The Cystic Fibrosis Transmembrane Conductance Regulator Activates Aquaporin 3 in Airway Epithelial Cells

CFTR as a cAMP-Dependent Regulator of Sodium Channels

1995 • 1,074 citations

CFTR expression and chloride secretion in polarized immortal human bronchial epithelial cells.

1994 • 922 citations

Submucosal glands are the predominant site of CFTR expression in the human bronchus

1992 • 644 citations

Molecular cloning and expression of a member of the aquaporin family with permeability to glycerol and urea in addition to water expressed at the basolateral membrane of kidney collecting duct cells.

1994 • 575 citations

Phosphorylation-regulated CI− channel in CHO cells stably expressing the cystic fibrosis gene

1991 • 564 citations

Pathophysiology of the Aquaporin Water Channels

1996 • 492 citations

The Cystic Fibrosis Transmembrane Conductance Regulator

1993 • 438 citations

Aquaporins in complex tissues. II. Subcellular distribution in respiratory and glandular tissues of rat

1997 • 409 citations

Evidence for reduced Cl‐ and increased Na+ permeability in cystic fibrosis human primary cell cultures.

1988 • 265 citations

Cloning and expression of AQP3, a water channel from the medullary collecting duct of rat kidney.

1994 • 264 citations

Expression of the cystic fibrosis gene in adult human lung.

1994 • 248 citations

Heteromultimeric CLC chloride channels with novel properties

1996 • 246 citations

Sensitivity of a renal K+ channel (ROMK2) to the inhibitory sulfonylurea compound glibenclamide is enhanced by coexpression with the ATP-binding cassette transporter cystic fibrosis transmembrane regulator.

1996 • 207 citations

The amiloride-inhibitable Na+ conductance is reduced by the cystic fibrosis transmembrane conductance regulator in normal but not in cystic fibrosis airways.

1998 • 201 citations

Cystic Fibrosis Transmembrane Conductance Regulator Inverts Protein Kinase A-mediated Regulation of Epithelial Sodium Channel Single Channel Kinetics

1997 • 200 citations

Aquaporins in complex tissues. I. Developmental patterns in respiratory and glandular tissues of rat

1997 • 171 citations

Regulation of Epithelial Sodium Channels by the Cystic Fibrosis Transmembrane Conductance Regulator

1996 • 165 citations

Wild type but not ΔF508 CFTR inhibits Na⁺ conductance when coexpressed in Xenopus oocytes

1996 • 160 citations

A Multifunctional Aqueous Channel Formed by CFTR

1992 • 152 citations

Regulation of human airway surface liquid

1995 • 142 citations

Inhibition of epithelial Na⁺currents by intracellular domains of the cystic fibrosis transmembrane conductance regulator

1997 • 142 citations

Fluid transport across cultures of human tracheal glands is altered in cystic fibrosis

1997 • 124 citations

Cl⁻ transport by cystic fibrosis transmembrane conductance regulator (CFTR) contributes to the inhibition of epithelial Na⁺ channels (ENaCs) in Xenopus oocytes co‐expressing CFTR and ENaC

1998 • 119 citations

Chloride channel and chloride conductance regulator domains of CFTR, the cystic fibrosis transmembrane conductance regulator

1998 • 87 citations

Na+ and Cl? conductances in airway epithelial cells: increased Na+ conductance in cystic fibrosis

1995 • 85 citations

In vivo analysis of fluid transport in cystic fibrosis airway epithelia of bronchial xenografts

1996 • 76 citations

Structure and Chromosomal Localization of a Human Water Channel (AQP3) Gene

1995 • 70 citations

Gastrointestinal complications

1992 • 57 citations

Episomal expression of wild-type CFTR corrects cAMP-dependent chloride transport in respiratory epithelial cells.

1996 • 55 citations

Culture-dependent expression of Na+ conductances in airway epithelial cells

1996 • 54 citations

Cystic fibrosis transmembrane conductance regulator activates water conductance in Xenopus oocytes

1997 • 53 citations

Expression of multiple water channel activities in Xenopus oocytes injected with mRNA from rat kidney.

1993 • 53 citations

Epithelial dysfunction in cystic fibrosis lung disease

1983 • 49 citations

Regulation of epithelial ion channels by the cystic fibrosis transmembrane conductance regulator

1996 • 48 citations

Mutations in the putative pore-forming domain of CFTR do not change anion selectivity of the cAMP activated Cl−conductance

1995 • 46 citations

Effect of intracellular pH on agonist-induced [Ca 2+ ] i transients in HT 29 cells

1997 • 18 citations