Regulation of Mitochondrial Respiration by Oxygen and Nitric Oxide

Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide.

1987 • 5,027 citations

Nitric oxide as a secretory product of mammalian cells

1992 • 4,437 citations

NITRIC OXIDE: A Physiologic Messenger Molecule

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The Respiratory Chain and Oxidative Phosphorylation

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1967 • 1,785 citations

Reversible inhibition of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, by nitric oxide

1994 • 1,214 citations

Nanomolar concentrations of nitric oxide reversibly inhibit synaptosomal respiration by competing with oxygen at cytochrome oxidase

1994 • 1,026 citations

Production of superoxide radicals and hydrogen peroxide by NADH-ubiquinone reductase and ubiquinol-cytochrome c reductase from beef-heart mitochondria

1977 • 854 citations

Persistent inhibition of cell respiration by nitric oxide: Crucial role ofS-nitrosylation of mitochondrial complex I and protective action of glutathione

1998 • 825 citations

OXIDATIVE PHOSPHORYLATIONS: RÔLE OF INORGANIC PHOSPHATE AND ACCEPTOR SYSTEMS IN CONTROL OF METABOLIC RATES

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Nitric Oxide Inhibits Electron Transfer and Increases Superoxide Radical Production in Rat Heart Mitochondria and Submitochondrial Particles

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Role of ubiquinone in the mitochondrial generation of hydrogen peroxide

1976 • 656 citations

Contributions of mitochondria to animal physiology: from homeostatic sensor to calcium signalling and cell death

1999 • 610 citations

Nitric oxide synthase activity in mitochondria

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Production of Nitric Oxide by Mitochondria

1998 • 573 citations

The discovery of nitric oxide as the endogenous nitrovasodilator.

1988 • 486 citations

Transport of Oxygen in Muscle

1989 • 468 citations

The oxygen dependence of mitochondrial oxidative phosphorylation measured by a new optical method for measuring oxygen concentration.

1988 • 374 citations

Sites of inhibition of mitochondrial electron transport in macrophage-injured neoplastic cells.

1982 • 349 citations

Purification and Characterization of a Nitric-oxide Synthase from Rat Liver Mitochondria

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Control of mitochondrial and cellular respiration by oxygen

1995 • 303 citations

Purification of nitric oxide synthase from rat macrophages

1991 • 244 citations

Functional implications of nitric oxide produced by mitochondria in mitochondrial metabolism

1998 • 221 citations

Cellular energetics and the oxygen dependence of respiration in cardiac myocytes isolated from adult rat.

1990 • 207 citations

Nitric oxide regulates oxygen uptake and hydrogen peroxide release by the isolated beating rat heart

1998 • 192 citations

Oxygen-Dependent Regulation of Mitochondrial Energy Metabolism by Nitric Oxide

1995 • 156 citations

The reaction of nitric oxide with ubiquinol: kinetic properties and biological significance

1999 • 155 citations

Mitochondrial functions under hypoxic conditions: The steady states of cytochrome c reduction and of energy metabolism

1974 • 149 citations

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1999 • 139 citations

Kinetics of the inhibition of mitochondrial respiration by NO

1997 • 125 citations

Liver and heart mitochondria in rats submitted to chronic hypobaric hypoxia

1988 • 93 citations

Intracellular PO2 in individual cardiac myocytes in dogs, cats, rabbits, ferrets, and rats

1991 • 83 citations

Intracellular PO2 in long axis of individual fibers in working dog gracilis muscle

1988 • 82 citations

Oxygen dependence of mitochondrial function measured by high-resolution respirometry in long-term hypoxic rats

1997 • 74 citations

Cytochrome c Oxidase Catalysis of the Reduction of Nitric Oxide to Nitrous Oxide

1995 • 72 citations

Regulation of mitochondrial energy generation in health and disease

1995 • 58 citations

Oxygen dependence and subcellular partitioning of hepatic menadione-mediated oxygen uptake

1985 • 57 citations

Oxygen sensitivity of mitochondrial metabolic state in isolated skeletal and cardiac myocytes

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Coordinated Multisite Regulation of Cellular Energy Metabolism

1992 • 21 citations

Response of cyt a,a3 in the in situ canine heart to transient ischemic episodes

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Regulation of Oxygen Metabolism by Nitric Oxide

2000 • 19 citations

[1] Interaction of cytochrome-c oxidase with nitric oxide

1996 • 8 citations