Myelin Pathology in the Twitcher Mouse^a

The Metabolic Basis of Inherited Disease

1990 • 4,327 citations

Globoid Cell Leucodystrophy (Krabbe's Disease): Deficiency of Galactocerebroside β-Galactosidase

1970 • 447 citations

Krabbe disease: a galactosylsphingosine (psychosine) lipidosis.

1980 • 310 citations

A NEW FAMILIAL, INFANTILE FORM OF DIFFUSE BRAIN-SCLEROSIS

1916 • 302 citations

Globoid cell leukodystrophy: Additional deficiency of psychosine galactosidase

1972 • 272 citations

The twitcher mouse: an enzymatically authentic model of human globoid cell leukodystrophy (Krabbe disease)

1980 • 251 citations

Neurological Mutations Affecting Myelination

1981 • 242 citations

HEREDITARY LEUCODYSTROPHY IN THE MOUSE: THE NEW MUTANT TWITCHER

1980 • 236 citations

Progressive Accumulation of Toxic Metabolite in a Genetic Leukodystrophy

1984 • 225 citations

Donor-Derived Cells in the Central Nervous System of Twitcher Mice After Bone Marrow Transplantation

1988 • 181 citations

Prolonged Survival and Remyelination After Hematopoietic Cell Transplantation in the Twitcher Mouse

1984 • 167 citations

Demyelination and remyelination in the rat central nervous system following ethidium bromide injection.

1979 • 120 citations

Vesicular disruption of myelin in autoimmune demyelination

1975 • 95 citations

Effect of bone marrow transplantation on enzyme levels and clinical course in the neurologically affected twitcher mouse.

1988 • 93 citations

Hematopoietic cell transplantation in murine globoid cell leukodystrophy (the twitcher mouse): effects on levels of galactosylceramidase, psychosine, and galactocerebrosides.

1987 • 83 citations

Progress in neuropathology

1984 • 82 citations

Accumulation of Galactosylsphingosine (Psychosine) in the Twitcher Mouse: Determination by HPLC

1987 • 72 citations

The twitcher mouse: Determination of genetic status by galactosylceramidase assays on clipped tail

1982 • 71 citations

The twitcher mouse: accumulation of galactosylsphingosine and pathology of the sciatic nerve

1988 • 62 citations

Infantile and fetal globoid cell leukodystrophy: Analysis of galactosylceramide and galactosylsphingosine

1988 • 61 citations

The twitcher mouse. Central nervous system pathology after bone marrow transplantation.

1988 • 49 citations

Ultrastructural study of experimental globoid cells.

1970 • 48 citations

The twitcher mouse: normal pattern of early myelination in the spinal cord

1982 • 47 citations

Tubules of Globoid Leukodystrophy: A Right-Handed Helix

1970 • 46 citations

Peripheral neuropathy in globoid cell leucodystrophy (Morbus Krabbe)

1968 • 46 citations

The twitcher mouse: degeneration of oligodendrocytes in vitro

1986 • 43 citations

Expression of glial fibrillary acidic protein in the CNS and PNS of murine globoid cell leukodystrophy, the twitcher.

1986 • 38 citations

The twitcher mouse: accumulation of galactosylsphingosine and pathology of the central nervous system

1989 • 38 citations

The twitcher mouse: An ultrastructural study on the oligodendroglia

1983 • 37 citations

Demyelination in the spinal cord of murine globoid cell leukodystrophy (the twitcher mouse)

1984 • 37 citations

ULTRASTRUCTURE OF GLOBOID LEUKODYSTROPHY (KRABBEʼS DISEASE) WITH REFERENCE TO THE ORIGIN OF GLOBOID CELLS

1970 • 35 citations

Studies on the Pathogenesis of Krabbe’s Leukodystrophy: Cellular Reaction of the Brain to Exogenous Galactosylsphingosine, Monogalactosyl Diglyceride, and Lactosylceramide

1976 • 35 citations

Pathology of the peripheral nerve in the twitcher mouse following bone marrow transplantation

1988 • 33 citations

Enzyme replacement in grafted nerve of twitcher mouse

1983 • 32 citations

Glycosylceramide Synthesis in the Developing Spinal Cord and Kidney of the Twitcher Mouse, an Enzymatically Authentic Model of Human Krabbe Disease

1982 • 31 citations

Ultrastructure of experimentally produced globoid cells in the rat

1970 • 27 citations

The twitcher mouse. An alteration of the unmyelinated fibers in the PNS.

1988 • 26 citations

LIPIDS OF DEVELOPING BRAIN OF TWITCHER MOUSE: AN AUTHENTIC MURINE MODEL OF HUMAN KRABBE DISEASE

1983 • 25 citations

Sub-plasmalemmal linear density: A common structure in globoid cells and mesenchymal cells

1977 • 23 citations

The twitcher mouse: Positive immunohistochemical staining of globoid cells with monoclonal antibody against Mac-1 antigen

1985 • 22 citations

Glycolipids of the Spinal Cord, Sciatic Nerve, and Systemic Organs of the Twitcher Mouse

1984 • 21 citations

Isolation and morphologic characterization in vitro of Schwann cells of the twitcher mouse.

1990 • 11 citations

Cytochemical markers for mononuclear phagocytes as demonstrated in reactive microglia and globoid cells

1980 • 11 citations

Globoid cell leukodystrophy: Specialized contact of globoid cell with astrocyte in the brain of twitcher mouse

1982 • 7 citations

Metabolism of Psychosine in SV40-Transformed Schwann Cell Lines

1988 • 4 citations