A novel mutation in the TPO gene in goitrous hypothyroid patients with iodide organification defect

Human thyroid peroxidase: complete cDNA and protein sequence, chromosome mapping, and identification of two alternately spliced mRNAs.

1987 • 286 citations

Identification of a mutation in the coding sequence of the human thyroid peroxidase gene causing congenital goiter.

1992 • 193 citations

Molecular cloning of the human eosinophil peroxidase. Evidence for the existence of a peroxidase multigene family.

1989 • 190 citations

Characterization of cDNA clones for human myeloperoxidase: Predicted amino acid sequence and evidence for multiple mRNA species

1987 • 169 citations

Structure of the human thyroid peroxidase gene: comparison and relationship to the human myeloperoxidase gene

1989 • 151 citations

Molecular cloning and characterization of cDNA for human myeloperoxidase.

1987 • 142 citations

Chromosomal gene structure of human myeloperoxidase and regulation of its expression by granulocyte colony-stimulating factor.

1987 • 113 citations

Identification of five novel inactivating mutations in the human thyroid peroxidase gene by denaturing gradient gel electrophoresis

1995 • 109 citations

Molecular cloning and characterization of a chromosomal gene for human eosinophil peroxidase

1989 • 106 citations

Molecular Analysis of Mutated Thyroid Peroxidase Detected in Patients with Total Iodide Organification Defects¹

1997 • 90 citations

Molecular Cloning of cDNAs Encoding Bovine and Human Lactoperoxidase

1990 • 80 citations

Mutation Detection by PCR, GC-Clamps, and Denaturing Gradient Gel Electrophoresis

1989 • 69 citations

cDNA cloning of human myeloperoxidase: decrease in myeloperoxidase mRNA upon induction of HL-60 cells.

1987 • 69 citations

Molecular Analysis of Mutated Thyroid Peroxidase Detected in Patients with Total Iodide Organification Defects

1997 • 67 citations

A 20-basepair duplication in the human thyroid peroxidase gene results in a total iodide organification defect and congenital hypothyroidism.

1994 • 64 citations

Molecular cloning of the structural gene for porcine thyroid peroxidase.

1987 • 62 citations

Peroxydase particulaire thyroïdienne

1972 • 58 citations

Congenital hypothyroidism caused by a premature termination signal in exon 10 of the human thyroid peroxidase gene.

1996 • 50 citations

Generation of a Biologically Active, Secreted Form of Human Thyroid Peroxidase by Site-Directed Mutagenesis

1990 • 41 citations

Prediction of domain organisation and secondary structure of thyroid peroxidase, a human autoantigen involved in destructive thyroiditis

1990 • 39 citations

Genetic Linkage Studies of Thyroid Peroxidase (TPO) Gene in Families with TPO Deficiency*

1991 • 36 citations

Regional localization of the gene for thyroid peroxidase to human chromosome 2pter→p12

1988 • 34 citations

A 20-basepair duplication in the human thyroid peroxidase gene results in a total iodide organification defect and congenital hypothyroidism

1994 • 33 citations

Congenital hypothyroidism caused by a premature termination signal in exon 10 of the human thyroid peroxidase gene

1996 • 31 citations

Complete nucleotide sequence of the cDNA for thyroid peroxidase in FRTL5 rat thyroid cells

1989 • 31 citations

Investigation of the ZFY gene in XX true hermaphroditism and Swyer syndrome

1990 • 26 citations

Nucleotide sequence of the cDNA encoding mouse thyroid peroxidase

1993 • 26 citations

Thyroid Iodine Organification Defects: A Case With Lack of Thyroglobulin Iodination and a Case Without Any Peroxidase Activity

1976 • 25 citations

Clinical, pathological, and molecular studies of two families with lodide organification defect

1997 • 4 citations