Presynaptic α-adrenoceptors and the action of tricyclic antidepressant drugs in behavioural despair in rats

Depression: a new animal model sensitive to antidepressant treatments

1977 • 4,272 citations

THE CATECHOLAMINE HYPOTHESIS OF AFFECTIVE DISORDERS: A REVIEW OF SUPPORTING EVIDENCE

1965 • 3,421 citations

Behavioural despair in rats: A new model sensitive to antidepressant treatments

1978 • 3,035 citations

Effect of antidepressant drugs on the depletion of intraneuronal brain 5-hydroxytryptamine stores caused by 4-methyl-α-ethyl-meta-tyramine

1969 • 645 citations

Immobility induced by forced swimming in rats: Effects of agents which modify central catecholamine and serotonin activity

1979 • 576 citations

Inhibition of Uptake of Tritiated-noradrenaline in the Intact Rat Brain by Imipramine and Structurally Related Compounds

1964 • 506 citations

Preferential blockade of presynaptic α-adrenoceptors by yohimbine

1975 • 466 citations

Effects of some antidepressant drugs on the depletion of intraneuronal brain catecholamine stores caused by 4,α-dimethyl-meta-tyramine

1969 • 417 citations

Different alpha-adrenoreceptors in the central nervous system mediating biochemical and functional effects of clonidine and receptor blocking agents

1976 • 378 citations

Presynaptic receptor systems on the noradrenergic neurones of rat brain

1977 • 325 citations

Presynaptic Alpha-Receptor Subsensitivity After Long-Term Antidepressant Treatment

1978 • 320 citations

Comparison of the effects of clonidine on pre-and postsynaptic adrenoceptors in the rabbit pulmonary artery

1974 • 316 citations

Inhibition of adrenergic neurotransmission by clonidine: An action on prejunctional α-receptors

1973 • 225 citations

Norepinephrine Metabolites as Biochemical Criteria for Classifying Depressive Disorders and Predicting Responses to Treatment: Preliminary Findings

1973 • 204 citations

Biogenic amine hypothesis of affective disorders

1979 • 148 citations

Alpha-receptor-mediated modulation of transmitter release from central noradrenergic neurones

1973 • 105 citations

Interactions between clonidine and antidepressant drugs: A method for identifying antidepressant-like agents

1978 • 93 citations

The effect of acute and chronic desipramine and amitriptyline treatment on rat brain total 3-methoxy-4-hydroxyphenylglycol

1978 • 89 citations

Effects of tricyclic antidepressants on the uptake and metabolism of intracisternally administered norepinephrine-H3 in rat brain

1969 • 63 citations

Interaction of antidepressants with clonidine on rat brain total 3-methoxy-4-hydroxyphenylglycol

1979 • 53 citations

Alpha-receptor-mediated modulation of 3H-noradrenaline release from rat brain cortex synaptosomes

1978 • 47 citations

THE EFFECT OF AMITRIPTYLINE ON PRESYNAPTIC MECHANISMS IN NORADRENERGIC NERVES

1978 • 39 citations

The incorporation of [3H]-tyrosine into the enkephalins of striatal slices of guinea-pig brain [proceedings].

1978 • 31 citations

Enhancement of central norepinephrine and 5-hydroxytryptamine transmission by tricyclic antidepressants

1979 • 26 citations

Interaction between antidepressants and alpha-adrenergic receptor blocking agents.

1980 • 4 citations