Characterization of the mode of binding of substrates to the active site of Tetrahymena self-splicing RNA using 5-fluorouracil-substituted mini-exons

Improved Estimation of Secondary Structure in Ribonucleic Acids

1973 • 2,302 citations

Self-splicing RNA: Autoexcision and autocyclization of the ribosomal RNA intervening sequence of tetrahymena

1982 • 2,241 citations

Oligoribonucleotide synthesis using T7 RNA polymerase and synthetic DNA templates

1987 • 2,098 citations

Improved free-energy parameters for predictions of RNA duplex stability.

1986 • 1,472 citations

The Chemistry of Self-Splicing RNA and RNA Enzymes

1987 • 523 citations

The Intervening Sequence RNA of Tetrahymena Is an Enzyme

1986 • 498 citations

Phy M: an RNase activity specific for U and A residues useful in RNA sequence analysis

1980 • 325 citations

Specific interaction between the self-splicing RNA of Tetrahymena and its guanosine substrate: implications for biological catalysis by RNA

1984 • 263 citations

RNA catalysis and the origins of life

1986 • 247 citations

One binding site determines sequence specificity of Tetrahymena pre-rRNA self-splicing, trans-splicing, and RNA enzyme activity

1986 • 211 citations

A Specific Amino Acid Binding Site Composed of RNA

1988 • 203 citations

Splice-site selection by a self-splicing RNA of Tetrahymena

1986 • 134 citations

Kinetic analysis of T7 RNA polymerase-promoter interactions with small synthetic promoters

1987 • 134 citations

Complementary oligonucleotide binding to transfer RNA

1972 • 128 citations

Intermolecular exon ligation of the rRNA precursor of tetrahymena: Oligonucleotides can function as 5′ exons

1985 • 114 citations

Polynucleotide analogues

1966 • 103 citations

Three-dimensional model of the active site of the self-splicing rRNA precursor of Tetrahymena.

1987 • 99 citations

Role of conserved sequence elements 9L and 2 in self-splicing of the Tetrahymena ribosomal RNA precursor

1986 • 81 citations

Equilibrium between a wobble and ionized base pair formed between fluorouracil and guanine in DNA as studied by proton and fluorine NMR.

1988 • 74 citations

Sites of circularization of theTetrahymenarRNA IVS are determined by sequence and influenced by position and secondary structure

1985 • 68 citations

Selection of circularization sites in a group I IVS RNA requires multiple alignments of an internal template-like sequence

1987 • 60 citations

Kinetics for reaction of a circularized intervening sequence with CU, UCU, CUCU, and CUCUCU: mechanistic implications from the dependence on temperature and on oligomer and magnesium concentrations

1988 • 56 citations

Chemical consequences of the incorporation of 5-fluorouracil into DNA as studied by NMR

1987 • 50 citations

Coupling of Tetrahymena Ribosomal RNA Splicing to β-Galactosidase Expression in Escherichia coli

1985 • 50 citations

5′ exon requirement for self-splicing of the Tetrahymena thermophila pre-ribosomal RNA and identification of a cryptic 5′ splice site in the 3′ exon

1987 • 45 citations

Nucleosides. XLIV. Long-range proton-fluorine spin-spin coupling in 5-fluoropyrimidine nucleosides

1968 • 38 citations

Mechanism of recognition of the 5′ splice site in self-splicing group I introns

1986 • 36 citations

The cloning and overproduction of Escherichia coli uracil-DNA glycosylase

1984 • 26 citations

RNA Structure from A to Z

1987 • 25 citations

Partial assignment of resonances in the fluorine-19 nuclear magnetic resonance spectra of 5-fluorouracil-substituted transfer RNAs

1988 • 12 citations