Relationships between lower plasma L-tryptophan levels and immune-inflammatory variables in depression

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Fundamental Immunology

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Relationships between interleukin-6 activity, acute phase proteins, and function of the hypothalamic-pituitary-adrenal axis in severe depression

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NEUTRAL AMINO ACIDS IN THE BRAIN: CHANGES IN RESPONSE TO FOOD INGESTION

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THE EFFECTS OF PRECURSOR LOADING IN THE CEREBRAL METABOLISM OF 5‐HYDROXYINDOLES

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New chromogenic substrates for X-prolyl dipeptidyl-aminopeptidase

1976 • 316 citations

Nutritional Aspects of Leukocytic Cytokines

1988 • 303 citations

Evidence for a systemic immune activation during depression: results of leukocyte enumeration by flow cytometry in conjunction with monoclonal antibody staining

1992 • 269 citations

Cachectin/TNF or IL-1 alpha induces cachexia with redistribution of body proteins

1989 • 261 citations

Depression‐related disturbances in mitogen‐induced lymphocyte responses and interleukin‐1β and soluble interleukin‐2 receptor production

1991 • 259 citations

Interleukin 1 receptor blockade attenuates the host inflammatory response.

1990 • 216 citations

Decreased serum tryptophan in patients with HIV-1 infection correlates with increased serum neopterin and with neurologic/psychiatric symptoms.

1990 • 203 citations

Interferon-lnduced Indoleamine 2,3-Dioxygenase Activity in Human Mononuclear Phagocytes

1989 • 187 citations

Progress in Tryptophan and Serotonin Research

1984 • 184 citations

Leukocytosis, monocytosis and neutrophilia: Hallmarks of severe depression

1992 • 172 citations

Correlation between brain tryptophan and plasma neutral amino acid levels following food consumption in rats

1973 • 170 citations

TOTAL AND FREE TRYPTOPHAN CONCENTRATION IN THE PLASMA OF DEPRESSIVE PATIENTS

1973 • 163 citations

Stress‐and Endotoxin‐Induced Increases in Brain Tryptophan and Serotonin Metabolism Depend on Sympathetic Nervous System Activity

1991 • 157 citations

Decreased plasma tryptophan levels in major depression

1989 • 154 citations

Higher α1-antitrypsin, haptoglobin, ceruloplasmin and lower retinol binding protein plasma levels during depression: Further evidence for the existence of an inflammatory response during that illness

1992 • 145 citations

Virus infection as a stressor: Influenza virus elevates plasma concentrations of corticosterone, and brain concentrations of MHPG and tryptophan

1989 • 141 citations

Increased endogenous interferon-gamma and neopterin correlate with increased degradation of tryptophan in human immunodeficiency virus type 1 infection

1991 • 139 citations

Interleukin 1, tumour necrosis factor‐alpha (cachectin) and the pathogenesis of cancer cachexia

1987 • 129 citations

Current Concepts of Protein Turnover and Amino Acid Transport in Liver and Skeletal Muscle During Sepsis

1988 • 124 citations

Disturbances in acute phase plasma proteins during melancholia: Additional evidence for the presence of an inflammatory process during that illness

1992 • 124 citations

Plasma Tryptophan and Five Other Amino Acids in Depressed and Normal Subjects

1981 • 119 citations

Branched chain amino acid administration and metabolism during starvation, injury, and infection.

1979 • 118 citations

Biological and clinical effects of intravenous tumor necrosis factor-alpha administered three times weekly.

1991 • 112 citations

The functions and regulation of tryptophan pyrrolase

1977 • 112 citations

Antiphospholipid, antinuclear, epstein-barr and cytomegalovirus antibodies, and soluble interleukin-2 receptors in depressive patients

1991 • 108 citations

Modulation of Quinolinic and Kynurenic Acid Content in the Rat Brain: Effects of Endotoxins and Nicotinylalanine

1991 • 103 citations

Interleukin-6: historical background, genetics and biological significance

1990 • 98 citations

The actions of interferon and antiinflammatory agents on induction of indoleamine 2,3-dioxygenase in human peripheral blood monocytes

1987 • 97 citations

New Results in Depression Research

1986 • 91 citations

Altered tryptophan and neopterin metabolism in cancer patients treated with recombinant interleukin 2.

