Immunochemistry of Encephalitogenic Protein
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Abstract
References (385)
Thomas, Springfield, Illinois
1965 • 2,935 citations
Functional subclasses of T-lymphocytes bearing different Ly antigens. I. The generation of functionally distinct T-cell subclasses is a differentiative process independent of antigen.
1975 • 1,105 citations
Large Scale Preparation of Myelin Basic Protein from Central Nervous Tissue of Several Mammalian Species
1972 • 949 citations
Handbook of Clinical Neurology
1970 • 919 citations
The Structure and Function of Nervous Tissue
1972 • 905 citations
OBSERVATIONS ON ATTEMPTS TO PRODUCE ACUTE DISSEMINATED ENCEPHALOMYELITIS IN MONKEYS
1933 • 629 citations
TRANSFER OF ALLERGIC ENCEPHALOMYELITIS IN RATS BY MEANS OF LYMPH NODE CELLS
1960 • 540 citations
In Vitro Methods in Cell-Mediated Immunity
1971 • 507 citations
ENCEPHALOMYELITIS ACCOMPANIED BY MYELIN DESTRUCTION EXPERIMENTALLY PRODUCED IN MONKEYS
1935 • 433 citations
Suppression of experimental allergic encephalomyelitis by a synthetic polypeptide
1971 • 431 citations
The Structure and Function of Nervous Tissue
1969 • 429 citations
Antigenicity: Some Molecular Aspects
1969 • 418 citations
Experimental allergic encephalomyelitis
1969 • 406 citations
THE RAPID PRODUCTION OF ACUTE DISSEMINATED ENCEPHALOMYELITIS IN RHESUS MONKEYS BY INJECTION OF HETEROLOGOUS AND HOMOLOGOUS BRAIN TISSUE WITH ADJUVANTS
1947 • 398 citations
Basic A1 Protein of the Myelin Membrane
1971 • 352 citations
Maturation of human white matter myelin. Fractionation of the myelin membrane proteins
1968 • 343 citations
THE ENCEPHALOMYELITIC ACTIVITY OF MYELIN ISOLATED BY ULTRACENTRIFUGATION
1962 • 295 citations
Experimental Allergic Encephalomyelitis and Autoimmune Disease
1966 • 282 citations
Cellular hypersensitivity and immunity. Inhibition of macrophage migration and the lymphocyte mediators.
1972 • 260 citations
LYMPHOCYTE SENSITISATION: AN IN-VITRO TEST FOR CANCER ?
1970 • 247 citations
ALLERGIC ENCEPHALOMYELITIS IN MONKEYS IN RESPONSE TO INJECTION OF NORMAL MONKEY NERVOUS TISSUE
1947 • 226 citations
Primary demyelination as a nonspecific consequence of a cell-mediated immune reaction.
1975 • 224 citations
Amino acid sequence of the encephalitogenic basic protein from human myelin
1971 • 220 citations
The specific interaction of myelin basic protein with lipids at the air-water interface
1973 • 204 citations
Basis of microheterogeneity of myelin basic protein.
1976 • 200 citations
Isoallergic Encephalomyelitis and Radiculitis in Guinea Pigs After One Injection of Brain and Mycobacteria in Water-in-Oil Emulsion
1947 • 199 citations
Specific Enzymic Methylation of an Arginine in the Experimental Allergic Encephalomyelitis Protein from Human Myelin
1971 • 197 citations
Essential Chemical Requirements for Induction of Allergic Encephalomyelitis
1971 • 195 citations
Proteins of the Nervous System
1971 • 180 citations
Proteins of the nervous system
1973 • 180 citations
Experimental Allergic Encephalomyelitis: Synthesis of Disease-Inducing Site of the Basic Protein
1970 • 179 citations
Properties, Structure and Possible Neuroreceptor Role of the Encephalitogenic Protein of Human Brain
1971 • 175 citations
ENCEPHALITOGEN-INDUCED INHIBITION OF EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS: PREVENTION, SUPPRESSION AND THERAPY*
1965 • 175 citations
Chemical pathology of the nervous system
1962 • 174 citations
Allergic encephalomyelitis: the physico-chemical properties of the basic protein encephalitogen from bovine spinal cord
1969 • 173 citations
Specific Lymphocyte Sensitization in Cancer: Is There a Common Antigen in Human Malignant Neoplasia?
1971 • 169 citations
Topographical arrangement of membrane proteins in the intact myelin sheath. Lactoperoxidase incorproation of iodine into myelin surface proteins.
1975 • 164 citations
THE ISOLATION FROM BOVINE SPINAL CORD OF A HOMOGENEOUS PROTEIN WITH ENCEPHALITOGENIC ACTIVITY*
1962 • 164 citations
Amino acid sequence of the smaller basic protein from rat brain myelin
1974 • 159 citations
A RADIOIMMUNOASSAY FOR MYELIN BASIC PROTEIN AND ITS USE FOR QUANTITATIVE MEASUREMENTS
1975 • 158 citations
Recurrent Experimental Allergic Encephalomyelitis in the Lewis Rat
1974 • 155 citations
LINKAGE OF SUSCEPTIBILITY TO EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS TO THE MAJOR HISTOCOMPATIBILITY LOCUS IN THE RAT
1973 • 154 citations
Suppressor Cell Control of Unresponsiveness to Experimental Allergic Encephalomyelitis
1975 • 153 citations
Genetic Control of Susceptibility to Experimental Allergic Encephalomyelitis in Rats
1973 • 152 citations
CHEMICAL STUDIES ON AN ENCEPHALITOGENIC PROTEIN FROM GUINEA PIG BRAIN
1965 • 151 citations
Experimental Autoimmune Encephalomyelitis in Mice: Immunologic Response to Mouse Spinal Cord and Myelin Basic Proteins
1975 • 145 citations
In Vitro and in Vivo Phosphorylation of Myelin Basic Protein by Exogenous and Endogenous Adenosine 3′ : 5′-Monophosphate-dependent Protein Kinases in Brain
1974 • 145 citations
Chronic experimental allergic encephalomyelitis in inbred guinea pigs. An ultrastructural study.
