Possible neuroprotective role of clusterin in Alzheimer's disease: a quantitative immunocytochemical study

“Mini-mental state”

1975 • 82,784 citations

The Consortium to Establish a Registry for Alzheimer's Disease (CERAD)

1991 • 4,669 citations

Oxidative Stress, Glutamate, and Neurodegenerative Disorders

1993 • 3,746 citations

The unbiased estimation of number and sizes of arbitrary particles using the disector

1984 • 2,539 citations

Profound Loss of Layer II Entorhinal Cortex Neurons Occurs in Very Mild Alzheimer’s Disease

1996 • 1,734 citations

Oxidative Stress in Neurodegenerative Diseases

1996 • 1,336 citations

Differences in the pattern of hippocampal neuronal loss in normal ageing and Alzheimer's disease

1994 • 1,213 citations

Skeletal and CNS Defects in Presenilin-1-Deficient Mice

1997 • 953 citations

Regionally specific loss of neurons in the aging human hippocampus

1993 • 612 citations

Evidence of neuronal oxidative damage in Alzheimer's disease.

1996 • 602 citations

Interfering with Apoptosis: Ca ²⁺ -Binding Protein ALG-2 and Alzheimer's Disease Gene ALG-3

1996 • 481 citations

Molecular structure and functional characterization of a human complement cytolysis inhibitor found in blood and seminal plasma: identity to sulfated glycoprotein 2, a constituent of rat testis fluid.

1989 • 412 citations

Purification and characterization of a cell-aggregating factor (clusterin), the major glycoprotein in ram rete testis fluid.

1983 • 399 citations

Anti‐inflammatory agents as a therapeutic approach to Alzheimer's disease

1992 • 396 citations

Are reactive oxygen species involved in Alzheimer's disease?

1995 • 358 citations

Clusterin: the intriguing guises of a widely expressed glycoprotein

1992 • 353 citations

Identification of a distinct human high‐density lipoprotein subspecies defined by a lipoprotein‐associated protein, K‐45

1993 • 350 citations

Clusterin (apoJ) Alters the Aggregation of Amyloid β-Peptide (Aβ1-42) and Forms Slowly Sedimenting Aβ Complexes That Cause Oxidative Stress

1995 • 343 citations

Dynamics of gene expression for a hippocampal glycoprotein elevated in Alzheimer's disease and in response to experimental lesions in rat

1990 • 334 citations

SP-40,40, a newly identified normal human serum protein found in the SC5b-9 complex of complement and in the immune deposits in glomerulonephritis.

1988 • 311 citations

A 70-kDa apolipoprotein designated ApoJ is a marker for subclasses of human plasma high density lipoproteins.

1990 • 260 citations

Changes in brain gene expression shared by scrapie and Alzheimer disease.

1989 • 253 citations

Early‐onset Alzheimer's disease

1987 • 231 citations

A Sulfated Glycoprotein Synthesized by Sertoli Cells and by Epididymal Cells is a Component of the Sperm Membrane 1

1984 • 226 citations

Distribution of clusterin in Alzheimer brain tissue

1992 • 212 citations

Apolipoprotein J Is Associated with Paraoxonase in Human Plasma

1994 • 186 citations

Apolipoprotein J and Alzheimer's amyloid β solubility

1996 • 182 citations

Clusterin, the human apolipoprotein and complement inhibitor, binds to complement C7, C8 beta, and the b domain of C9.

1993 • 177 citations

Brain Expression of Apolipoproteins E, J, and A‐I in Alzheimer's Disease

1996 • 174 citations

Sulfated glycoprotein 2: new relationships of this multifunctional protein to neurodegeneration

1992 • 171 citations

Human clusterin gene expression is confined to surviving cells during in vitro programmed cell death.

1994 • 170 citations

A comparative study of histological and immunohistochemical methods for neurofibrillary tangles and senile plaques in Alzheimer's disease

1992 • 164 citations

SP-40,40 is a constituent of Alzheimer's amyloid

1992 • 160 citations

Clusterin (SGP‐2): A multifunctional glycoprotein with regional expression in astrocytes and neurons of the adult rat brain

1994 • 149 citations

Purification and characterization of apolipoprotein J.

1990 • 134 citations

Murine clusterin: molecular cloning and mRNA localization of a gene associated with epithelial differentiation processes during embryogenesis

1993 • 127 citations

Purification and Characterization of Brain Clusterin

1994 • 117 citations

SP-40,40 is an inhibitor of C5b-6-initiated haemolysis

1989 • 115 citations

Castration Enhances Expression of Glial Fibrillary Acidic Protein and Sulfated Glycoprotein-2 in the Intact and Lesion-Altered Hippocampus of the Adult Male Rat

1990 • 113 citations

Clusterin (Apo J) Protects Against In Vitro Amyloid‐β(1–40) Neurotoxicity

1996 • 102 citations

Lack of correspondence between mRNA expression for a putative cell death molecule (SGP‐2) and neuronal cell death in the central nervous system

1991 • 99 citations

Selective expression of clusterin (SGP-2) and complement C1qB and C4 during responses to neurotoxinsin vivo andin vitro

1994 • 97 citations

Distinct Patterns of Neuronal Loss and Alzheimerʼs Disease Lesion Distribution in Elderly Individuals Older than 90 Years

1996 • 97 citations

Structural analysis of clusterin and its subunits in ram rete testis fluid

1988 • 84 citations

Alzheimer's Disease and Other Dementing Disorders

1992 • 75 citations

Characterization of the Products of a Gene Expressed During Androgen-Programmed Cell Death and their Potential use as a Marker of Urogenital Injury

1990 • 73 citations

Response of striatal astrocytes to neuronal deafferentation: An immunocytochemical and ultrastructural study

1994 • 68 citations

Diverse Secretory Patterns of Clusterin by Epididymis and Prostate/Seminal Vesicles Undergoing Cell Regression after Orchiectomy*

1990 • 67 citations

SGP-2 expression as a genetic marker of progressive cellular pathology in experimental hydronephrosis

1991 • 67 citations

Altered Gene Expression in Alzheimer's Disease Brain Tissue

1989 • 64 citations

Regulation of Clusterin Secretion and mRNA Expression in Astrocytes by Cytokines

1994 • 59 citations

Oxidative damage in Alzheimer’s disease

2015 • 56 citations

Sulfated glycoprotein-2 (SGP-2) mRNA is expressed in rat striatal astrocytes following ibotenic acid lesions

1991 • 54 citations

Presenilin-1-immunoreactive neurons are preserved in late-onset Alzheimer's disease.

1997 • 53 citations

Relationship between multifunctional protein “clusterin” and Alzheimer disease

1996 • 51 citations

Expression of the complement membrane attack complex and its inhibitors in Pick disease brain

1994 • 46 citations

Elevation of human cerebrospinal fluid clusterin concentration is associated with acute neuropathology

1993 • 40 citations

Sertoli Cells, Proximal Convoluted Tubules in the Kidney, and Neurons in the Brain Contain Cyclic Protein-21

1990 • 35 citations

Differential expression of clusterin in inducible models of apoptosis

1992 • 34 citations

Perforant Path Transection Induces Complement C9 Deposition in Hippocampus

1996 • 33 citations

Dementia in the Oldest-Old:Quantitative Analysis of 12 Cases from a Psychiatric Hospital

1994 • 24 citations

Increases in sulphated glycoprotein-2 mRNA levels in the rat brain after transient forebrain ischemia or partial mesodiencephalic hemitransection

1993 • 24 citations

Neuronal expression of STM2 mRNA in human brain is reduced in Alzheimer's disease.

1996 • 15 citations