Effects of the selective thromboxane synthetase inhibitor dazoxiben on variations in cyclic blood flow in stenosed canine coronary arteries.

An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation

1976 • 3,613 citations

Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides.

1975 • 3,075 citations

Prevalence of Total Coronary Occlusion during the Early Hours of Transmural Myocardial Infarction

1980 • 2,722 citations

Blood flow measurements with radionuclide-labeled particles

1977 • 2,072 citations

Protective Effects of Aspirin against Acute Myocardial Infarction and Death in Men with Unstable Angina

1983 • 1,740 citations

Pharmacology and endogenous roles of prostaglandin endoperoxides, thromboxane A2, and prostacyclin.

1978 • 1,559 citations

Arachidonic Acid Metabolites and the Interactions between Platelets and Blood-Vessel Walls

1979 • 1,158 citations

Release of Prostaglandins and Thromboxane into the Coronary Circulation in Patients with Ischemic Heart Disease

1981 • 597 citations

Thromboxane A₂in Vasotonic Angina Pectoris

1981 • 226 citations

Platelet and Blood Vessel Arachidonate Metabolism and Interactions

1979 • 181 citations

ADMINISTRATION TO MAN OF UK-37,248-01, A SELECTIVE INHIBITOR OF THROMBOXANE SYNTHETASE

1981 • 168 citations

Stimulation of prostaglandin formation by vasoactive mediators in cultured human endothelial cells

1982 • 139 citations

Synchronized pulsed Doppler blood flow and ultrasonic dimension measurement in conscious dogs

1978 • 136 citations

Prevention of blockage of partially obstructed coronary arteries with prostacyclin correlates with inhibition of platelet aggregation

1979 • 135 citations

Endogenous prostacyclin contributes to the efficacy of a thromboxane synthetase inhibitor for preventing coronary artery thrombosis.

1981 • 120 citations

Clinicopathologic correlates of acute ischemic heart disease syndromes

1981 • 114 citations

Prostaglandins and ischemic heart disease

1981 • 98 citations

Urinary excretion of prostaglandin E2, prostaglandin F2 alpha, and thromboxane B2 in normotensive and hypertensive subjects on varying sodium intakes.

1982 • 51 citations

The beneficial effects of oral ibuprofen on coronary artery thrombosis and myocardial ischemia in the conscious dog.

1980 • 45 citations

Comparison of coronary arteriograms with direct measurements of stenosed coronary arteries in dogs

1978 • 43 citations

Effect of the thromboxane synthetase inhibitor UK-37,248 (dazoxiben) upon platelet aggregation, coronary artery thrombosis and vascular reactivity.

1983 • 33 citations

Effects of prostaglandins and thromboxane A2 on the coronary circulation of adult dogs and puppies

1980 • 25 citations

Thromboxane A2/prostaglandin H2 directly stimulates platelet shape change independent of secreted ADP.

1982 • 16 citations

Thromboxane synthetase inhibitors differentially antagonize thromboxane receptors in vascular smooth muscle

1981 • 12 citations