1974 • 144 citations
THE ISOLATION AND CHARACTERIZATION OF AN ACID-SOLUBLE PROTEIN FROM MYELIN
1966 • 142 citations
THE PROTEIN COMPOSITION OF ISOLATED MYELIN1
1970 • 141 citations
Localization of Methylated Arginine in the A1 Protein from Myelin
1971 • 138 citations
Chemical Pathology of the Nervous System
1962 • 136 citations
Specific Cleavage of the A1 Protein from Myelin with Cathepsin D
1974 • 133 citations
Transfėr of Allergic Encephalomyelitis by Lymph Node Cells in Inbred Guinea Pigs
1961 • 128 citations
Suppression of experimental allergic encephalomyelitis in rhesus monkeys by a synthetic basic copolymer
1974 • 127 citations
Inhibition of Experimental Allergic Encephalomyelitis in Rats Severely Depleted of T Cells
1974 • 125 citations
THE FUNCTIONAL DISSECTION OF AN ANTIGEN MOLECULE: SPECIFICITY OF HUMORAL AND CELLULAR IMMUNE RESPONSES TO GLUCAGON
1971 • 123 citations
The proposed amino acid sequence of the P1 protein of rabbit sciatic nerve myelin
1972 • 123 citations
Suppression by several synthetic polypeptides of experimental allergic encephalomyelitis induced in guinea pigs and rabbits with bovine and human basic encephalitogen
1973 • 123 citations
AN ENCEPHALITOGENIC PROTEIN OF HUMAN ORIGIN; SOME CHEMICAL AND BIOLOGICAL PROPERTIES*
1965 • 122 citations
Experimental Allergic Encephalomyelitis in the Rat: Response to Encephalitogenic Proteins and Peptides
1973 • 122 citations
The passive transfer of experimental allergic encephalomyelitis and neuritis with living lymphoid cells
1962 • 121 citations
Experimental Allergic Encephalomyelitis in Inbred and Outbred Mice
1973 • 121 citations
THE RELATIONSHIP OF MYELIN PROTEINS TO EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS
1965 • 121 citations
Amino Acid Sequence of the Basic Protein of the Myelin Membrane
1970 • 120 citations
Chromatographic Fractionation of Myelin Basic Protein
1973 • 118 citations
Basic proteins from the acidic extract of bovine spinal cord
1966 • 115 citations
Phosphorylation of selected serine and threonine residues in myelin basic protein by endogenous and exogenous protein kinases
1974 • 115 citations
The protection of A1 myelin basic protein against the action of proteolytic enzymes after interaction of the protein with lipids at the air-water interface
1973 • 114 citations
Rapid Production of Acute Disseminated Encephalomyelitis in Rhesus Monkeys by Injection of Brain Tissue With Adjuvants
1946 • 112 citations
Specific interaction of central nervous system myelin basic protein with lipids. Specific regions of the protein sequence protected from the proteolytic action of trypsin
1973 • 108 citations
Multiple Sclerosis: Immunology, Virology, and Ultrastructure
1973 • 108 citations
CORRELATION OF EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS WITH DELAYED‐TYPE SKIN SENSITIVITY TO SPECIFIC HOMOLOGOUS ENCEPHALITOGEN*
1965 • 107 citations
Protein Antigens: The Molecular Bases of Antigenicity and Immunogenicity
1974 • 106 citations
Allergic encephalomyelitis: Preparation of the encephalitogenic basic protein from bovine brain
1970 • 105 citations
Resolution of insoluble proteins in rat brain subcellular fractions
1967 • 105 citations
Immunological Diseases.
1972 • 103 citations
In vivo and in vitro immunological cross‐reactions between basic encephalitogen and synthetic basic polypeptides capable of suppressing experimental allergic encephalomyelitis
1973 • 103 citations
Differences between the two myelin basic proteins of the rat central nervous system
1972 • 101 citations
The Folded Conformation of the Encephalitogenic Protein of the Human Brain
1974 • 99 citations
Basic encephalitogenic protein: A simplified purification on sulphoethyl‐sephadex
1970 • 99 citations
Myelin basic proteins of the rat central nervous system Purification, encephalitogenic properties, and amino acid compositions
1970 • 97 citations
Phosphorylation of Myelin Basic Protein
1974 • 97 citations
Biological Activity and Synthesis of an Encephalitogenic Determinant
1971 • 97 citations
Biology of Brain Dysfunction
1973 • 97 citations
Synthetic substrate for cyclic AMP-dependent protein kinase
1975 • 96 citations
Vesicular disruption of myelin in autoimmune demyelination
1975 • 95 citations
Isolation and partial characterization of the major proteins of rabbit sciatic nerve myelin
1975 • 94 citations
Phosphorylation of myelin basic protein by an adenosine 3′:5′-cyclic monophosphate-dependent protein kinase (Short Communication)
1973 • 90 citations
EXPERIMENTAL ALLERGIC ENCEPHALITIS
1972 • 89 citations
Genetic Control of Susceptibility to Experimental Allergic Encephalomyelitis and the Ag-B Locus of Rats
1975 • 89 citations
STOICHIOMETRIC RELATION OF PROTEIN COMPONENTS IN CEREBRAL MYELIN FROM DIFFERENT SPECIES1
1970 • 89 citations
Studies on the Species-Variability of Experimental Allergic Encephalomyelitis in Guinea Pigs and Rats
1974 • 87 citations
A conformation change induced in the basic encephalitogen by lipids
1971 • 86 citations
Antigen-induced inhibition of experimental allergic encephalomyelitis. III. Localization of an inhibitory site distinct from the major encephalitogenic determinant of myelin basic protein.
