Lipid peroxidation and changes in the ubiquinone content and the respiratory chain enzymes of submitochondrial particles

A SIMPLE METHOD FOR THE ISOLATION AND PURIFICATION OF TOTAL LIPIDES FROM ANIMAL TISSUES

1957 • 63,238 citations

DETERMINATION OF SERUM PROTEINS BY MEANS OF THE BIURET REACTION

1949 • 16,078 citations

[30] Microsomal lipid peroxidation

1978 • 12,818 citations

Methods of Biochemical Analysis

1956 • 4,535 citations

OXIDATION OF FREE AMINO ACIDS AND AMINO ACID RESIDUES IN PROTEINS BY RADIOLYSIS AND BY METAL-CATALYZED REACTIONS

1993 • 1,377 citations

Metal-catalyzed oxidation of proteins. Physiological consequences

1991 • 877 citations

The oxidative inactivation of mitochondrial electron transport chain components and ATPase.

1990 • 718 citations

Inhibition of Mitochondrial Electron Transport by Peroxynitrite

1994 • 697 citations

The protonmotive Q cycle. Energy transduction by coupling of proton translocation to electron transfer by the cytochrome bc1 complex.

1990 • 586 citations

Determination of the Activity of Succinate, NADH, Choline, and α‐Glycerophosphate Dehydrogenases

1974 • 318 citations

ADP/ATP carrier protein from beef heart mitochondria has high amounts of tightly bound cardiolipin, as revealed by phosphorus-31 nuclear magnetic resonance

1985 • 296 citations

Fenton chemistry. Amino acid oxidation.

1991 • 290 citations

Ubiquinol: an endogenous antioxidant in aerobic organisms

1993 • 270 citations

[47] Mammalian succinate dehydrogenase

1978 • 256 citations

Covalent modification reactions are marking steps in protein turnover

1990 • 211 citations

NADH- and NADPH-dependent lipid peroxidation in bovine heart submitochondrial particles. Dependence on the rate of electron flow in the respiratory chain and an antioxidant role of ubiquinol

1980 • 200 citations

[92a] Microsomal lipid peroxidation

1967 • 200 citations

Studies with Ubiquinone‐Depleted Submitochondrial Particles

1969 • 167 citations

Lipid peroxidation and phospholipase A2 activity in liposomes composed of unsaturated phospholipids: a structural basis for enzyme activation

1988 • 154 citations

[87] Energy-coupling in nonphosphorylating submitochondrial particles

1967 • 152 citations

Inhibition of lipid peroxidation by ubiquinol in submitochondrial particles in the absence of vitamin E

1991 • 125 citations

Mitochondria contain a proteolytic system which can recognize and degrade oxidatively-denatured proteins

1988 • 122 citations

Endogenous ubiquinol prevents protein modification accompanying lipid peroxidation in beef heart submitochondrial particles

1995 • 111 citations

The mode of action of lipid-soluble antioxidants in biological membranes: relationship between the effects of ubiquinol and vitamin E as inhibitors of lipid peroxidation in submitochondrial particles.

1992 • 109 citations

The essential functions of coenzyme Q

1993 • 105 citations

Oxidative Processes and Antioxidants

1995 • 100 citations

The Mode of Action of Lipid-Soluble Antioxidants in Biological Membranes. Relationship between the Effects of Ubiquinol and Vitamin E as Inhibitors of Lipid Peroxidation in Submitochondrial Particles

1992 • 94 citations

Studies with Ubiquinone‐Depleted Submitochondrial Particles

1970 • 86 citations

Alteration of inner-membrane components and damage to electron-transfer activities of bovine heart submitochondrial particles induced by NADPH-dependent lipid peroxidation

1982 • 85 citations

Studies on reduced and oxidized coenzyme Q (ubiquinones). II. The determination of oxidation-reduction levels of coenzyme Q in mitochondria, microsomes and plasma by high-performance liquid chromatography

1982 • 75 citations

[7] Preparation and properties of dihydroubiquinone: Cytochrome c oxidoreductase (complex III)

1978 • 74 citations

Cytochrome c oxidase and cardiolipin alterations in response to skeletal muscle ischaemia and reperfusion

1990 • 71 citations

Highlights in ubiquinone research

1990 • 63 citations

Evidence for a protective effect of endogenous ubiquinol against oxidative damage to mitochondrial protein and DNA during lipid peroxidation

1994 • 61 citations

The inactivation of mitochondrial F1 ATPase by H2O2 is mediated by iron ions not tightly bound in the protein

1991 • 57 citations

Coenzyme Q can control the efficiency of oxidative phosphorylation.

1990 • 52 citations

Protective effect of exogenous coenzyme Q against damage by adriamycin in perfused rat liver.

1994 • 39 citations

Effects of clofibrate, phthalates and probucol on ubiquinone levels

1994 • 39 citations

Oxygenation of biomembranes by mammalian lipoxygenases: The role of ubiquinone

1996 • 38 citations

Protective effect of endogenous coenzyme Q on both lipid peroxidation and respiratory chain inactivation induced by an adriamycin-iron complex

1987 • 35 citations

Succinate-dependent lipid peroxidation and its prevention by reduced ubiquinone in beef heart submitochondrial particles

1992 • 35 citations

Electrophoretic evidence for the impairment of complexes of the respiratory chain during iron/ascorbate induced peroxidation in isolated rat liver mitochondria

1995 • 34 citations

Evidence for two independent pathways of electron transfer in mitochondrial NADH:Q oxidoreductase. I. Pre-steady-state kinetics with NADPH

1986 • 34 citations

Effect of squalestatin 1 on the biosynthesis of the mevalonate pathway lipids

1994 • 32 citations

[12] Tightly coupled beef heart submitochondrial particles

1979 • 27 citations

Injury of mitochondrial respiration and membrane potential during iron/ascorbate-induced peroxidation

1988 • 26 citations

Initiation of lipid peroxidation in submitochondrial particles: Effect of respiratory inhibitors

1991 • 25 citations

Peroxidative damage to cardiac mitochondria: Identification and purification of modified adenine nucleotide translocase

1992 • 24 citations

Evidence for two independent pathways of electron transfer in mitochondrial NADH:Q oxidoreductase. II. Kinetics of reoxidation of the reduced enzyme

1986 • 23 citations

The polyunsaturated 20-carbon and 22-carbon fatty acids of euglena

1963 • 21 citations

Ubichinone und verwandte Substanzen, XIII.über Epoxy‐ubichinone

1969 • 12 citations

Ubichinone und verwandte Substanzen, XVI¹⁾ Photooxydation von Ubichinon‐7²⁾

1970 • 11 citations

A requirement for ubiquinone in ATPase activity and oxidative phosphorylation

1978 • 8 citations

Metabolic comparison between ubiquinone-7 and ubiquinone-9 in rats.

1971 • 8 citations

Fluorescent Substances and High Molecular Weight Protein Aggregates Formed in Rat Heart Mitochondria upon Doxorubicin-induced Lipid Peroxidation

1995 • 4 citations