Protein kinase-catalyzed membrane phosphorylation and its possible relationship to the role of calcium in the adrenergic regulation of cardiac contraction

Calcium and muscle contraction

1968 • 1,745 citations

An Adenosine 3′,5′-Monophosphate-dependant Protein Kinase from Rabbit Skeletal Muscle

1968 • 1,423 citations

The Subunit Structure of Rabbit‐Skeletal‐Muscle Phosphorylase Kinase, and the Molecular Basis of Its Activation Reactions

1973 • 727 citations

Rate of Calcium Binding and Uptake in Normal Animal and Failing Human Cardiac Muscle: MEMBRANE VESICLES (RELAXING SYSTEM) AND MITOCHONDRIA

1969 • 521 citations

The regulation of the calcium conductance of cardiac muscle by adrenaline.

1977 • 475 citations

Phosphorylation of a 22,000-dalton component of the cardiac sarcoplasmic reticulum by adenosine 3':5'-monophosphate-dependent protein kinase.

1975 • 431 citations

Localization of beta adrenergic receptors, and effects of noradrenaline and cyclic nucleotides on action potentials, ionic currents and tension in mammalian cardiac muscle

1974 • 422 citations

Protein Kinases* *Support of the National Institutes of Arthritis and Metabolic Diseases, NIH, U. S. Public Health Service (AM 12842), the Muscular Dystrophy Association of America, and the American Heart Association is acknowledged.

1972 • 416 citations

The Regulation of Skeletal Muscle Phosphorylase Kinase by Ca2+

1971 • 416 citations

Cyclic nucleotides and nervous system function.

1977 • 411 citations

The effect of catecholamines on Na—K transport and membrane potential in rat soleus muscle

1977 • 403 citations

The Stimulation of Calcium Transport in Cardiac Sarcoplasmic Reticulum by Adenosine 3′:5′-Monophosphate-dependent Protein Kinase

1974 • 398 citations

Brief Reviews Exchange of Calcium Ions in the Mammalian Myocardium

1974 • 350 citations

Role of Cyclic Amp in Cell Function

1970 • 317 citations

A metabolic control mechanism for calcium ion influx that may protect the ventricular myocardial cell

1976 • 270 citations

Heart: Excitation-Contraction Coupling

1973 • 234 citations

Mechanism of Action of Epinephrine and Glucagon on the Canine Heart: EVIDENCE FOR INCREASE IN SARCOTUBULAR CALCIUM STORES MEDIATED BY CYCLIC 3',5'-AMP

1969 • 199 citations

Effects of adenosine 3':5'-monophosphate-dependent protein kinase on sarcoplasmic reticulum isolated from cardiac and slow and fast contracting skeletal muscles.

1976 • 189 citations

Cyclic Adenosine Monophosphate Modulation of Slow Calcium Influx Channels in Guinea Pig Hearts

1974 • 173 citations

Slow Ca2+ and Na+ responses induced by isoproterenol and methylxanthines in isolated perfused guinea pig hearts exposed to elevated K+

1975 • 172 citations

Calcium Requirements for Cardiac Myofibrillar Activation

1974 • 168 citations

The effect of substances releasing intracellular calcium ions on sodium‐dependent calcium efflux from guinea‐pig auricles.

1975 • 163 citations

Adenosine 3', 5'-Monophosphate-Dependent Membrane Phosphorylation

1974 • 156 citations

Regulation of adenosine 3:5-monophosphate-dependent protein kinase.

1975 • 155 citations

The rate of calcium uptake into sarcoplasmic reticulum of cardiac muscle and skeletal muscle. Effects of cyclic amp-dependent protein kinase and phosphorylase b kinase

1976 • 147 citations

Cyclic AMP stimulation of calcium efflux from kidney, liver, and heart mitochondria

1974 • 133 citations

Intact vesicles of canine cardiac sarcolemma: evidence from vectorial properties of Na+, K+-ATPase.