1975 • 85 citations
Degradation of encephalitogen by purified brain acid proteinase
1968 • 83 citations
Isolation and Properties of an Encephalitogenic Protein from Bovine, Rabbit, and Human Central Nervous System Tissue
1968 • 81 citations
Protective action of the encephalitogen and other basic proteins in experimental allergic encephalomyelitis
1968 • 81 citations
Glycosylation of the Al Protein from Myelin by a Polypeptide N-Acetylgalactosaminyltransferase
1971 • 80 citations
Allergic encephalomyelitis: A comparison of the encephalitogenic A1 protein from human and bovine brain
1970 • 78 citations
Experimental allergic encephalomyelitis. Isolation of basic proteins and polypeptides from central nervous tissue
1967 • 78 citations
Immunologic Properties of the Main Encephalitogenic Peptide from the Basic Protein of Human Myelin
1970 • 77 citations
Encephalitogenic Protein: Structure
1969 • 77 citations
Immuno-Electron Microscopic Localization of the Encephalitogenic Basic Protein in Myelin
1973 • 77 citations
Hyperacute, neutrophilic, and localized forms of experimental allergic encephalomyelitis: A review
1974 • 77 citations
Localization of Encephalitogenic Basic Protein in the Intraperiod Line of Lamellar Myelin
1970 • 77 citations
Encephalitogenic Fragment of Myelin Basic Protein
1971 • 76 citations
The immune response against myelin basic protein in two strains of rat with different genetic capacity to develop experimental allergic encephalomyelitis.
1975 • 76 citations
Antigen binding T and B lymphocytes. I. Differences in cellular specificity and influence of metabolic activity on interaction of antigen with T and B cells.
1974 • 75 citations
Isolation of Myelin Basic Proteins
1974 • 73 citations
PHYSICAL PROPERTIES OF THE BOVINE ENCEPHALITOGENIC PROTEIN; MOLECULAR WEIGHT AND CONFORMATION1
1970 • 73 citations
IN VITRO DEMONSTRATION OF CELLULAR SENSITIVITY IN ALLERGIC ENCEPHALOMYELITIS
1965 • 72 citations
Microheterogeneity of Guinea Pig Myelin Basic Protein
1969 • 72 citations
Antiinflammatory agents : chemistry and pharmacology
1974 • 72 citations
The Effects of the Injection of Normal Brain Emulsion into Rabbits, with Special Reference to the Aetiology of the Paralytic Accidents of Antirabic Treatment
1932 • 71 citations
Molecular conformation of bovine A1 basic protein, a coiling macromolecule in aqueous solution
1975 • 71 citations
Allergic encephalomyelitis. Isolation of an encephalitogenic peptide active in the monkey.
1975 • 69 citations
Allergic Encephalomyelitis
1971 • 68 citations
Metabolic Instability of Myelin Proteins
1975 • 68 citations
THE P2 PROTEIN OF BOVINE ROOT MYELIN: ISOLATION AND SOME CHEMICAL AND IMMUNOLOGICAL PROPERTIES1
1974 • 67 citations
Isolation and partial characterization of methylated arginines from the encephalitogenic basic protein of myelin
1971 • 67 citations
Molecular requirements involved in suppression of eae by synthetic basic copolymers of amino acids
1976 • 66 citations
CHEMICAL STUDIES ON EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS
1966 • 66 citations
Immunofluorescent Localization of Encephalitogenic Protein in Myelin
1964 • 66 citations
Myelin Basic Proteins of Mammalian and Submammalian Vertebrates: Encephalitogenic Activities in Guinea Pigs and Rats
1972 • 65 citations
Migration Enhancement Factor: A New Lymphokine
1974 • 65 citations
Allergic Encephalomyelitis
1971 • 64 citations
THE OCCURRENCE OF TWO MYELIN BASIC PROTEINS IN THE CENTRAL NERVOUS SYSTEM OF RODENTS IN THE SUBORDERS MYOMORPHA AND SCIUROMORPHA
1971 • 63 citations
Allergic encephalomyelitis: Isolation and characterization of encephalitogenic peptides from the basic protein of bovine spinal cord
1969 • 63 citations
Allergic encephalomyelitis: the structure of encephalitogenic determinant.
1968 • 62 citations
Autoimmune Encephalomyelitis: Activation of Thymus Lymphocytes against Syngeneic Brain Antigens in vitro
1974 • 60 citations
Isolation and Characterization of an Active Fragment from Enzymatic Degradation of Encephalitogenic Protein
1968 • 59 citations
Extraction of Rat Myelin Basic Protein Free of Other Basic Proteins of Whole Central Nervous System Tissue
1969 • 58 citations
Lipid and basic protein interaction in myelin
1974 • 58 citations
Allergic Encephalomyelitis in the Reputedly Resistant Brown Norway Strain of Rats
1975 • 57 citations
Turnover of Basic Protein of Rat Brain
1971 • 56 citations
Myelin Basic Protein: Location of Multiple Independent Antigenic Regions
1974 • 55 citations
Immune protection against experimental autoimmune encephalomyelitis: Optimal conditions and analysis of mechanism
1974 • 54 citations
Search for anti‐encephalitogen antibody in human demyelinative diseases
1968 • 54 citations
Suppression of the Immune Response: Reversal of the Disease State with Antigen in Allergic Encephalomyelitis
1972 • 53 citations
Immune Processes and Infectious Factors in Central Nervous System Disease
1969 • 53 citations
THE STRUCTURE AND IMMUNOLOGIC PROPERTIES OF BASIC PROTEINS OF MYELIN
1972 • 53 citations
Radioimmunoassay of myelin basic protein in sodium sulfate
1974 • 52 citations
Experimental allergic encephalomyelitis: Structural specificity of determinants for delayed hypersensitivity
1974 • 52 citations
Allergic encephalomyelitis: Cleavage of the C-tryptophyl bond in the encephalitogenic basic protein from bovine myelin
1969 • 52 citations
Immunohistological evidence of perivascular localization of basic protein in early development of experimental allergic encephalomyelitis
1974 • 51 citations
MACROMOLECULAR CONSTITUENTS OF MYELIN*
1965 • 51 citations
Localization of the Active Site through Chemical Modification of the Encephalitogenic Protein
1970 • 51 citations
Prevention of Allergic Encephalomyelitis by Prior Injection of Adjuvants
1958 • 50 citations
INDUCTION OF EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS IN RATS WITHOUT THE AID OF ADJUVANT*
1965 • 49 citations
Antigenic determinants of bovine myelin encephalitogenic protein recognized by rabbit antibody to myelin encephalitogenic protein
1975 • 49 citations
Antigen-Induced Inhibition of Experimental Allergic Encephalomyelitis
1975 • 49 citations
PROTEIN KINASES IN MYELIN OF RAT BRAIN: SOLUBILIZATION AND CHARACTERIZATION
1975 • 49 citations
ASSAY FOR INHIBITION OF MACROPHAGE MIGRATION
1971 • 48 citations
Isolation and Partial Characterization of Some Proteolytically and Chemically Derived Fragments of Bovine Encephalitogenic Protein
1971 • 48 citations
Detection of Antibodies to the Basic Protein of Human Myelin by Radioimmunoassay and Immunofluorescence
1971 • 47 citations
LOCALIZATION OF A BASIC PROTEIN IN THE MYELIN OF VARIOUS SPECIES WITH THE AID OF FLUORESCENCE AND ELECTRON MICROSCOPY
1965 • 47 citations
On the Statistical Evaluation of the Macrophage Migration Inhibition Assay
1973 • 47 citations
IMMUNE RESPONSE OF LYMPHOCYTES FROM PATIENTS WITH MULTIPLE SCLEROSIS TO PHYTOHEMAGGLUTININ, BASIC PROTEIN OF MYELIN AND MEASLES ANTIGENS
2009 • 46 citations
Induction of T-lymphocyte responses to a small molecular weight antigen. III. T-T cell interactions to determinants linked together: suppression vs. enhancement.
