Recombinant fusion protein identified by lepromatous sera mimics native Mycobacterium leprae in T-cell responses across the leprosy spectrum.
Data up to Jan 2025
Total Citations Per Year
Abstract
References (25)
DNA sequencing with chain-terminating inhibitors
1977 • 69,181 citations
A simple method for displaying the hydropathic character of a protein
1982 • 22,471 citations
Classification of leprosy according to immunity. A five-group system.
1966 • 2,459 citations
Stress proteins are immune targets in leprosy and tuberculosis.
1988 • 446 citations
A malaria T-cell epitope recognized in association with most mouse and human MHC class II molecules
1988 • 384 citations
PROTEIN SECRETION IN ESCHERICHIA COLI
1985 • 334 citations
Genes for the major protein antigens of the leprosy parasite Mycobacterium leprae
1985 • 316 citations
A simple new method for using antigens separated by polyacrylamide gel electrophoresis to stimulate lymphocytes in vitro after converting bands cut from Western blots into antigen-bearing particles
1987 • 231 citations
Human T-cell clones recognize a major M. leprae protein antigen expressed in E. coli
1986 • 164 citations
Antigenic relatedness of a strongly immunogenic 65 kDA mycobacterial protein antigen with a similarly sized ubiquitous bacterial common antigen
1988 • 152 citations
Immunological Aspects of Leprosy � Present Status
2015 • 138 citations
Mycobacterium leprae-specific protein antigens defined by cloned human helper T cells
1986 • 117 citations
Homology of the 70-kilodalton antigens from Mycobacterium leprae and Mycobacterium bovis with the Mycobacterium tuberculosis 71-kilodalton antigen and with the conserved heat shock protein 70 of eucaryotes
1989 • 114 citations
Use of recombinant antigens expressed in Escherichia coli K-12 to map B-cell and T-cell epitopes on the immunodominant 65-kilodalton protein of Mycobacterium bovis BCG
1988 • 101 citations
Antigenic proteins of Mycobacterium leprae. Complete sequence of the gene for the 18-kDa protein.
1988 • 71 citations
Fluorescent leprosy antibody absorption (FLA-ABS) test for detecting subclinical infection with Mycobacterium leprae.
1980 • 58 citations
T-cell recognition of the 18-kilodalton antigen of Mycobacterium leprae
1989 • 56 citations
A major immunogenic 36,000-molecular-weight antigen from Mycobacterium leprae contains an immunoreactive region of proline-rich repeats
1990 • 54 citations
A 28-kDa protein from Mycobacterium leprae is a target of the human antibody response in lepromatous leprosy.
1988 • 53 citations
Monoclonal antibodies to a 28,000 mol. wt protein antigen of Mycobacterium leprae.
1985 • 44 citations
Identification and characterization of antigenic determinants of Mycobacterium leprae that react with antibodies in sera of leprosy patients
1990 • 39 citations
Studies of mycobacterial antigens, with special reference to Mycobacterium leprae
1976 • 35 citations
Analysis of human antibody epitopes on the 65-kilodalton protein of Mycobacterium leprae by using synthetic peptides
1989 • 24 citations
A comparative evaluation of serological assays for lepromatous leprosy
1988 • 20 citations
Nucleotide and deduced amino acid sequence ofMycobacterium lepraemanganese superoxide dismutase
1989 • 16 citations