Cytosine-cytosine+ base pairing stabilizes DNA quadruplexes and cytosine methylation greatly enhances the effect

CpG-rich islands and the function of DNA methylation

1986 • 3,760 citations

Formation of parallel four-stranded complexes by guanine-rich motifs in DNA and its implications for meiosis

1988 • 1,734 citations

Monovalent cation-induced structure of telomeric DNA: The G-quartet model

1989 • 1,202 citations

Inhibition of telomerase by G-quartet DMA structures

1991 • 1,086 citations

Telomeric DNA dimerizes by formation of guanine tetrads between hairpin loops

1989 • 939 citations

A sodium-potassium switch in the formation of four-stranded G4-DNA

1990 • 789 citations

Telomeric DNA oligonucleotides form novel intramolecular structures containing guanine·guanine base pairs

1987 • 675 citations

In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs

1990 • 632 citations

A Fourier method for the analysis of exponential decay curves

1976 • 590 citations

Quadruplex structure of Oxytricha telomeric DNA oligonucleotides

1992 • 520 citations

Defective acidification of intracellular organelles in cystic fibrosis

1991 • 490 citations

Alternative chromatin structure at CpG islands

1990 • 480 citations

A new empirical method to calculate average molecular polarizabilities

1979 • 423 citations

Four-Stranded Nucleic Acid Structures 25 Years Later: From Guanosine Gels to Telomer DNA

1990 • 404 citations

THE ISOCHORE ORGANIZATION OF THE HUMAN GENOME

1989 • 369 citations

A truncated human chromosome 16 associated with α thalassaemia is stabilized by addition of telomeric repeat (TTAGGG)n

1990 • 288 citations

Cation-dependent transition between the quadruplex and Watson-Crick hairpin forms of d(CGCG3GCG)

1992 • 279 citations

Solution structure of an unusually stable RNA tetraplex containing G- and U-quartet structures

1992 • 261 citations

Monovalent cation induced structural transitions in telomeric DNAs: G-DNA folding intermediates

1991 • 245 citations

Bioenergetics and the problem of tumor growth.

1972 • 240 citations

Spectrophotometric studies on nucleic acid derivatives and related compounds as a function of pH

1952 • 184 citations

Isolation of Sequences that Span the Fragile X and Identification of a Fragile X-Related CpG Island

1991 • 174 citations

Wilms Tumor Locus on 11p13 Defined by Multiple CpG Island-Associated Transcripts

1990 • 143 citations

Influence of pH on the equilibrium association constants for oligodeoxyribonucleotide-directed triple helix formation at single DNA sites

1992 • 142 citations

Stabilities of consecutive A.cntdot.C, C.cntdot.C, G.cntdot.G, U.cntdot.C, and U.cntdot.U mismatches in RNA internal loops: evidence for stable hydrogen-bonded U.cntdot.U and C.cntdot.C+ pairs

1991 • 136 citations

Effect of monovalent cation-induced telomeric DNA structure on the binding of Oxytricha telomeric protein

1990 • 113 citations

Base stacking and molecular polarizability: Effect of a methyl group in the 5-position of pyrimidines

1987 • 112 citations

Retinoblastoma susceptibility genes contain 5' sequences with a high propensity to form guanine-tetrad structures

1992 • 112 citations

Direct observation of a DNA quadruplex by electrospray ionization mass spectrometry

1993 • 107 citations

DNA base modification: Ionized base pairs and mutagenesis

1987 • 105 citations

Tetraplex Formation of a Guanine-Containing Nonameric DNA Fragment

1990 • 105 citations

NMR structural studies of intramolecular (Y+)n.cntdot.(R+)n(Y-)n DNA triplexes in solution: imino and amino proton and nitrogen markers of G.cntdot.AT base triple formation

1991 • 72 citations

An unusual DMA structure detected in a telomeric sequence under superhelical stress and at low pH

1989 • 65 citations

Single-strand DNA triple-helix formation

1990 • 65 citations

Self base pairing in a complementary deoxydinucleoside monophosphate duplex: crystal and molecular structure of deoxycytidylyl-(3'-5')-deoxyguanosine

1983 • 61 citations

Information loss with transform methods in system identification: a new set of transforms with high information content

1980 • 47 citations

A.cntdot.T and C.cntdot.C+ base pairs can form simultaneously in a novel multistranded DNA complex

1990 • 35 citations

Formation of novel hairpin structures by telemeric C-strand oligonucleotides

1992 • 34 citations

Chromatin aggregation changes substantially as pH varies within the physiological range

1989 • 33 citations

A G4-DNA/B-DNA junction at codon 12 of c-Ha-ras is actively and asymmetrically methylated by DNA (cytosine-5)methyltransferase

1989 • 26 citations

Reverse transcriptase, the end of the chromosome, and the end of life

1990 • 23 citations

The nature of drastic differences in the recognition of protonated cytidinium and deoxycytidinium cations by their parent nucleosides within dihydrogenphosphate salts in the light of the computer-simulated crystal structure of dCyd hemiphosphate (dCyd)2H+ H2PO−*4

1990 • 9 citations