cortical lesions: A Golgi and electron microscopic analysis

1983 • 178 citations

Fetal Brain Transplant: Reduction of Cognitive Deficits in Rats with Frontal Cortex Lesions

1983 • 175 citations

The possibility of structural and functional restitution after spinal cord injury. A review

1977 • 168 citations

Electron microscopy of experimental degeneration in the avian optic tectum.

1962 • 166 citations

Re-establishment of electrophysiologically functional entorhinal cortical input to the dentate gyrus deafferented by ipsilateral entorhinal lesions: Innervation by the contralaeral entorhinal cortex

1973 • 164 citations

Transplantation of brain tissue in the brain of rat. I. Growth characteristics of neocortical transplants from embryos of different ages

1980 • 162 citations

Anatomical Plasticity and Sparing of Function After Spinal Cord Damage in Neonatal Cats

1982 • 154 citations

A quantitative autoradiographic and electrophysiological study of the reinnervation of the dentate gyrus by the contralateral entorhinal cortex following ipsilateral entorhinal lesions

1976 • 150 citations

Rapid transneuronal degeneration and death of cortical neurons following removal of the olfactory bulb in adult rats

1978 • 147 citations

Specific projections of retina transplanted to rat brain

1980 • 142 citations

Histochemical evidence of altered development of cholinergic fibers in the rat dentate gyrus following lesions: I. Time course after complete unilateral entorhinal lesion at various ages

1977 • 139 citations

Postlesion Axonal Growth Produces Permanent Functional Connections

1973 • 136 citations

Spinal cord transplants permit the growth of serotonergic axons across the site of neonatal spinal cord transection

1987 • 135 citations

Ultrastructural evidence for bouton proliferation in the partially deafferented dentate gyrus of the adult rat

1977 • 131 citations

Fine structural aspects of the synaptic organization of spinal trigeminal nucleus (pars interpolaris) of the cat

1971 • 127 citations

Compensatory synapse growth in aged animals after neuronal death

1979 • 126 citations

Rapid dendritic atrophy following deafferentation: An EM morphometric analysis

1977 • 124 citations

Some observations on transneuronal cell degeneration in the olfactory bulb of the rabbit.

1962 • 121 citations

Afferent influences on brain stem auditory nuclei of the chicken: Cessation of amino acid incorporation as an antecedent to age‐dependent transneuronal degeneration

1985 • 118 citations

Infant lesion effect: III. Anatomical correlates of sparing and recovery of function after spinal cord damage in newborn and adult cats

1983 • 114 citations

The effect of a conditioning lesion on the regeneration of motor axons

1978 • 114 citations

Transplantation of neural tissues in the brains of laboratory mammals: Technical details and comments

1979 • 113 citations

CENTRAL CHROMATOLYSIS AND THE AXON REACTION: A REAPPRAISAL

1976 • 111 citations

Terminal proliferation and synaptogenesis following partial deafferentation: The reinnervation of the inner molecular layer of the dentate gyrus following removal of its commissural afferents

1978 • 107 citations

Effect of a conditioning lesion on optic nerve regeneration in goldfish

1981 • 106 citations

Transplantation of embryonic occipital cortex to the brain of newborn rats

1980 • 104 citations

Ipsilateral corticospinal projections after large lesions of the cerebral hemisphere in neonatal rats

1975 • 104 citations

Transplantation of tectal tissue in rats. I. Organization of transplants and pattern of distribution of host afferents within them

1981 • 103 citations

Cryopreservation, Culture, and Transplantation of Human Fetal Mesencephalic Tissue into Monkeys

1988 • 100 citations

Axonal regeneration and functional plasticity in the central nervous system

1974 • 98 citations

Lesion‐induced synaptogenesis in the dentate gyrus of aged rats: II. Demonstration of an impaired degeneration clearing response

1982 • 96 citations

Synaptic reorganization of the red nucleus after chronic deafferentation from cerebellorubral fibers: an electron microscope study in the cat

1974 • 96 citations

Neural transplantation: A review of recent developments and potential applications to the aged brain

1985 • 91 citations

Axonal Sprouting of Ipsilateral Optic Tract Following Opposite Eye Removal

1973 • 90 citations

Neural transplants. Development and function

1987 • 90 citations

Retrograde transsynaptic cellular degeneration in mammillary and ventral tegmental nuclei following limbic decortication in rabbits of various ages

1969 • 87 citations

Reinnervation of Dentate Gyrus by Homologous Afferents Following Entorhinal Cortical Lesions in Adult Rats

1976 • 83 citations

History of central nervous system regeneration research

1975 • 81 citations

Terminal proliferation in the partially deafferented dentate gyrus: Time coureses for the appearance and removal of degeneration and the replacement of lost terminals

1979 • 80 citations

Infant lesions effect: I. Development of motor behavior following neonatal spinal cord damage in cats

1983 • 79 citations

Plasticity of the parallel Fiber-Purkinje cell synapse by spine takeover and new synapse formation in the adult rat

1982 • 79 citations

Time-dependent changes in commissural field potentials in the dentate gyrus following lesions of the entorhinal cortex in adult rats

1975 • 78 citations

Quantitative electron microscopic evidence for reinnervation in the adult rat interpeduncular nucleus after lesions of the fasciculus retroflexus

1979 • 77 citations

NEURAL TISSUE GRAFTS AND REPAIR OF THE INJURED SPINAL CORD

1985 • 75 citations

Lack of sprouting and its presence after lesions of the cat spinal cord

1982 • 73 citations

A quantitative study of synaptic reorganization in red nucleus neurons after lesion of the nucleus interpositus of the cat: an electron microscopic study involving intracellular injection of horseradish peroxidase