1976 • 133 citations

Die Restitution der Erregungsfortleitung und Kontraktionskraft des K+-gelähmten Frosch- und Säugetiermyokards durch Adrenalin

1961 • 119 citations

The complex carbohydrates of mammalian cell surfaces and their biological roles.

1975 • 108 citations

Parallel unmasking of latent adenylate cyclase and (Na+,K+)-ATPase activities in cardiac sarcolemmal vesicles. A new use of the channel-forming ionophore Alamethicin.

1977 • 97 citations

Calcium accumulation and cyclic AMP-stimulated phosphorylation in plasma membrane-enriched preparations of myocardium

1976 • 94 citations

Stimulation of calcium accumulation in cardiac sarcolemma by protein kinase

1976 • 86 citations

Reconstitution, Mechanism of Action and Control of Ion Pumps

1975 • 82 citations

Analysis of Calcium Binding and Release by Canine Cardiac Relaxing System (Sarcoplasmic Reticulum)

1973 • 73 citations

Physiological Significance of Ca Uptake by Mitochondria in the Heart in Comparison with that by Cardiac Sarcoplasmic Reticulum1

1976 • 72 citations

β-adrenergic effect on Na+-K+ transport in rat skeletal muscle

1977 • 68 citations

Cyclic AMP stimulation of membrane phosphorylation and Ca2+-activated, Mg2+-dependent ATPase in cardiac sarcoplasmic reticulum

1977 • 66 citations

Isolation of calcium pump system and purification of calcium ion-dependent ATPase from heart muscle

1976 • 63 citations

Isolation of sarcolemmal membranes from cardiac muscle

1976 • 60 citations

Mitochondria, Ca2+ transport and the regulation of heart contraction and metabolism

1975 • 59 citations

Correlation between protein kinase-mediated stimulation of calcium transport by cardiac sarcoplasmic reticulum and phosphorylation of a 22 000 dalton protein

1976 • 52 citations

A quench-flow kinetic investigation of calcium ion accumulation by isolated cardiac sarcoplasmic reticulum. Dependence of initial velocity on free calcium ion concentration and influence of preincubation with a protein kinase, MgATP, and cyclic AMP

1976 • 45 citations

Membrane phosphorylation and calcium transport in cardiac and skeletal muscle membranes

1976 • 40 citations

Contraction and Relaxation in the Myocardium

1976 • 32 citations

Phosphorylation of a low molecular weight polypeptide in beef heart Na+,K+-ATPase preparations

1976 • 28 citations

Calcium binding to rat heart plasma membranes: isolation and purification of a lipoprotein component with a high calcium binding capacity

1977 • 25 citations

Cyclic 3′,5′‐Nucleotides: mechanisms of action

1978 • 24 citations

Initial calcium binding rates of canine cardiac relaxing system (sarcoplasmic reticulum fragments) determined by stopped-flow spectrophotometry

1971 • 20 citations

Regulation of calcium transport by cyclic AMP. A proposed mechanism for the beta-adrenergic control of myocardial contractility.

1975 • 20 citations

A calcium-stimulated, ouabain-inhibited ATPase in a myocardial fraction enriched with sarcolemma

1973 • 19 citations

Adenosine 3′ : 5′-Cyclic Monophosphate Stimulation of Calcium Efflux from Mitochondria

1974 • 18 citations

The Biphasic Ca²⁺-Uptake by the Fragmented Sarcoplasmic Reticulum

1975 • 17 citations

Stimulation of cardiac sarcolemmal (Na+  K+)ATPase activity by phosphorylase kinase

1977 • 13 citations

The cardiac sarcoplasmic reticulum-glycogenolytic complex A possible effector site for cyclic

1977 • 13 citations

Phosphorylase kinase mediating the effects of cyclic AMP in muscle

1975 • 11 citations

Stimulation of calcium accumulation in cardiac sarcolemma by phosphorylase kinase

1977 • 9 citations

Role of cyclic nucleotides in the regulation of mitochondrial calcium uptake and efflux kinetics

1977 • 7 citations

Female cystourethritis

1973 • 1 citations