Genetic models of schizophrenia and bipolar disorder

Translational Findings on Brain-Derived Neurotrophic Factor and Anxiety: Contributions from Basic Research to Clinical Practice

2013 • 3,921 citations

The BDNF val66met Polymorphism Affects Activity-Dependent Secretion of BDNF and Human Memory and Hippocampal Function

2003 • 3,746 citations

Effect of COMT Val ^108/158 Met genotype on frontal lobe function and risk for schizophrenia

2001 • 2,408 citations

Neuregulin 1 and Susceptibility to Schizophrenia

2002 • 1,654 citations

Genome Scan Meta-Analysis of Schizophrenia and Bipolar Disorder, Part II: Schizophrenia

2003 • 1,160 citations

Oligodendrocyte dysfunction in schizophrenia and bipolar disorder

2003 • 911 citations

Genetic Variation in the 6p22.3 Gene DTNBP1, the Human Ortholog of the Mouse Dysbindin Gene, Is Associated with Schizophrenia

2002 • 842 citations

Genetic and physiological data implicating the new human gene G72 and the gene for <scp>d</scp> -amino acid oxidase in schizophrenia

2002 • 828 citations

Meta-analysis of whole-genome linkage scans of bipolar disorder and schizophrenia

2002 • 824 citations

Schizophrenia and Affective Disorders—Cosegregation with a Translocation at Chromosome 1q42 That Directly Disrupts Brain-Expressed Genes: Clinical and P300 Findings in a Family

2001 • 729 citations

A Highly Significant Association between a COMT Haplotype and Schizophrenia

2002 • 701 citations

The Brain-Derived Neurotrophic Factor Gene Confers Susceptibility to Bipolar Disorder: Evidence from a Family-Based Association Study

2002 • 604 citations

Genome Scan Meta-Analysis of Schizophrenia and Bipolar Disorder, Part III: Bipolar Disorder

2003 • 573 citations

Family-based association study of 76 candidate genes in bipolar disorder: BDNF is a potential risk locus

2002 • 570 citations

Association of Neuregulin 1 with Schizophrenia Confirmed in a Scottish Population

2003 • 557 citations

The 22q11 deletion syndromes

2000 • 492 citations

A Longitudinal Study of Premorbid IQ Score and Risk of Developing Schizophrenia,Bipolar Disorder, Severe Depression, and Other Nonaffective Psychoses

2004 • 462 citations

A Twin Study of Genetic Relationships Between Psychotic Symptoms

2002 • 460 citations

Morbidity Risks of Schizophrenia and Affective Disorders among First Degree Relatives of Patients with Schizophrenia, Mania, Depression and Surgical Conditions

1980 • 432 citations

Density of Glutamic Acid Decarboxylase 67 Messenger RNA–ContainingNeurons That Express the N-Methyl-D-AspartateReceptor Subunit NR2A in the Anterior Cingulate Cortex in Schizophreniaand Bipolar Disorder

2004 • 408 citations

Molecular abnormalities of the hippocampus in severe psychiatric illness: postmortem findings from the Stanley Neuropathology Consortium

2004 • 396 citations

Disrupted-in-Schizophrenia-1 (DISC-1): Mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth

2002 • 387 citations

Continuity and Discontinuity of Affective Disorders and Schizophrenia

1993 • 379 citations

Support for Association of Schizophrenia with Genetic Variation in the 6p22.3 Gene, Dysbindin, in Sib-Pair Families with Linkage and in an Additional Sample of Triad Families

2003 • 368 citations

Association Between a Functional Catechol O-Methyltransferase Gene Polymorphism and Schizophrenia: Meta-Analysis of Case-Control and Family-Based Studies

2003 • 348 citations

A Controlled Family Study of Chronic Psychoses

1988 • 347 citations

Psychiatric genetics: search for phenotypes

1998 • 334 citations

Chromosome 1 loci in Finnish schizophrenia families

2001 • 315 citations

Examination of G72 and D-amino-acid oxidase as genetic risk factors for schizophrenia and bipolar affective disorder

2004 • 313 citations

Individual and Familial Risk Factors for Bipolar Affective Disorders in Denmark

2003 • 304 citations

A Genomewide Screen for Schizophrenia Genes in an Isolated Finnish Subpopulation, Suggesting Multiple Susceptibility Loci

1999 • 286 citations

Serotonin 5-HT1A, 5-HT1B, and 5-HT2A receptor mRNA expression in subjects with major depression, bipolar disorder, and schizophrenia