1982 • 73 citations

Fetal brain tissue transplants reduce visual deficits in adult rats with bilateral lesions of the occipital cortex

1985 • 73 citations

Transplantation of brain tissue in the brain of rat. II. Growth characteristics of neocortical transplants in hosts of different ages

1980 • 72 citations

Infant lesion effect: II. Sparing and recovery of function after spinal cord damage in newborn and adult cats

1983 • 71 citations

Assessing the Functional Significance of Lesion-Induced Neuronal Plasticity

1982 • 70 citations

Rapid changes in ultrastructure during deafferentation‐induced dendritic atrophy

1989 • 69 citations

Cortical transplants reveal CNS trophic interactions in situ

1984 • 67 citations

Sprouting in the avian brainstem auditory pathway: Dependence on dendritic integrity

1981 • 67 citations

Structural and functional evidence of plasticity in the central nervous system

1975 • 65 citations

Growth, differentiation, and viability of fetal rat cortical and spinal cord implants into adult rat spinal cord

1983 • 65 citations

Quantitative autoradiographic analysis of the time course of proliferation of contralateral entorhinal efferents in the dentate gyrus denervated by ipsilateral entorhinal lesions

1977 • 64 citations

Reinnervation of the dentate gyrus and recovery of alternation behavior following entorhinal cortex lesions.

1987 • 59 citations

Regeneration of Axons and Synaptic Complex Formation Rostral to the Site of Hemisection in the Spinal Cord of the Monkey

1973 • 59 citations

Transplantation of tectal tissue in rats

1982 • 57 citations

Effect of serial lesions on sprouting in the dentate gyrus: Onset and decline of the catalytic effect

1978 • 57 citations

Synapse formation after injury in the adult rat brain: preferential reinnervation of denervated fimbrial sites by axons of the contralateral fimbria

1980 • 56 citations

Reinnervation of the dentate gyrus and recovery of alternation behavior following entorhinal cortex lesions.

1987 • 54 citations

Changes in translation of synaptic excitation to dentate granule cell discharge accompanying long-term potentiation. I. Differences between normal and reinnervated dentate gyrus.

1981 • 54 citations

Lesions of the brachium of the superior colliculus in neonate hamsters: Correlation of anatomy with behavior

1981 • 53 citations

Chapter 25 Transplantation of fetal dopamine neurons in primate brain reverses MPTP induced parkinsonism

1987 • 51 citations

Rapid axon sprouting in the neonatal rat hippocampus

1978 • 49 citations

Fiber architecture of the dentate gyrus following ablation of the entorhinal cortex in rats of different ages: Evidence for two forms of axon sprouting in the immature brain

1981 • 49 citations

Persistence of post-synaptic membrane thickenings after degeneration of olfactory nerves

1969 • 49 citations

Fetal hypothalamic transplants in the third ventricle of the adult rat brain

1980 • 45 citations

Specificity of Synaptic Growth in Brain: Remodeling Induced by Kainic Acid Lesions

1979 • 44 citations

Functional effects of lesion-induced plasticity: Long term potentiation in normal and lesion-induced temporodentate connections

1979 • 43 citations

A study of terminal degeneration in the olfactory bulb of the rat

1972 • 43 citations

Chapter 6 The Regulation of Fiber Growth and Synaptogenesis In The Developing Hippocampus

1980 • 42 citations

Collateral projections of cells in the surviving entorhinal area which rein-nervate the dentate gyrus of the rat following unilateral entorhinal lesions

1978 • 41 citations

Terminal Arbors of Axons That Have Formed Abnormal Connections

1978 • 39 citations

Abnormal axonal growth in the dorsal lateral geniculate nucleus of the cat

1981 • 38 citations

Dopamine denervation does not alter in vivo ³H‐spiperone binding in rat striatum: Implications for external imaging of dopamine receptors in Parkinson's disease

1986 • 37 citations

Alteration in nicotinic and muscarinic responses of rabbit superior cervical ganglion cells after chronic preganglionic denervation

1976 • 37 citations

Principles of Cellular, Molecular, and Developmental Neuroscience

1989 • 35 citations

The organization of afferents to the lateral posterior nucleus in the golden hamster after different combinations of neonatal lesions

1980 • 34 citations

Histochemical evidence for a post‐lesion reorganization of cholinergic afferents in the hippocampal formation of the mature cat

1978 • 34 citations

Effect of neonatal deafferentation on synaptogenesis in the rat interpeduncular nucleus

1978 • 28 citations

Time course of reactive synaptogenesis in the subcortical somatosensory system

1987 • 28 citations

Habituation-like decrements in transmission along the normal and lesion-induced temporodentate pathways in the rat

1978 • 22 citations

A quantitative electron microscopic study of synaptic reorganization in the rat medial habenular nucleus after transection of the stria medullaris

1982 • 20 citations

Neurochemical Events Underlying Continued Function Despite Injury to Monoaminergic Systems

1986 • 18 citations

Responses in the hypoglossal nucleus to delayed regeneration of the transected hypoglossal nerve, a quantitative ultrastructural study

1977 • 17 citations

Quantitative demonstration of somatic synapi sprouting following dendritic deafferentation in neonatal rat interpeduncular nucleus

1979 • 14 citations

The effects of successive lesions on the time course of the sprouting response in the hippocampus of the rat

1982 • 13 citations

Deleted Work

1955 • 0 citations