1975 • 46 citations
The structure of the terminal regions of the encephalitogenic basic protein from bovine myelin
1969 • 46 citations
Basic proteins from the acidic extract of bovine spinal cord
1966 • 46 citations
Allergic encephalomyelitis: Enzymatic degradation of the encephalitogenic basic protein from bovine spinal cord
1969 • 45 citations
Purification and Partial Characterization of a Basic Protein from Pig Brain
1967 • 45 citations
STUDIES ON THE ACID‐EXTRACTABLE PROTEINS OF BOVINE BRAIN WHITE MATTER*
1966 • 45 citations
The susceptibility of rat strains to experimental allergic encephalomyelitis.
1973 • 44 citations
Enzymatic degradation of myelin basic protein in central nervous system lesions of monkeys with experimental allergic encephalomyelitis.
1973 • 44 citations
METHYLASES OF MYELIN BASIC PROTEIN AND HISTONE IN RAT BRAIN
1975 • 44 citations
Immunopathological comparisons between experimental autoimmune encephalomyelitis and multiple sclerosis.
1973 • 44 citations
Pathogenesis and Etiology of Demyelinating Diseases
1970 • 43 citations
CHEMICAL AND IMMUNOCHEMICAL STUDIES WITH A DIALYZABLE ENCEPHALITOGENIC COMPOUND FROM BOVINE SPINAL CORD*
1965 • 43 citations
The neutralization of the mouse-adapted poliomyelitis virus by the sera of children.
1946 • 43 citations
ELECTROPHORETIC CHARACTERIZATION OF BASIC PROTEINS IN ACID EXTRACTS OF CENTRAL NERVOUS SYSTEM TISSUE
1971 • 43 citations
PARTIAL CHARACTERIZATION OF BASIC PROTEINS OF CHICKEN, TURTLE AND FROG CENTRAL NERVOUS SYSTEM MYELIN
1975 • 42 citations
ANTIBODY STUDIES IN RABBIT ENCEPHALOMYELITIS INDUCED BY A WATER-SOLUBLE PROTEIN FRACTION OF RABBIT CORD
1962 • 42 citations
Substitutes for the Mycobacteria in Freund's Adjuvants in the Production of Experimental “Allergic” Encephalomyelitis in the Guinea Pig
1964 • 42 citations
SOME BIOLOGICAL PROPERTIES OF A HIGHLY ACTIVE ENCEPHALITOGENIC FACTOR ISOLATED FROM HUMAN BRAIN
1963 • 42 citations
COMPARATIVE STUDIES OF GUINEA PIG AND BOVINE MYELIN BASIC PROTEINS. PARTIAL CHARACTERIZATION OF CHEMICALLY DERIVED FRAGMENTS AND THEIR ENCEPHALITOGENIC ACTIVITIES IN LEWIS RATS
1975 • 42 citations
Cellular transfer of experimental allergic encephalomyelitis: Altered disease pattern in irradiated recipient Lewis rats
1975 • 42 citations
Biological Activity of an Encephalitogenic Fragment in the Monkey
1972 • 41 citations
Immunologic Mechanisms in Experimental Encephalomyelitis in Nonhuman Primates
1973 • 41 citations
Binding of 125 I myelin basic protein by serum and cerebrospinal fluid.
1972 • 41 citations
Isolation of a Highly Purified Encephalitogenic Protein from Bovine Cord
1964 • 41 citations
Encephalitogenic basic protein from sciatic nerve
1969 • 41 citations
Allergic Encephalomyelitis in Monkeys Induced by a Peptide from the A1 Protein
1972 • 41 citations
ELECTROPHORETIC ANALYSIS OF THE HIGHLY BASIC PROTEINS OF THE RAT BRAIN FRACTION WHICH INDUCES EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS
1969 • 40 citations
Neuritogenic and Encephalitogenic Properties of the Peripheral Nerve Basic Proteins
1975 • 40 citations
Lymphocyte Sensitization to Basic Protein of Brain in Malignant Neoplasia: Experiments with Serotonin and Related Compounds
1971 • 40 citations
In vitro and in vivo phosphorylation of myelin basic protein by cerebral protein kinase
1974 • 39 citations
Radioimmunological Determination of Myelin Basic Protein (MBP) and MBP-Antibodies
1974 • 39 citations
The Location of Regions in Guinea Pig and Bovine Myelin Basic Proteins Which Induce Experimental Allergic Encephalomyelitis in Lewis Rats
1975 • 39 citations
Experimental allergic encephalomyelitis in congenic strains of mice
1974 • 39 citations
Large peptides of bovine and guinea pig myelin basic proteins produced by limited peptic hydrolysis
1975 • 39 citations
The location of regions in guinea pig and bovine myelin basic proteins which induce experimental allergic encephalomyelitis in Lewis rats.
1975 • 39 citations
Cell-Mediated Immunity—In Vitro Correlates.
