Phosphorylation of insulin-like growth factor I receptor by the insulin receptor tyrosine kinase in intact cultured skeletal muscle cells

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes

1985 • 2,257 citations

The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF 1

1985 • 1,590 citations

Identification of phosphotyrosine as a product of epidermal growth factor-activated protein kinase in A-431 cell membranes.

1980 • 1,184 citations

Insulin Stimulates the Phosphorylation of the 95,000-Dalton Subunit of Its Own Receptor

1982 • 1,138 citations

The Syndromes of Insulin Resistance and Acanthosis Nigricans

1976 • 1,086 citations

Retention of differentiation potentialities during prolonged cultivation of myogenic cells.

1968 • 975 citations

Growth factors: Mechanism of action and relation to oncogenes

1984 • 885 citations

Culture of Normal Human Leukocytes

1967 • 774 citations

The subunit structures of two distinct receptors for insulin-like growth factors I and II and their relationship to the insulin receptor.

1982 • 709 citations

Insulin stimulates tyrosine phosphorylation of the insulin receptor in a cell-free system

1982 • 680 citations

Stimulation of tyrosine-specific phosphorylation by platelet-derived growth factor

1982 • 675 citations

The Nature and Regulation of the Receptors for Insulin-Like Growth Factors

1985 • 639 citations

Monoclonal antibodies to receptors for insulin and somatomedin-C.

1983 • 423 citations

Somatomedin-C stimulates the phosphorylation of the beta-subunit of its own receptor.

1983 • 395 citations

Direct Demonstration of Separate Receptors for Growth and Metabolic Activities of Insulin and Multiplication-stimulating Activity (an Insulinlike Growth Factor) Using Antibodies to the Insulin Receptor

1980 • 346 citations

p185, a product of the neu proto-oncogene, is a receptorlike protein associated with tyrosine kinase activity.

1986 • 341 citations

Demonstration of two subtypes of insulin-like growth factor receptors by affinity cross-linking.

1981 • 332 citations

Stimulation of tyrosine-specific phosphorylation in vitro by insulin-like growth factor I

1983 • 254 citations

Interactions of Insulin-Like Growth Factors I and II and Multiplication-Stimulating Activity with Receptors and Serum Carrier Proteins

1980 • 254 citations

Kinetic properties and sites of autophosphorylation of the partially purified insulin receptor from hepatoma cells.

1984 • 208 citations

Distinct biologically active receptors for insulin, insulin-like growth factor I, and insulin-like growth factor II in cultured skeletal muscle cells.

1985 • 187 citations

Purification and Characterization of Multiplication‐Stimulating Activity

1980 • 171 citations

Insulin-like effect of vanadate on adipocyte glycogen synthase and on phosphorylation of 95,000 dalton subunit of insulin receptor

1983 • 162 citations

Differences in the sites of phosphorylation of the insulin receptor in vivo and in vitro.

1985 • 151 citations

Predominance of tyrosine phosphorylation of insulin receptors during the initial response of intact cells to insulin.

1985 • 146 citations

Purification of the catalytically active phosphorylated form of insulin receptor kinase by affinity chromatography with O-phosphotyrosyl-binding antibodies

1985 • 124 citations

Phosphorylation and dephosphorylation of the insulin receptor: evidence against an intrinsic phosphatase activity

1984 • 122 citations

Insulin-like growth factor-I (IGF-I) stimulates tyrosine kinase activity in purified receptors from a rat liver cell line

1984 • 89 citations

Antireceptor antibodies as probes of insulinlike growth factor receptor structure.

1983 • 85 citations

[48] Phosphorylation of the insulin receptor in cultured hepatoma cells and a solubilized system

1985 • 82 citations

The Development of Insulin Receptors and Responsiveness Is an Early Marker of Differentiation in the Muscle Cell Line L6*

1986 • 81 citations

Insulin-Like Growth Factor Receptors in Rat Placental Membranes*

1984 • 39 citations