Pulmonary Vascular Involvement in COPD

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

1980 • 12,033 citations

Bosentan Therapy for Pulmonary Arterial Hypertension

2002 • 2,715 citations

Multi-Organ, Multi-Lineage Engraftment by a Single Bone Marrow-Derived Stem Cell

2001 • 2,653 citations

A Comparison of Continuous Intravenous Epoprostenol (Prostacyclin) with Conventional Therapy for Primary Pulmonary Hypertension

1996 • 2,590 citations

Expression of Endothelin-1 in the Lungs of Patients with Pulmonary Hypertension

1993 • 1,829 citations

Regulation of differentiation of vascular smooth muscle cells

1995 • 1,681 citations

Treatment of Pulmonary Arterial Hypertension

2004 • 1,673 citations

Reduced Expression of Endothelial Nitric Oxide Synthase in the Lungs of Patients with Pulmonary Hypertension

1995 • 1,366 citations

Bone marrow-derived cells as progenitors of lung alveolar epithelium

2001 • 555 citations

Impairment of Endothelium-Dependent Pulmonary-Artery Relaxation in Chronic Obstructive Lung Disease

1991 • 538 citations

Nitric oxide regulates basal systemic and pulmonary vascular resistance in healthy humans.

1994 • 518 citations

CD8 + ve Cells in the Lungs of Smokers with Chronic Obstructive Pulmonary Disease

1999 • 491 citations

Rescue of Monocrotaline-Induced Pulmonary Arterial Hypertension Using Bone Marrow–Derived Endothelial-Like Progenitor Cells

2005 • 458 citations

Long-Term Oxygen Therapy Can Reverse the Progression of Pulmonary Hypertension in Patients with Chronic Obstructive Pulmonary Disease

1985 • 448 citations

Pulmonary hypertension in chronic obstructive pulmonary disease

2003 • 437 citations

Characterization of pulmonary vascular remodelling in smokers and patients with mild COPD

2002 • 420 citations

Effect of Cigarette Smoke Extract on Nitric Oxide Synthase in Pulmonary Artery Endothelial Cells

1998 • 324 citations

Endothelial dysfunction in pulmonary arteries of patients with mild COPD

1998 • 323 citations

Inflammatory Reaction in Pulmonary Muscular Arteries of Patients with Mild Chronic Obstructive Pulmonary Disease

1999 • 306 citations

Worsening of pulmonary gas exchange with nitric oxide inhalation in chronic obstructive pulmonary disease

1996 • 269 citations

Pulmonary vascular abnormalities and ventilation-perfusion relationships in mild chronic obstructive pulmonary disease.

1994 • 257 citations

Pulmonary vascular structure and function in chronic obstructive pulmonary disease.

1988 • 214 citations

Reduced Expression of Endothelial Nitric Oxide Synthase in Pulmonary Arteries of Smokers

2001 • 207 citations

Enhanced Expression of Vascular Endothelial Growth Factor in Pulmonary Arteries of Smokers and Patients with Moderate Chronic Obstructive Pulmonary Disease

2003 • 193 citations

Differentiation of Smooth Muscle Cells in Human Blood Vessels as Defined by Smoothelin, a Novel Marker for the Contractile Phenotype

1997 • 173 citations

A Pathophysiological Study of 10 Cases of Hypoxic Cor Pulmonale

1988 • 154 citations

Analysis of the structure of the muscular pulmonary arteries in patients with pulmonary hypertension and COPD: National Institutes of Health Nocturnal Oxygen Therapy Trial

1992 • 143 citations

Prostacyclin Prevents Pulmonary Endothelial Cell Apoptosis Induced by Cigarette Smoke

2007 • 139 citations

Early Effects of Oxygen Administration and Prognosis in Chronic Obstuctive Pulmonary Disease and Cor Pulmonale^1–3

1983 • 133 citations

Transplantation of Endothelial Progenitor Cells into the Lung to Alleviate Pulmonary Hypertension in Dogs

2004 • 131 citations

Circulating Vascular Progenitor Cells Contribute to Vascular Repair, Remodeling, and Lesion Formation

2003 • 125 citations

Lung disease in long-term cigarette smokers with and without chronic air-flow obstruction.

1984 • 115 citations

Identification of Vascular Progenitor Cells in Pulmonary Arteries of Patients with Chronic Obstructive Pulmonary Disease

2005 • 111 citations

Vimentin-containing smooth muscle cells in aortic intimal thickening after endothelial injury.

1982 • 106 citations

Effect of inhibitors of nitric oxide release and action on vascular tone in isolated lungs of pig, sheep, dog and man.

1994 • 98 citations

Effect of Long-Term Cigarette Smoke Exposure on Pulmonary Vascular Structure and Function in the Guinea Pig

1991 • 96 citations

Effects of bone marrow-derived cells on monocrotaline- and hypoxia-induced pulmonary hypertension in mice

2007 • 89 citations

Pilot study of losartan for pulmonary hypertension in chronic obstructive pulmonary disease

2005 • 88 citations

Long-term treatment of chronic obstructive lung disease by Nifedipine: an 18-month haemodynamic study

1988 • 60 citations

Cigarette Smoke Induces Rapid Changes in Gene Expression in Pulmonary Arteries

2002 • 53 citations

Endothelium-dependent and -independent responses to severe hypoxia in rat pulmonary artery

1993 • 49 citations

Guinea pig pulmonary hypertension caused by cigarette smoke cannot be explained by capillary bed destruction

1997 • 47 citations

Emphysema: An Autoimmune Vascular Disease?

2005 • 44 citations

Response to hypoxia of pulmonary arteries in chronic obstructive pulmonary disease: anin vitrostudy

2002 • 40 citations

Plasticity of CD133+ cells: Role in pulmonary vascular remodeling

2007 • 27 citations