2004 • 283 citations

Genome scan of European-American schizophrenia pedigrees: Results of the NIMH genetics initiative and millennium consortium

1998 • 278 citations

Polymorphisms at the G72/G30 Gene Locus, on 13q33, Are Associated with Bipolar Disorder in Two Independent Pedigree Series*

2003 • 270 citations

Asymmetrical reductions of hippocampal NMDAR1 glutamate receptor mRNA in the psychoses

2001 • 224 citations

Initial genome scan of the NIMH genetics initiative bipolar pedigrees: Chromosomes 1, 6, 8, 10, and 12

1997 • 218 citations

Genetic variation in the 22q11 locus and susceptibility to schizophrenia

2002 • 199 citations

Evidence for shared susceptibility in bipolar disorder and schizophrenia

2003 • 196 citations

Is the G72/G30 locus associated with schizophrenia? single nucleotide polymorphisms, haplotypes, and gene expression analysis

2004 • 185 citations

Abnormalities of the NMDA Receptor and Associated Intracellular Molecules in the Thalamus in Schizophrenia and Bipolar Disorder

2004 • 173 citations

COMT: A common susceptibility gene in bipolar disorder and schizophrenia

2004 • 165 citations

The New York High-Risk Project

1997 • 160 citations

The Roscommon Family Study

1993 • 150 citations

Polymorphisms in the 13q33.2 gene G72/G30 are associated with childhood-onset schizophrenia and psychosis not otherwise specified

2004 • 145 citations

Association study of the brain-derived neurotrophic factor (BDNF) gene with bipolar disorder

2003 • 142 citations

Molecular analysis of velo-cardio-facial syndrome patients with psychiatric disorders.

1997 • 140 citations

Findings in an independent sample support an association between bipolar affective disorder and the G72/G30 locus on chromosome 13q33

2003 • 131 citations

Genotype-Phenotype Studies in Bipolar Disorder Showing Association Between the DAOA/G30 Locus and Persecutory Delusions: A First Step Toward a Molecular Genetic Classification of Psychiatric Phenotypes

2005 • 131 citations

Event-related Potentials (ERPs) as Indicators of Risk for Schizophrenia

1994 • 113 citations

Further evidence for a susceptibility locus on chromosome 10p14-p11 in 72 families with schizophrenia by nonparametric linkage analysis.

1998 • 112 citations

The C270T polymorphism of the brain-derived neurotrophic factor gene is associated with schizophrenia

2003 • 106 citations

Increased morbid risk for schizophrenia in families of in-patients with bipolar illness

2000 • 106 citations

Association of G72/G30 with schizophrenia in the Chinese population

2004 • 104 citations

The genetics of schizophrenia: glutamate not dopamine?

2003 • 101 citations

Further evidence for a susceptibility locus on chromosome 10p14-p11 in 72 families with schizophrenia by nonparametric linkage analysis

1998 • 98 citations

Suggestive evidence of a locus on chromosome 10p using the NIMH genetics initiative bipolar affective disorder pedigrees

2000 • 80 citations

The dichotomy of schizophrenia and affective disorders in extended pedigrees

2002 • 76 citations

An overview of the genetics of psychotic mood disorders

2003 • 68 citations

Clinical phenotypes associated with DISC1, a candidate gene for schizophrenia

2004 • 67 citations

Information processing deficits in relatives of manic depressive patients

2000 • 63 citations

Multicenter linkage study of schizophrenia loci on chromosome 22q

2004 • 58 citations

Dissecting complex behaviours in the post-genomic era

2004 • 57 citations

Association of tumor necrosis factor alpha gene -G308A polymorphism with schizophrenia

2003 • 54 citations

Polymorphism Screening of PIP5K2A: A Candidate Gene for Chromosome 10p‐Linked Psychiatric Disorders

2003 • 46 citations

Brain-derived neurotrophic factor as a potential risk locus for bipolar disorder: Evidence, limitations, and implications

2003 • 45 citations

Update on chromosomal locations for psychiatric disorders: Report of the interim meeting of chromosome workshop chairpersons from the VIIth World Congress of Psychiatric Genetics, Monterey, California, October 14-18, 1999

2000 • 40 citations

Tumor necrosis factor alpha gene-G308A polymorphism associated with bipolar I disorder in the Korean population

2003 • 39 citations

Genetic Insights into Schizophrenia

2001 • 26 citations

Can long-range microsatellite data be used to predict short-range linkage disequilibrium?

2002 • 22 citations