1972 • 39 citations
On basic proteins in bovine peripheral nerve myelin
1975 • 38 citations
Protection against Experimental Allergic Encephalomyelitis
1972 • 38 citations
Role of T lymphocytes in the pathogenesis of experimental autoimmune encephalomyelitis
1973 • 38 citations
Antigen Binding T and B Lymphocytes
1974 • 38 citations
Purifications and properties of basic proteins in pig spinal cord and peripheral nerve
1970 • 38 citations
CRITICAL RELATIONSHIPS BETWEEN CONSTITUENTS OF THE ANTIGEN-ADJUVANT EMULSION AFFECTING EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS IN A COMPLETELY SUSCEPTIBLE MOUSE GENOTYPE
1962 • 37 citations
Inhibition of in vitro Cell Migration in Experimental Allergic Encephalomyelitis
1969 • 37 citations
Antigen-induced inhibition of experimental allergic encephalomyelitis. I. Inhibition in guinea pigs injected with non-encephalitogenic modified myelin basic protein.
1972 • 37 citations
ADJUVANT-ANTIGEN RELATIONSHIPS IN THE PRODUCTION OF EXPERIMENTAL "ALLERGIC" ENCEPHALOMYELITIS IN THE GUINEA PIG
1962 • 36 citations
The macrophage electrophoretic mobility (MEM) test for malignant disease. Further clinical investigations and studies on macrophage slowing factors.
1974 • 36 citations
Suppression and Reversal of Allergic Encephalomyelitis in Guinea Pigs with a Non-Encephalitogenic Analogue of the Tryptophan Region of the Myelin Basic Protein
1976 • 35 citations
Multiple Sclerosis: Progress in Research.
1972 • 34 citations
Acute and Chronic Autoimmune Encephalomyelitis: Age, Strain, and Sex Dependency The Importance of the Source of Antigen
1969 • 34 citations
Treatment of Experimental Allergic Encephalomyelitis with Encephalitogenic Basic Proteins
1972 • 34 citations
Dissociation of T Cell Helper Function and Delayed Hypersensitivity
1974 • 33 citations
Dialysable Peptide as the Causative Factor in Experimental ‘Allergic’ Encephalomyelitis
1962 • 33 citations
Localization of Antigenic Determinants on Bovine Encephalitogenic Protein
1972 • 33 citations
Competition between concanavalin A-induced stimulatory and inhibitory effects in the in vitro immune response to antigen.
1975 • 32 citations
Transformation of Rodent Lymphoid Cells by an Encephalitogen of Human Origin
1969 • 32 citations
The Antigenicity of Myelin Encephalitogenic Protein: Production of Antibodies to Encephalitogenic Protein with Deoxyribonucleic Acid—Encephalitogenic Protein Complexes
1975 • 32 citations
Immunological Disorders of the Nervous System
1973 • 32 citations
COMPARATIVE STUDIES OF HIGHLY BASIC PROTEINS OF OX BRAIN AND RAT BRAIN. MICROHETEROGENEITY OF BASIC ENCEPHALITOGENIC (MYELIN) PROTEIN
1969 • 31 citations
Cell-mediated immunity to Epstein–Barr virus and a blocking factor in patients with infectious mononucleosis
1974 • 31 citations
Comparison of experimental allergic encephalomyelitis induced with spinal cord, basic protein, and synthetic encephalitogenic peptide
1973 • 31 citations
Antigen-Binding Lymphocytes in Normal Man and Guinea Pig to Human Encephalitogenic Protein
1973 • 31 citations
Delayed Hypersensitivity to Myelin Basic Protein in the Passive Transfer of Experimental Allergic Encephalomyelitis
1968 • 31 citations
Studies of the metabolism of myelin basic proteins in various regions of the central nervous system of immature and adult rats
1971 • 31 citations
Interaction of Hallucinogenic Drugs with Encephalitogenic Protein of Myelin
1972 • 31 citations
Estimation of the molecular weight of flexible disordered proteins by exclusion chromatography
1969 • 31 citations
Radioimmunoassay with gel filtration for detecting antibody to basic proteins of myelin.
1968 • 30 citations
Prevention of experimental allergic encephalomyelitis by nonencephalitogenic basic peptides
1973 • 30 citations
Phytogeographical Classification of Mesozoic Floras and their Bearing on Continental Drift
1972 • 29 citations
Specificity and heterogeneity of helper T cells in the response to serum albumins in mice
1974 • 29 citations
Species specificity in response to tryptophan modified encephalitogen
1972 • 28 citations
Passive Transfer of Experimental Allergic Encephalomyelitis: Mechanisms of Suppression
1969 • 28 citations
RELEASE OF GLUTAMATE AND OTHER AMINO ACIDS FROM ARTHROPOD NERVE–MUSCLE PREPARATIONS
1976 • 28 citations
Allergic encephalomyelitis: immunologically specific inhibition of cellular passive transfer by encephalitogenic basic proteins.
1970 • 28 citations
Hydrolysis of myelin basic protein with brain acid proteinase
1974 • 28 citations
EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS: PROTECTION EXPERIMENTS WITH ENCEPHALITOGENIC FACTOR AND TUBERCLE FRACTIONS*
1965 • 27 citations
Multiple sclerosis : immunology, virology, and ultrastructure
1972 • 27 citations
Inhibition of Macrophage Migration in vitro by Brain and Encephalitogenic Factor in Allergic Encephalomyelitis
1968 • 27 citations
Gel Filtration of proteins at acid pH Application to molecular weight estimation of myelin basic proteins
1970 • 26 citations
MYELIN BASIC PROTEIN IN FROZEN AND UNFROZEN BOVINE BRAIN: A STUDY OF AUTOLYTIC CHANGES IN SITU1
1975 • 26 citations
Experimental Allergic Encephalomyelitis
1973 • 26 citations
Do Neurological Signs Occur in Experimental Allergic Encephalomyelitis in the Absence of Inflammatory Lesions of the Central Nervous System?
1975 • 26 citations
The immune response against an encephalitogenic fragment of guinea pig basic protein in the Lewis and Brown Norway strains or rat.
