Mapping the Protein Universe

Dictionary of protein secondary structure: Pattern recognition of hydrogen‐bonded and geometrical features

1983 • 14,802 citations

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

The protein data bank: A computer-based archival file for macromolecular structures

1977 • 8,627 citations

SCOP: A structural classification of proteins database for the investigation of sequences and structures

1995 • 6,372 citations

Protein Structure Comparison by Alignment of Distance Matrices

1993 • 3,989 citations

The Anatomy and Taxonomy of Protein Structure

1981 • 3,376 citations

The structure of proteins: Two hydrogen-bonded helical configurations of the polypeptide chain

1951 • 2,750 citations

Database of homology‐derived protein structures and the structural meaning of sequence alignment

1991 • 1,641 citations

The New Genomics: Global Views of Biology

1996 • 1,174 citations

Crystal Structure of the Cytochrome bc ₁ Complex from Bovine Heart Mitochondria

1997 • 934 citations

Correspondence Analysis: A Neglected Multivariate Method

1974 • 836 citations

Nucleation, Rapid Folding, and Globular Intrachain Regions in Proteins

1973 • 826 citations

The 2.2 Å crystal structure of transducin-α complexed with GTPγS

1993 • 788 citations

Configurations of Polypeptide Chains With Favored Orientations Around Single Bonds

1951 • 778 citations

Protein structure alignment

1989 • 683 citations

Multiple protein sequence alignment from tertiary structure comparison: Assignment of global and residue confidence levels

1992 • 655 citations

PRINCIPLES THAT DETERMINE THE STRUCTURE OF PROTEINS

1984 • 645 citations

Definition of general topological equivalence in protein structures

1990 • 506 citations

Crystal Structure of Rat DNA Polymerase β: Evidence for a Common Polymerase Mechanism

1994 • 464 citations

Codon frequencies in 119 individual genes confirm corsistent choices of degenerate bases according to genome type

1980 • 370 citations

The crystal structure of a two zinc-finger peptide reveals an extension to the rules for zinc-finger/DNA recognition

1993 • 347 citations

The FSSP database of structurally aligned protein fold families.

1994 • 323 citations

The protein threading problem with sequence amino acid interaction preferences is NP-complete

1994 • 280 citations

Identification of Tertiary Structure Resemblance in Proteins Using a Maximal Common Subgraph Isomorphism Algorithm

1993 • 278 citations

Parser for protein folding units

1994 • 229 citations

Detection of common three‐dimensional substructures in proteins

1991 • 197 citations

Structural similarity of DNA-binding domains of bacteriophage repressors and the globin core

1993 • 194 citations

2.3 Å crystal structure of the catalytic domain of DNA polymerase β

1994 • 168 citations

Global Optimum Protein Threading with Gapped Alignment and Empirical Pair Score Functions

1996 • 157 citations

Fast structure alignment for protein databank searching

1992 • 140 citations

A search for the most stable folds of protein chains

1991 • 135 citations

General architecture of the α-helical globule

1988 • 134 citations

Are protein folds atypical?

1998 • 127 citations

Classification of protein folds

1994 • 113 citations

A structural census of the current population of protein sequences

1997 • 106 citations

Polyadenylic acid in the cytoplasm of rat liver

1966 • 91 citations

Common spatial arrangements of backbone fragments in homologous and non-homologous proteins

1992 • 89 citations

An Efficient Automated Computer Vision Based Technique for Detection of Three Dimensional Structural Motifs in Proteins

1992 • 86 citations

[5] Conformation of β hairpins in protein structures: Classification and diversity in homologous structures

1991 • 83 citations

Proceedings Of The Third International Conference On Intelligent Systems For Molecular Biology

1995 • 75 citations

High-resolution solution structure of the double Cys2His2 zinc finger from the human enhancer binding protein MBP-1

1992 • 63 citations

Evolutionary link between glycogen phosphorylase and a DNA modifying enzyme.

1995 • 63 citations

The crystal structure of human CskSH3: structural diversity near the RT‐Src and n‐Src loop

1994 • 62 citations

Structural superposition of proteins with unknown alignment and detection of topological similarity using a six‐dimensional search algorithm

1995 • 60 citations

Structure of monoclinic papain at 1.60 Å resolution

1992 • 59 citations

Protein Architecture: A Practical Approach

1991 • 59 citations

Structural Similarity between Two-layer α/β and β-Proteins

1995 • 49 citations

Molecular structure matching by simulated annealing. III. The incorporation of null correspondences into the matching problem

1991 • 48 citations

Bioinformatics and the discovery of gene function

1996 • 48 citations

PDBBrowse — a graphics interface to the Brookhaven Protein Data Bank

1995 • 37 citations

Protein Architecture: A Practical Approach

1992 • 35 citations

The ‘cerebellum’ and the control of eye movements in cephalopods

1976 • 34 citations

How Many Protein Folding Motifs are There?

1995 • 30 citations

Crystal structure of muconolactone isomerase at 3.3 Å resolution

1989 • 26 citations

Protein A from Staphylococcus aureus conversion of complement factor C3 by aggregates between IgG and protein A

1971 • 14 citations

Three-dimensional pattern matching in protein structure analysis

1995 • 13 citations

The Fermentation of Urine and the Germ Theory

1876 • 4 citations

Earth Pressure Cell

1964 • 2 citations