Role of direct interaction in BRCA1 inhibition of estrogen receptor activity

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

A Strong Candidate for the Breast and Ovarian Cancer Susceptibility Gene BRCA1

1994 • 5,994 citations

The Risk of Cancer Associated with Specific Mutations ofBRCA1andBRCA2among Ashkenazi Jews

1997 • 2,255 citations

Risks of cancer in BRCA1-mutation carriers

1994 • 1,865 citations

Confirmation of BRCA1 by analysis of germline mutations linked to breast and ovarian cancer in ten families

1994 • 626 citations

BRCA1 Inhibition of Estrogen Receptor Signaling in Transfected Cells

1999 • 494 citations

Evidence for a transcriptional activation function of BRCA1 C-terminal region

1996 • 443 citations

The C-terminal (BRCT) Domains of BRCA1 Interact in Vivo with CtIP, a Protein Implicated in the CtBP Pathway of Transcriptional Repression

1998 • 383 citations

Estrogen Receptor Activation Function 1 Works by Binding p160 Coactivator Proteins

1998 • 366 citations

BRCA1 interacts with components of the histone deacetylase complex

1999 • 330 citations

Cloning and sequence analysis of cDNA for human cathepsin D.

1985 • 318 citations

Regulation of the Ets-Related Transcription Factor Elf-1 by Binding to the Retinoblastoma Protein

1993 • 220 citations

AF-2 Activity and Recruitment of Steroid Receptor Coactivator 1 to the Estrogen Receptor Depend on a Lysine Residue Conserved in Nuclear Receptors

1997 • 214 citations

Immortalized and tumorigenic adult human prostatic epithelial cell lines: Characteristics and applications part 2. Tumorigenic cell lines

1997 • 208 citations

Steroid receptors in hereditary breast carcinomas associated with BRCA1 or BRCA2 mutations or unknown susceptibility genes

1998 • 185 citations

Structure of the human oestrogen-responsive gene pS2

1987 • 113 citations

BRCA1 as a potential human prostate tumor suppressor: modulation of proliferation, damage responses and expression of cell regulatory proteins

1998 • 100 citations

Emerging roles of BRCA1 in transcriptional regulation and DNA repair

1999 • 77 citations

Reducing the Risk of Breast Cancer

2000 • 67 citations