1975 • 26 citations
In vitro and in vivo immune responses to homologous myelin basic protein in experimental allergic encephalomyelitis
1974 • 25 citations
The Role of the Adrenal in Relapses of Experimental Allergic Encephalomyelitis
1975 • 25 citations
Multiple sclerosis: Progress in research
1972 • 25 citations
ISOLATION OF PURIFIED BASIC PROTEIN FROM HUMAN BRAIN
1973 • 25 citations
Encephalitogenic Peptides from Spinal Cord
1966 • 25 citations
The significance of circulating and cell-bound antibodies in experimental allergic encephalomyelitis.
1974 • 25 citations
Antigen-Induced Inhibition of Experimental Allergic Encephalomyelitis
1972 • 25 citations
Experimental allergic encephalomyelitis: Basic protein regions responsible for delayed hypersensitivity
1973 • 25 citations
Various Types of Acquired Resistance to Experimental ‘Allergic’ Encephalomyelitis
1959 • 25 citations
Communications. Encephalitogenic activity of peptides from the smaller basic protein of rat myelin.
1973 • 25 citations
N-terminal sequence of an encephalitogenic protein form human myelin
1969 • 25 citations
Relationships between Antibodies and Experimental Allergic Encephalomyelitis
1970 • 24 citations
Rat myelin basic proteins: relationship between size differences and microheterogeneity
1970 • 24 citations
Antigens and antigenicity
1969 • 24 citations
The extensive cross-reaction of several syngeneic rat-anti-BP antiserums with myelin basic proteins (BP) of other species
1976 • 23 citations
The Immune Response against an Encephalitogenic Fragment of Guinea Pig Basic Protein in the Lewis and Brown Norway Strains of Rat
1975 • 23 citations
PREVENTION OF EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS (EAE) BY VITAMIN C DEPRIVATION
1962 • 23 citations
Encephalitogenic Factor in Experimental ‘Allergic’ Encephalomyelitis
1963 • 23 citations
LYMPHOCYTES SENSITISED TO BASIC ENCEPHALITOGEN IN PATIENTS WITH MULTIPLE SCLEROSIS UNRESPONSIVE TO STEROID THERAPY
1974 • 23 citations
Experimental autoimmune encephalomyelitis. Digestion of basic protein of human myelin with cyanogen bromide and trypsin.
1970 • 23 citations
The Antibody Response to Myelin Basic Protein (BP) in Lewis Rats: The Effect of Time, Dosage of BP, and Dosage of Mycobacterium Butyricum
1974 • 23 citations
Allergic encephalomyelitis: Characterization of the determinants for delayed type hypersensitivity
1973 • 23 citations
Antigen-induced inhibition of experimental allergic encephalomyelitis. II. Studies in guinea pigs with the small rat myelin basic protein.
1973 • 22 citations
Experimental Allergic Encephalomyelitis (E.A.E.): Synthesis of the 7–11, 11–20, and 12–20 Peptides of Human Encephalitogenic Protein and Inhibition of Histological E.A.E. by the 12–20 Peptide
1972 • 22 citations
The Chicken A1 Protein
1974 • 22 citations
Properties of Antibodies Produced in Rabbits to Human Myelin and Myelin Basic Protein
1972 • 22 citations
Immune responses to myelin basic protein in mycobacterial-induced suppression of experimental allergic encephalomyelitis
1974 • 22 citations
Encephalitogenic Activity of Peptides from the Smaller Basic Protein of Rat Myelin
1973 • 22 citations
The Effect of Selective Modification of Tryptophan, Lysine and Arginine Residues of Basic Brain Protein on Encephalitogenic Activity
1970 • 21 citations
Lymphocyte Sensitivity to Encephalitogenic Factor in Guinea Pigs with Experimental Allergic Encephalomyelitis as Shown by <i>in vitro </i>Inhibition of Macrophage Migration
1968 • 21 citations
Lymphocytentransformation bei Multipler Sklerose
1974 • 21 citations
An In Vitro Assay for Encephalitogenic Components of Central Nervous Tissue
1968 • 21 citations
The ordered structure of the encephalitogenic protein from normal human myelin
1974 • 21 citations
Encephalitogenic activity in rabbits of the C‐terminal region of bovine basic myelin protein
1971 • 21 citations
Cell-Mediated Immunity in Experimental Allergic Encephalomyelitis: Cross Reactivity Between Myelin Basic Protein and Mycobacteria Antigens
1975 • 21 citations
Specific Binding of Peroxidase-Labeled Myelin Basic Protein in Allergic Encephalomyelitis
1971 • 21 citations
The Application of the Irradiated Hamster Test to the Study of Experimental Allergic Encephalomyelitis
1968 • 20 citations
Adoptive Transfer of Experimental Allergic Encephalomyelitis (EAE): Prevention of Successful Transfer by Treatment of Donors with Myelin Basic Protein
1975 • 20 citations
Relationships between Antibodies and Experimental Allergic Encephalomyelitis
1970 • 20 citations
Inhibition by serum of encephalitogenic activity of myelin basic protein: Nature of the serum factor responsible
1975 • 20 citations
EFFECT OF BASIC ENCEPHALITOGENIC PROTEIN AND SOME PEPTIDES DERIVED FROM IT ON THE MIGRATION IN AGAROSE GEL OF LEUKOCYTES FROM PATIENTS WITH MULTIPLE SCLEROSIS, OTHER NEUROLOGICAL DISEASES, OR CARCINOMA
2009 • 20 citations
Experimental allergic encephalomyelitis— properties of an iodinated encephalitogenic polypeptide
1967 • 20 citations
The localization of the basic protein and N-2 in diseased myelin
1975 • 20 citations
ANTIGEN UPTAKE BY SPECIFICALLY REACTIVE CELLS IN EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS*
1965 • 20 citations
Studies on brain antigens. VI. Prevention of experimental allergic encephalomyelitis by a water-soluble spinal cord protein, 1 -SCP.
1973 • 19 citations
Localization of antigenic determinants on bovine encephalitogenic protein. Studies in guinea pigs with macrophage migration inhibition
1972 • 19 citations
Isolated myelin quantitatively adsorbs antibody to basic protein
1974 • 19 citations
Studies on brain antigens. V. Purification and partial characterization of an anti-encephalitogenic spinal cord protein (SCP).