1989 • 82 citations

Increased biogenic amine release in mouse hypothalamus following immunological challenge: antagonism by indomethacin

1990 • 77 citations

Psychomotor retardation, anorexia, weight loss, sleep disturbances, and loss of energy: Psychopathological correlates of hyperhaptoglobinemia during major depression

1993 • 72 citations

Anthropometric and biochemical assessment of the nutritional state in depression: evidence for lower visceral protein plasma levels in depression

1991 • 69 citations

Suppressant effects of dexamethasone on the availability of plasma L‐tryptophan and tyrosine in healthy controls and in depressed patients

1990 • 67 citations

Decreased serum dipeptidyl peptidase IV activity in major depression

1991 • 65 citations

A Biochemical and Neuroendocrine Study of the Serotonergic System in Depression

1986 • 62 citations

Amino Acid Availability and Brain Function in Health and Disease

1988 • 60 citations

A significantly increased number and percentage of B cells in depressed subjects: results of flow cytometric measurements

1992 • 59 citations

Prediction of subtype and severity of depression by means of dexamethasone suppression test, l-tryptophan: Competing amino acid ratio and MHPG flow

1987 • 58 citations

Relationship between the dexamethasone suppression test and the l-tryptophan/competing amino acids ratio in depression

1987 • 50 citations

Disturbances in dexamethasone suppression test and lower availability of Ł-tryptophan and tyrosine in early puerperium and in women under contraceptive therapy

1992 • 46 citations

Plasma tryptophan and tyrosine ratios to competing amino acids in relation to antidepressant response to citalopram and maprotiline

1986 • 42 citations

RAPID EFFECTS OF ENVIRONMENTAL DISTURBANCE ON RAT PLASMA UNESTERIFIED FATTY ACID AND TRYPTOPHAN CONCENTRATIONS AND THEIR PREVENTION BY ANTILIPOLYTIC DRUGS

1975 • 41 citations

Clinical subtypes of unipolar depression: Part III. Quantitative differences in various biological markers between the cluster-analytically generated nonvital and vital depression classes

1990 • 40 citations

The Common Pathophysiology of Monoaminergic Psychoses: a New Hypothesis

1975 • 37 citations

Effects of dexamethasone on the availability of l-tryptophan and on the insulin and FFA concentrations in unipolar depressed patients

1990 • 37 citations

Free and total plasma tryptophan in endogenous depression

1979 • 32 citations

The effects of glucocorticoids on the availability of L-tryptophan and tyrosine in the plasma of depressed patients

1990 • 29 citations

Depressive disorders and immunity

1990 • 28 citations

The clinical significance of disordered renal excretion of xanthurenic acid in depressive patients

1981 • 24 citations

Effects of a suppression test dose of dexamethasone on tryptophan metabolism and disposition in the rat

1989 • 22 citations

The relationships between the availability ofL-tryptophan to the brain, the spontaneous HPA-axis activity, and the HPA-axis responses to dexamethasone in depressed patients

1991 • 21 citations

Blood-Brain Movements of Tryptophan and Tyrosine in Manic-Depressive Illness and Schizophrenia

1979 • 21 citations

Effects of Adrenaline Injection on Human Plasma Tryptophan and Non-Esterified Fatty Acids

1977 • 20 citations

The decreased availability of L-tryptophan in depressed females: Clinical and biological correlates

1990 • 19 citations

The renal excretion of xanthurenic acid following <scp>L</scp>‐tryptophan loading in depressed patients

1987 • 16 citations

Enhancement of Indoleamine 2,3-Dioxygenase Activity in Cancer Patients Receiving Interferon-β_Ser

1989 • 15 citations

[Inflammatory syndrome and changes in plasma proteins].

1986 • 14 citations

Study of disturbed tryptophan metabolism in depressive illness.

1979 • 11 citations

Bioavailability of Amino Acids and Amino Acid Precursors for Neurotransmitter Action: The Role of Hormones

1988 • 11 citations

PLASMA TRYPTOPHAN, AGE AND DEPRESSION

1985 • 7 citations

[Erythrocyte membrane transport of L-tyrosine and L-tryptophan in 66 patients with depressive syndromes. Preliminary results].

1986 • 2 citations