1972 • 19 citations
Studies of the catabolism of myelin basic proteins of the ratin situ andin vitro
1972 • 19 citations
Studies on Auto-Immune Encephalomyelitis in the Guinea Pig
1974 • 19 citations
Antigen-Induced Inhibition of Experimental Allergic Encephalomyelitis
1973 • 19 citations
The Antibody Responses to Myelin Basic Protein (BP) in Lewis Rats: The Effects of Bordetella Pertussis
1975 • 19 citations
Lymphocytes binding basic protein of myelin; cytophilic serum antibody and effect of adjuvant.
1973 • 19 citations
Skin-Fixing Antibody in Experimental Allergic Encephalomyelitis
1968 • 19 citations
Antigenic determinants in the N-terminal part of bovine encephalitogenic protein studied with the macrophage migration inhibition assay in guinea pigs. Evidence for an immunological reactivity of peptide 1–43 when tested on cells from animals injected with Freund's complete adjuvant
1973 • 18 citations
Experimental autoimmune demyelinating diseases: experimental allergic encephalomyelitis and experimental allergic neuritis.
1975 • 18 citations
Role of the thymus in tolerance. IX. Inhibition of experimental autoallergic encephalomyelitis by intrathymic injection of encephalitogen.
1970 • 18 citations
Comparison of Cross-Reactivities between Albumins of Various Species at the Level of Antibody and Helper T Cells—Studies in Mice
1974 • 18 citations
Fractionation of encephalitogenic polypeptides from bovine spinal cord by gel filtration in phenol--acetic acid--water.
1967 • 18 citations
Experimental Allergic Neuritis: Cells Binding Horseradish Peroxidase Conjugates of Myelin Basic Proteins
1974 • 18 citations
Experimental Allergic Encephalomyelitis in Resistant and Susceptible Guinea Pigs: In Vivo and in Vitro Correlates
1975 • 18 citations
Encephalitogenic activity in rabbits of the C‐terminal region of bovine basic myelin protein: Localization to two different regions
1972 • 17 citations
ELECTROPHORETIC STUDIES OF BASIC PROTEINS CAPABLE OF INDUCING EXPERIMENTAL ALLERGIC NEURITIS
1972 • 17 citations
Probable Identity of Tissue Specific Historie with Encephalitogenic Protein
1972 • 17 citations
Basic Protein of Myelin and Its Role in Experimental Allergic Encephalomyelitis and Multiple Sclerosis
1972 • 17 citations
Localization of antigenic determinants on bovine encephalitogenic protein further studies with the macrophage migration inhibition assay in guinea-pigs
1973 • 17 citations
Experimental allergic encephalitis: Study of cellular immunity to the encephalitogenic determinant
1975 • 16 citations
Non-encephalitogenic synthetic analogues of the determinant for allergic encephalomyelitis in guinea pigs
1975 • 16 citations
Relationships between Antibodies and Experimental Allergic Encephalomyelitis
1969 • 16 citations
Fractionation of Functional Lymphocytes Sensitized to Basic Encephalitogen on Derivatized Collagen and Gelatin Gels
1975 • 15 citations
The Encephautogenic Dose Response in Guinea Pigs of the Tryptophan Region of Myelin Basic Protein
1974 • 15 citations
Experimental Allergic Encephalomyelitis: Species Variability of the Encephalitogenic Determinant
1971 • 15 citations
Released myelin basic protein: The immunogenic factor?
1974 • 15 citations
Separation of T effector cells in humoral and cellular immunity
1974 • 15 citations
A Common Tumour Specific Antigen
1974 • 15 citations
Histones and Cancer Test
1973 • 15 citations
Non-encephalitogenic antigen-induced suppression and reversal of allergic encephalomyelitis
1975 • 14 citations
Protective Effect of Encephalitogenic Factor in Experimental Allergic Encephalomyelitis
1964 • 14 citations
The structure of the terminal regions of the encephalitogenic A1 protein
1969 • 14 citations
Correlation Between Strain Differences in Susceptibility to Experimental Allergic Encephalomyelitis and the Immune Response to Encephalitogenic Protein in Inbred Guinea Pigs
1973 • 14 citations
Immunological Disorders of the Nervous System
1972 • 14 citations
Induction and suppression of experimental allergic encephalomyelitis in the non-human primate
1974 • 14 citations
Immunologic Activity of Myelin Basic Protein in Strain 2 and Strain 13 Guinea Pigs
1975 • 14 citations
Studies on Brain Antigens
1972 • 13 citations
In Vitro Responses of Peripheral Blood Lymphocytes in Experimental Allergic Encephalomyelitis
1972 • 13 citations
Experimental Allergic Encephalomyelitis and cellular immunity in the Lewis rat
1974 • 13 citations
Immunological responses of guinea pigs to a synthetic autoantigen of brain
1974 • 13 citations
Mycobacterial Suppression of Delayed Hypersensitivity in Experimental Allergic Encephalomyelitis
1968 • 13 citations
Precipitating antibody in multiple sclerosis and experimental allergic encephalomyelitis: Specific binding of radio-iodinated encephalitogenic factor
1966 • 13 citations
A comparison of the encephalitogenic activities of human myelin basic protein and the synthetic peptide determinant comprising residues 114‐122
1975 • 13 citations
Role of the Thymus in Tolerance
1970 • 13 citations
Is there a cross-reactivity between different parts of the bovine encephalitogenic protein in the macrophage migration inhibition assay?
1973 • 13 citations
Identification of NG,N′G-dimethylarginine and NG,NG-dimethylarginine in the basic A1 protein from bovine myelin
1972 • 13 citations
Relation of measles virus to encephalitogenic factor with reference to the aetiopathogenesis of multiple sclerosis
1974 • 13 citations
Experimental allergic encephalomyelitis in cyclophosphamide-treated Lewis rats: Clinical remissions and relapses and effect of treatment on neuro-fibrin deposits
1974 • 12 citations
The Detection of Autoantibody-Forming Cells
1972 • 12 citations
Antigenic determinants on bovine encephalitogenic protein. Localization of regions that induce transformation of lymph node cells from immunized rabbits
1973 • 12 citations
The Central nervous system : some experimental models of neurological diseases
1968 • 12 citations
Basic A1 protein of myelin: relationship to experimental allergic encephalomyelitis.
1971 • 12 citations
Antigen-Induced Inhibition of Experimental Allergic Encephalomyelitis. IV. Studies of the C-Terminal end of the Myelin Basic Protein Molecule (1)
1975 • 11 citations
Experimental allergic encephalomyelitis: immunological properties of encephalitogenic polypeptides and proteins.
1967 • 11 citations
Relationships between Antibodies and Experimental Allergic Encephalomyelitis
1970 • 11 citations
Immunological cross-reactivity between basic proteins of myelin and cancer. I. Lymphocyte transformation studies in immunized guinea-pigs.
1975 • 11 citations
Humoral and Cell-Mediated Immune Responses of Lewis Rats to Syngeneic Basic Protein of Myelin
1974 • 11 citations
Allergic encephalomyelitis in monkeys induced with A-1 protein.
1972 • 11 citations
Studies on Brain Antigens
1973 • 11 citations
The Transformation and Proliferation of Lymphocytes in vitro1
2015 • 11 citations
Encephalitogenic protein: Aβ-pleated sheet conformation (102–120) yields a possible molecular form of a serotonin receptor
1972 • 10 citations
The proposed sequence of the encephalitogenic protein from chimpanzee brain
1975 • 10 citations
LEUKOCYTE MIGRATION IN AGAROSE, A STUDY ON MULTIPLE SCLEROSIS
1975 • 9 citations
Antigenic determinants on bovine encephalitogenic protein: studies in rabbits with derivatives of fragment 1-43 and the lymph node cell transformation test.
1973 • 9 citations
An explanation for the determination of “self” versus “non-self” proteins
1973 • 9 citations
Adjuvanticity of Synthetic Polynucleotides for Induction of Experimental Allergic Encephalomyelitis in Guinea Pigs
1974 • 9 citations
EFFECT OF ENCEPHALITOGENIC PROTEIN ON THE MIGRATION IN AGAROSE OF LEUCOCYTES FROM PATIENTS WITH MULTIPLE SCLEROSISCorrelations with Clinical Parameters, Localization of Antigenic Determinants, and Influence of Corticotrophin Treatment
1975 • 9 citations
Delayed-type Skin Sensitivity to Human Encephalitogen in Experimental Allergic Encephalomyelitis
1967 • 9 citations
Immunological aspects on demyelinating diseases.
1972 • 8 citations
Disease-inducing activity of different parts of bovine encephalitogenic protein in guinea-pigs.
1975 • 8 citations
The Antibody Response to Myelin Basic Protein in Lewis and Fischer Rats as Followed by a Sodium Sulfate Method of Radioimmunoassay
1974 • 8 citations
Studies on encephalitogenic fragments of myelin protein. IV. Synthesis of glycine analogs of tryptophan-containing fragment.
1974 • 8 citations
Inhibition of Macrophage Migration
2015 • 8 citations
Immunofluorescent Study of Circulating Antibody in Experimental Allergic Encephalomyelitis
1970 • 8 citations
Isolation and partial characterization of the myelin basic protein from fetal calf brains
1973 • 7 citations
Studies on Encephalitogenic Fragments of Myelin Protein. I. Synthesis of Tryptophan-containing Fragments
1973 • 7 citations
The detection of autoantibody-forming cells. I. An assay for plaque-forming cells to the basic protein of myelin in guinea-pigs.
1972 • 7 citations
Purification of Fully Active Human Encephalitogenic Basic Protein on Sulfoethyl-Sephadex
1972 • 7 citations
Clinical significance of immunopathological mechanisms in diseases of the nervous system
1971 • 7 citations
Immunologic Response to Altered Encephalitogenic Protein in Guinea Pigs
1969 • 6 citations
No Evidence for an Immunological Cross-Reaction between Encephalitogenic Myelin Basic Protein and Histones
1974 • 6 citations
Further studies on antigenic regions of bovine encephalitogenic protein with the lymph node cell transformation test in rabbits.
1974 • 6 citations
Localization of antigenic determinants on bovine encephalitogenic protein Studies in rabbits with the blood leukocyte transformation test
1972 • 6 citations
Localization of antigenic determinants on bovine encephalitogenic protein: disease-inducing activity of fragment 44-68 in rabbits.
1973 • 6 citations
The Detection of Autoantibody-Forming Cells
1972 • 6 citations
Studies on encephalitogenic fragments of myelin protein. III. Synthesis of H-Arg-Phe-Ser-Trp-Gly-Ala-Glu-Gly-Asn-Arg-OH as an analog of encephalitogenic decapeptide.
1974 • 5 citations
The Effects of Imidates on the Encephalitogenicity of Myelin Basic Protein
1975 • 5 citations
Immunological Comparison of Basic Encephalitogen and Histone F2A1
1975 • 5 citations
THE PRESENCE OF CYSTEINE IN FROG MYELIN BASIC PROTEIN
1975 • 4 citations
Effect of malnutrition on experimental allergic encephalomyelitis
1974 • 4 citations
Antibodies with a gliotoxic effect in sera from rabbits injected with peptide 1-43 of the bovine encephalitogenic protein.
1974 • 4 citations
THE CENTRAL NERVOUS SYSTEM. Some Experimental Models of Neurological Diseases
1969 • 4 citations
A simplified technique for the evaluation of antigen-binding cells
1973 • 3 citations
Temporal dissociation of experimental allergic encephalomyelitis transfer activity and gamma globulin staining of lymphoid cells from sensitized Lewis rats.
1970 • 3 citations
Immunologic Studies of Acetylated Encephalitogenic Myelin Basic Protein
1972 • 3 citations
Temporal Dissociation of Experimental Allergic Encephalomyelitis Transfer Activity and γ Globulin Staining of Lymphoid Cells from Sensitized Lewis Rats
1970 • 2 citations
Isolation and characterization of a basic encephalitogenic protein from the central nervous system of sheep
1975 • 2 citations